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Staff photo Christina West

Christina West

I am Associate Professor and Senior Consultant in Pediatric Allergy and Immunology. My research focuses on how environmental exposures in early life affect the development of allergy and asthma.

Contact

E-mail

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Affiliation
Associate professor, senior consultant (attending) physician at Department of Clinical Sciences Units: Pediatrics
Location
Umeå universitet, Klinisk vetenskap, 901 85 Umeå

I lead the multidisciplinary SYMBIO group and the purpose of our research is to increase the understanding of how environmental exposures in fetal life and childhood affect the development of non-communicable diseases, focusing on allergy and asthma.

Our goal is to identify predictive biomarkers and to develop targeted interventions for the prevention and treatment of allergic diseases. To reach that goal, we conduct epidemiological studies, randomized controlled clinical trials and mechanistic studies with a specific focus on the interaction between nutrition and microbiota in the gastrointestinal tract and their importance for immune system development and health outcomes. The research is mainly funded by the Swedish Research Council, the Swedish Heart-Lung Foundation, Region Västerbotten's Spearhead Funding and Central ALF, and the Ekhaga Foundation.

Projects
In the prospective epidemiological population based birth cohort study NorthPop www.northpop.se we study, among other things, the importance of early colonization patterns and dietary factors for allergy risk in the child. In the randomized controlled multicenter study “Restoration of Microbiota in Newborns” www.romans-studien.se, we investigate whether the controlled transfer of maternal bacteria to infants born by Caesarean section will restore the normal colonization patterns. We also study whether this intervention will reduce the child's risk of developing allergic diseases. In the randomized controlled multicenter study “Swedish study of immunotherapy of milk allergy in children” (SWITCH) we evaluate a Swedish protocol for oral immunotherapy with milk for the development of tolerance in children and adolescents with milk allergy.

SYMBIO team (PI West):
Dr Kotryna Simonyté Sjödin
Dr Andreas Sjödin
Dr Anna Winberg
Dr Åsa Strinnholm
Jonas Österlund, PhD student
Solveig Röisgård, PhD student
Carina Lagerqvist, Biomedical technician
Mona Svensson, Biomedical technician
 
I am co-director of the infrastructure NorthPop, see www.northpop.se, for information on ongoing projects and collaborators.

Collaborators in the RoMaNs project:
Professor Lars Engstrand, Karolinska institutet
Professor Maria Jenmalm, Linköping University
Dr Maria Jonsson, Uppsala University
Dr Emma Fransson, Karolinska institutet
Professor Ingrid Mogren, Umeå University
Dr Anna-Carin Wihlbäck, Umeå University
Dr Sophia Holmlund, Umeå University
  
Collaborators in the SWITCH project:
Docent Caroline Nilsson, Karolinska institutet
Docent Anna Nopp, Karolinska institutet
Professor Lennart Nilsson, Linköping University
Dr Emma Goksör, Gothenburg University

Collaborators Odontology, Umeå University:
Docent Pernilla Lif Holgersson
Senior professor Ingegerd Johansson
Dr Pamela Hasslöf
Dr Anders Esberg

BMC Pregnancy and Childbirth, BioMed Central 2021, Vol. 21, (1)
Meander, Lina; Lindqvist, Maria; Mogren, Ingrid; et al.
Scientific Reports, Nature Publishing Group 2020, Vol. 10, (1)
Lif Holgerson, Pernilla; Esberg, Anders; Sjödin, Andreas; et al.
Clinical and Translational Allergy, BioMed Central 2019, Vol. 9
Fox, Adam T.; Wopereis, Harm; Van Ampting, Marleen T. J.; et al.
Allergy. European Journal of Allergy and Clinical Immunology, John Wiley & Sons 2019, Vol. 74, (1) : 176-185
Simonyté Sjödin, Kotryna; Hammarström, Marie-Louise; Rydén, Patrik; et al.
Gut, BMJ Publishing Group Ltd 2019, Vol. 68, (11)
Sjödin, Kotryna Simonyte; Domellöf, Magnus; Lagerqvist, Carina; et al.
Clinical and Translational Allergy, BMC 2019, Vol. 9
Wopereis, Harm; van Ampting, Marleen T. J.; Cetinyurek-Yavuz, Aysun; et al.
Acta Paediatrica, John Wiley & Sons 2019, Vol. 108, (2) : 314-320
Österlund, J.; Winberg, Anna; West, C. E.
Pediatric Research, Vol. 83, (3) : 677-686
Candy, David C. A.; Van Ampting, Marleen T. J.; Nijhuis, Manon M. Oude; et al.
Nutrients, MDPI 2018, Vol. 10, (9)
Gustafsson, Anna; Granström, Elisabeth; Stecksén-Blicks, Christina; et al.
Allergy. European Journal of Allergy and Clinical Immunology, John Wiley & Sons 2017, Vol. 72 : 102-103
Fox, A. T.; Wopereis, H.; Van Ampting, M. T.; et al.
Internal medicine journal (Print), John Wiley & Sons 2017, Vol. 47 : 15-15
Fox, A.; van Ampting, M.; Nijhuis, M. O.; et al.
Food and Nutrition Sciences, Scientific Research Publishing 2017, (8) : 99-109
Hasslöf, Pamela; Karlsson Videhult, Frida; Silfverdal, Sven Arne; et al.
World Allergy Organization Journal, BIOMED CENTRAL LTD 2017, Vol. 10
Prescott, Susan L.; Larcombe, Danica-Lea; Logan, Alan C.; et al.
Scientific Reports, Nature Publishing Group 2017, Vol. 7
Slupsky, Carolyn M.; He, Xuan; Hernell, Olle; et al.
Journal of Allergy and Clinical Immunology, MOSBY-ELSEVIER 2017, Vol. 139, (1) : 232-245
Stray-Pedersen, Asbjorg; Sorte, Hanne Sormo; Samarakoon, Pubudu; et al.
Pediatric Research, NATURE PUBLISHING GROUP 2017, Vol. 81, (5) : 752-758
Szajewska, Hania; Ruszczynski, Marek; Szymanski, Henryk; et al.
PLoS ONE, Vol. 12, (1)
Timby, Niklas; Domellöf, Magnus; Lif Holgerson, Pernilla; et al.
Annals of Nutrition and Metabolism, KARGER 2017, Vol. 70 : 47-54
West, Christina
Allergology International, JAPANESE SOCIETY ALLERGOLOGY 2017, Vol. 66, (4) : 529-538
West, Christina E.; Dzidic, Majda; Prescott, Susan L.; et al.
Pediatric Research, Nature Publishing Group 2017, Vol. 82, (1) : 63-71
West, Christina E.; Kvistgaard, Anne Staudt; Peerson, Janet M.; et al.
Journal of Allergy and Clinical Immunology, MOSBY-ELSEVIER 2017, Vol. 139, (2) : AB53-AB53
Wopereis, Harm; Van Ampting, Marleen; Candy, David C. A.; et al.
Clinical and Experimental Allergy, Wiley-Blackwell 2016, Vol. 46, (12) : 1506-1521
Forsberg, A.; West, Christina E.; Prescott, S. L.; et al.
Current opinion in clinical nutrition and metabolic care, Vol. 19, (3) : 208-213
Karlsson Videhult, Frida; West, Christina E.
Clinical and Experimental Allergy, Vol. 46, (2) : 308-316
Metcalfe, J. R.; D'Vaz, N.; Makrides, M.; et al.
Current Opinion in Allergy and Clinical Immunology, Vol. 16, (4) : 390-395
Sjödin, Kotryna Simonyte; Vidman, Linda; Rydén, Patrik; et al.
Food & Nutrition Research, Vol. 60
Videhult, Frida K.; Öhlund, Inger; Hernell, Olle; et al.
Beneficial Microbes, Vol. 7, (2) : 171-179
West, Christina E.
Expert Review Of Clinical Immunology, Taylor & Francis 2016, Vol. 12, (6) : 625-639
West, Christina E.; Jenmalm, Maria C.; Kozyrskyj, Anita L.; et al.
Acta Paediatrica, Vol. 105, (2) : 206-214
Winberg, Anna; West, Christina; Strinnholm, Åsa; et al.
International Journal of Food Sciences and Nutrition, Taylor & Francis Group 2015, Vol. 66, (6) : 686-691
Karlsson Videhult, Frida; Andersson, Yvonne; Öhlund, Inger; et al.
European Journal of Nutrition, Vol. 54, (3) : 355-363
Karlsson Videhult, Frida; Öhlund, Inger; Stenlund, Hans; et al.
Mycoses (Berlin), Vol. 58, (9) : 550-556
Stecksén-Blicks, Christina; Granström, Elisabeth; Silfverdal, Sven Arne; et al.
Clinical and Experimental Allergy, Vol. 45, (1) : 43-53
West, Christina E.; Jenmalm, M. C.; Prescott, S. L.
Journal of Pediatric Gastroenterology and Nutrition - JPGN, Vol. 61, (2) : 157-158
West, Christina E.; Jenmalm, Maria C.
Journal of Allergy and Clinical Immunology, Vol. 135, (1) : 3-14
West, Christina E; Renz, Harald; Jenmalm, Maria C; et al.
Clinical and Experimental Allergy, Vol. 45, (9) : 1419-1429
West, Christina E.; Ryden, Patrik; Lundin, D.; et al.
Allergy. European Journal of Allergy and Clinical Immunology, Vol. 70 : 598-599
Winberg, Anna; West, Christina E.; Strinnholm, A.; et al.
PLoS ONE, Vol. 10, (7)
Winberg, Anna; West, Christina E.; Strinnholm, Åsa; et al.
Allergy. European Journal of Allergy and Clinical Immunology, Vol. 70 : 266-267
Winberg, Anna; West, Christina E.; Strinnholm, Åsa; et al.
Acta Paediatrica, Vol. 103, (12) : 1290-1296
Strinnholm, Åsa; Winberg, Anna; West, Christina; et al.
Current opinion in clinical nutrition and metabolic care, Vol. 17, (3) : 261-266
West, Christina E.
Clinical and Translational Allergy, BioMed Central 2014, Vol. 4
Winberg, Anna; Strinnholm, Åsa; Hedman, Linnea; et al.
Allergy. European Journal of Allergy and Clinical Immunology, Wiley-Blackwell 2014, Vol. 69, (Supplement: 99) : 151-151
Winberg, Anna; Strinnholm, Åsa; Hedman, Linnéa; et al.
British Journal of Nutrition, Cambridge University Press 2013, Vol. 110, (1) : 116-126
Chorell, Elin; Videhult, Frida Karlsson; Hernell, Olle; et al.
Caries Research, Karger 2013, Vol. 47, (6) : 559-565
Hasslöf, Pamela; West, Christina; Karlsson Videhult, Frida; et al.
British Journal of Nutrition, Vol. 109, (Suppplement 2) : S70-S75
Hernell, Olle; West, Christina E.
Allergy. European Journal of Allergy and Clinical Immunology, Wiley-Blackwell 2013, Vol. 68, (Special issue, supplement 97) : 17-17
Palmer, D. J.; Metcalfe, J.; Makrides, M.; et al.
Journal of Allergy and Clinical Immunology, Vol. 132, (2) : 387-392
Palmer, Debra J.; Metcalfe, Jessica; Makrides, Maria; et al.
Acta Paediatrica, Hoboken, NJ, USA: Wiley-Blackwell 2013, Vol. 102, (6) : 644-649
Persson, Karin; Öhlund, Inger; Nordström, Lisbeth; et al.