Hoppa direkt till innehållet
umu.se
För studenter
Bibliotek
För medarbetare
Logga in
Student
Se ditt schema och dina kurser
Redigera
Redigera innehåll på umu.se
English site
Sök
Meny
X stäng menyn
Meny
Sök
Sök inom:
Sök inom:
Allt
Utbildning
Forskning
Personal
Studentwebb
Nyheter
Medarbetarwebb
Andra söktjänster
Hitta kurser och program
Sök kursplan
Sök välkomstbrev
Bibliotekets söktjänst
Huvudmenyn dold.
Logga in
Student
Se ditt schema och dina kurser
Redigera
Redigera innehåll på umu.se
English
Christian Hedberg
Kontakt
E-post
christian.hedberg@umu.se
Telefon
090-786 56 84
Verksam vid
Anknytning
Professor vid
Kemiska institutionen
Plats
KB.C4, Linnaeus väg 10, (rum: B4.01.07)
Umeå universitet, 901 87 Umeå
Publikationer
Publikationer
Forskning
Forskning
Omnämnanden
Omnämnanden
2021
Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1
Nature Communications
, Nature Research 2021, Vol. 12, (1)
Du, Jiqing; Wrisberg, Marie-Kristin von; Gulen, Burak; et al.
2021
Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD
Nature Communications
, Springer Nature 2021, Vol. 12, (1)
Fauser, Joel; Gulen, Burak; Pogenberg, Vivian; et al.
2021
In Vivo Imaging of the Macrophage Migration Inhibitory Factor in Liver Cancer with an Activity-Based Probe
Analytical Chemistry
, American Chemical Society (ACS) 2021, Vol. 93, (4) : 2152-2159
Shao, Chenwen; Hedberg, Christian; Qian, Yong
2021
Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion-Dominated Canalicular and Flow-Augmented Ductular Bile Flux
Hepatology
, John Wiley & Sons 2021, Vol. 73, (4) : 1531-1550
Vartak, Nachiket; Guenther, Georgia; Joly, Florian; et al.
2020
Legionella
effector AnkX displaces the switch II region for Rab1b phosphocholination
Science Advances
, American Association for the Advancement of Science 2020, Vol. 6, (20)
Ernst, Stefan; Ecker, Felix; Kaspers, Marietta S.; et al.
2020
Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture
Nature Chemistry
, Nature Publishing Group 2020, Vol. 12, (8) : 732-739
Gulen, Burak; Rosselin, Marie; Fauser, Joel; et al.
2020
Monoclonal Anti-AMP Antibodies Are Sensitive and Valuable Tools for Detecting Patterns of AMPylation
iScience
, Cambridge: Cell Press 2020, Vol. 23, (12)
Hoepfner, Dorothea; Fauser, Joel; Kaspers, Marietta S.; et al.
2020
Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3
Biochemistry
, American Chemical Society (ACS) 2020, Vol. 59, (38) : 3570-3581
Rogne, Per; Dulko-Smith, Beata; Goodman, Jack; et al.
2020
Principles of ATP and GTP Selectivity in NMP Kinases
Biophysical Journal
, Cell Press 2020, Vol. 118, (3) : 193A-193A
Rogne, Per; Sauer-Eriksson, Elisabeth; Sauer, Uwe H.; et al.
2019
Photoactivated Colibactin Probes Induce Cellular DNA Damage
Angewandte Chemie International Edition
, Vol. 58, (5) : 1417-1421
Moodie, Lindon W. K.; Hubert, Madlen; Zhou, Xin; et al.
2019
Exploring the Substrate Scope of the Bacterial Phosphocholine Transferase AnkX for Versatile Protein Functionalization
ChemBioChem (Print)
, Wiley-VCH Verlagsgesellschaft 2019, Vol. 20, (18) : 2336-2340
Ochtrop, Philipp; Ernst, Stefan; Itzen, Aymelt; et al.
2019
Positive and Negative Substrate Interference Supported by Coinciding Enzyme Residues
Biophysical Journal
, CELL PRESS 2019, Vol. 116, (3) : 485A-485A
Wolf-Watz, Magnus; Rogne, Per; Sauer-Eriksson, A. Elisabeth; et al.
2018
An amphipathic cyclic tetrapeptide scaffold containing halogenated β
2,2
-amino acids with activity against multiresistant bacteria
Journal of Peptide Science
, John Wiley & Sons 2018, Vol. 24, (10)
Paulsen, Marianne H.; Karlsen, Eskil Andre; Ausbacher, Dominik; et al.
2018
Molecular mechanism of ATP versus GTP selectivity of adenylate kinase
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 115, (12) : 3012-3017
Rogne, Per; Rosselin, Marie; Grundström, Christin; et al.
2018
Synthesis and Spectroscopic Properties of Fluorinated Coumarin Lysine Derivatives
Journal of Organic Chemistry
, American Chemical Society (ACS) 2018, Vol. 83, (8) : 4792-4799
Shukla, Lakshmi; Moodie, Lindon W. K.; Kindahl, Tomas; et al.
2017
Tetrahydroisoquinolines: New Inhibitors of Neutrophil Extracellular Trap (NET) Formation
ChemBioChem (Print)
, Wiley-VCH Verlagsgesellschaft 2017, Vol. 18, (10) : 888-893
Martinez, Nancy E.; Zimmermann, Tobias J.; Goosmann, Christian; et al.
2017
Palladium-Mediated Approach to Coumarin-Functionalized Amino Acids
Organic Letters
, American Chemical Society (ACS) 2017, Vol. 19, (11) : 2797-2800
Moodie, Lindon W. K.; Chammaa, Samy; Kindahl, Tomas; et al.
2016
Unraveling the Phosphocholination Mechanism of the Legionella pneumophila Enzyme AnkX
Biochemistry
, American Chemical Society (ACS) 2016, Vol. 55, (31) : 4375-4385
Gavriljuk, Konstantin; Schartner, Jonas; Seidel, Hans; et al.
2016
Activity-Based Proteome Profiling Probes Based on Woodward's Reagent K with Distinct Target Selectivity
Angewandte Chemie International Edition
, Vol. 55, (27) : 7766-7771
Qian, Yong; Schuermann, Marc; Janning, Petra; et al.
2016
The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signaling and gene expression of Legionella pneumophila
Molecular Microbiology
, Wiley-Blackwell 2016, Vol. 99, (4) : 778-793
Schell, Ursula; Simon, Sylvia; Sahr, Tobias; et al.
2015
Molecular perspectives on protein adenylylation
ACS Chemical Biology
, American Chemical Society (ACS) 2015, Vol. 10, (1) : 12-21
Hedberg, Christian; Itzen, Aymelt
2015
Enzymatic phosphocholination as a tool for protein labeling
The FEBS Journal
, Vol. 282 : 12-12
Heller, K; Ochtrop, Philipp; Albers, Michael; et al.
2015
Covalent Protein Labeling by Enzymatic Phosphocholination
Angewandte Chemie International Edition
, Vol. 54, (35) : 10327-10330
Heller, Katharina; Ochtrop, Philipp; Albers, Michael F.; et al.
2015
A Concise Total Synthesis of Breitfussin A and B
Organic Letters
, Vol. 17, (1) : 122-125
Pandey, Sunil Kumar; Guttormsen, Yngve; Haug, Bengt Erik; et al.
2015
Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway
PLoS Pathogens
, Vol. 11, (12)
Simon, Sylvia; Schell, Ursula; Heuer, Natalie; et al.
Exploring the substrate scope of the phosphocholine transferase AnkX for versatile protein functionalisation
Ochtrop, Philipp; Ernst, Stefan; Itzen, Aymelt; et al.
Identification of cellular protein targets for the
Legionella pneumophila
phosphocholinating effector AnkX
Ochtrop, Philipp; Swart, Leonie; Simon, Sylvia; et al.
Visa publikationer i DiVA
Forskargrupper
Forskningsledare
Christian Hedberg Lab
Forskningsprojekt
1 januari 2020 till 31 december 2023
Undersökande av bakteriella toxiner substratspecificitet via reaktivt protein – proteom profilering, RP3
1 januari 2020 till 31 december 2022
CryptO – Selektiv kemoterapi mot kryptosporidios i idisslare
Publicerad: 10 sep, 2020
Ett steg mot förbättrad förståelse för bakteriella sjukdomar
Publicerad: 21 nov, 2019
Drygt 28 miljoner kronor i anslag från Formas
Publicerad: 06 nov, 2019
52 VR-miljoner till forskning inom naturvetenskap och teknik
+ Visa mer
- Visa mindre