The oral microflora of health and disease - a side study of the longitudinal NorthPop study
The NorthPop project is a population-based longitudinal study in Västerbotten County, which aims to investigate early events/exposure effects on cognitive development and health in children from childbirth to school age. In a side study to NorthPop, the oral health of the children and their parents in relation to the general NorthPop results will be studied.
Recently, interest in the health and disease of the gastrointestinal (GI) microflora has increased, and studies show that intestinal microflora can affect metabolic and immunological events through cell signaling or transfer of bacteria or their metabolites to the circulation. There are also studies indicating that the oral microflora, which plays a central role for caries (the most common disease we see in the oral cavity of children), may play a part in the development of immune response and metabolic status with effects on our physiology beyond local oral effects.