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Type 2 diabetes and β-cell function

Research group Our main research focus is to unravel molecular mechanisms ensuring β-cell function. Our research efforts involves analyses of the molecular mechanisms by which hyperglycemia negatively affects β-cell function and provokes impaired insulin secretion and amyloid formation. We are also analyzing the mechanisms by which the compound O304/ATX-304, an activator of AMPK and a mitochondrial uncoupler, negates the negative impacts of hyperglycemia on β-cell function and thus restores β-cell function.

Our research

More on grp Helena Edlunds research

Publications

Selected publications from grp Helena Edlund

Our research group

Pictures of Helena Edlunds research group

Head of research

Overview

Participating departments and units at Umeå University

Department of Medical and Translational Biology, Umeå Centre for Molecular Medicine (UCMM)

Research area

Molecular medicine

External funding

Knut and Alice Wallenberg Foundation, Swedish Research Council

External funding

Latest update: 2024-03-07