Christian Hedberg

Contact

christian.hedberg@umu.se

+46 90 786 56 84

Works at

Professor at Department of Chemistry

KB.C4, Linnaeus väg 10, (rum: B4.01.07) Umeå universitet, 901 87 Umeå

Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1

Nature Communications, Nature Research 2021, Vol. 12, (1)

Du, Jiqing; Wrisberg, Marie-Kristin von; Gulen, Burak; et al.

Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD

Nature Communications, Springer Nature 2021, Vol. 12, (1)

Fauser, Joel; Gulen, Burak; Pogenberg, Vivian; et al.

In Vivo Imaging of the Macrophage Migration Inhibitory Factor in Liver Cancer with an Activity-Based Probe

Analytical Chemistry, American Chemical Society (ACS) 2021, Vol. 93, (4) : 2152-2159

Shao, Chenwen; Hedberg, Christian; Qian, Yong

Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion-Dominated Canalicular and Flow-Augmented Ductular Bile Flux

Hepatology, John Wiley & Sons 2021, Vol. 73, (4) : 1531-1550

Vartak, Nachiket; Guenther, Georgia; Joly, Florian; et al.

Legionella effector AnkX displaces the switch II region for Rab1b phosphocholination

Science Advances, American Association for the Advancement of Science 2020, Vol. 6, (20)

Ernst, Stefan; Ecker, Felix; Kaspers, Marietta S.; et al.

Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture

Nature Chemistry, Nature Publishing Group 2020, Vol. 12, (8) : 732-739

Gulen, Burak; Rosselin, Marie; Fauser, Joel; et al.

Monoclonal Anti-AMP Antibodies Are Sensitive and Valuable Tools for Detecting Patterns of AMPylation

iScience, Cambridge: Cell Press 2020, Vol. 23, (12)

Hoepfner, Dorothea; Fauser, Joel; Kaspers, Marietta S.; et al.

Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3

Biochemistry, American Chemical Society (ACS) 2020, Vol. 59, (38) : 3570-3581

Rogne, Per; Dulko-Smith, Beata; Goodman, Jack; et al.

Principles of ATP and GTP Selectivity in NMP Kinases

Biophysical Journal, Cell Press 2020, Vol. 118, (3) : 193A-193A

Rogne, Per; Sauer-Eriksson, Elisabeth; Sauer, Uwe H.; et al.

Photoactivated Colibactin Probes Induce Cellular DNA Damage

Angewandte Chemie International Edition, Vol. 58, (5) : 1417-1421

Moodie, Lindon W. K.; Hubert, Madlen; Zhou, Xin; et al.

Exploring the Substrate Scope of the Bacterial Phosphocholine Transferase AnkX for Versatile Protein Functionalization

ChemBioChem (Print), Wiley-VCH Verlagsgesellschaft 2019, Vol. 20, (18) : 2336-2340

Ochtrop, Philipp; Ernst, Stefan; Itzen, Aymelt; et al.

Positive and Negative Substrate Interference Supported by Coinciding Enzyme Residues

Biophysical Journal, CELL PRESS 2019, Vol. 116, (3) : 485A-485A

Wolf-Watz, Magnus; Rogne, Per; Sauer-Eriksson, A. Elisabeth; et al.

An amphipathic cyclic tetrapeptide scaffold containing halogenated β^2,2-amino acids with activity against multiresistant bacteria

Journal of Peptide Science, John Wiley & Sons 2018, Vol. 24, (10)

Paulsen, Marianne H.; Karlsen, Eskil Andre; Ausbacher, Dominik; et al.

Molecular mechanism of ATP versus GTP selectivity of adenylate kinase

Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, (12) : 3012-3017

Rogne, Per; Rosselin, Marie; Grundström, Christin; et al.

Synthesis and Spectroscopic Properties of Fluorinated Coumarin Lysine Derivatives

Journal of Organic Chemistry, American Chemical Society (ACS) 2018, Vol. 83, (8) : 4792-4799

Shukla, Lakshmi; Moodie, Lindon W. K.; Kindahl, Tomas; et al.

Tetrahydroisoquinolines: New Inhibitors of Neutrophil Extracellular Trap (NET) Formation

ChemBioChem (Print), Wiley-VCH Verlagsgesellschaft 2017, Vol. 18, (10) : 888-893

Martinez, Nancy E.; Zimmermann, Tobias J.; Goosmann, Christian; et al.

Palladium-Mediated Approach to Coumarin-Functionalized Amino Acids

Organic Letters, American Chemical Society (ACS) 2017, Vol. 19, (11) : 2797-2800

Moodie, Lindon W. K.; Chammaa, Samy; Kindahl, Tomas; et al.

Unraveling the Phosphocholination Mechanism of the Legionella pneumophila Enzyme AnkX

Biochemistry, American Chemical Society (ACS) 2016, Vol. 55, (31) : 4375-4385

Gavriljuk, Konstantin; Schartner, Jonas; Seidel, Hans; et al.

Activity-Based Proteome Profiling Probes Based on Woodward's Reagent K with Distinct Target Selectivity

Angewandte Chemie International Edition, Vol. 55, (27) : 7766-7771

Qian, Yong; Schuermann, Marc; Janning, Petra; et al.

The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signaling and gene expression of Legionella pneumophila

Molecular Microbiology, Wiley-Blackwell 2016, Vol. 99, (4) : 778-793

Schell, Ursula; Simon, Sylvia; Sahr, Tobias; et al.

Molecular perspectives on protein adenylylation

ACS Chemical Biology, American Chemical Society (ACS) 2015, Vol. 10, (1) : 12-21

Hedberg, Christian; Itzen, Aymelt

Enzymatic phosphocholination as a tool for protein labeling

The FEBS Journal, Vol. 282 : 12-12

Heller, K; Ochtrop, Philipp; Albers, Michael; et al.

Covalent Protein Labeling by Enzymatic Phosphocholination

Angewandte Chemie International Edition, Vol. 54, (35) : 10327-10330

Heller, Katharina; Ochtrop, Philipp; Albers, Michael F.; et al.

A Concise Total Synthesis of Breitfussin A and B

Organic Letters, Vol. 17, (1) : 122-125

Pandey, Sunil Kumar; Guttormsen, Yngve; Haug, Bengt Erik; et al.

Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway

PLoS Pathogens, Vol. 11, (12)

Simon, Sylvia; Schell, Ursula; Heuer, Natalie; et al.

Exploring the substrate scope of the phosphocholine transferase AnkX for versatile protein functionalisation

Ochtrop, Philipp; Ernst, Stefan; Itzen, Aymelt; et al.

Identification of cellular protein targets for the Legionella pneumophila phosphocholinating effector AnkX

Ochtrop, Philipp; Swart, Leonie; Simon, Sylvia; et al.

View publications in DiVA

Research groups

Head of research

Christian Hedberg Lab

Published: 10 Sep, 2020

A step towards better understanding of bacterial diseases