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Umeå University
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Staff photo Daniel Öhlund

Daniel Öhlund

M.D, Ph.D., Associate Professor and Consultant Oncologist

Docent in oncology

Wallenberg Molecular Medicine Fellow

Wallenberg Clinical Fellow

Research qualifications: Docent
0000-0002-5847-2778

Contact

E-mail
daniel.ohlund@umu.se
Phone
+46 90 785 17 27, +46 70 555 40 86

Works as

Affiliation
Associate professor, consultant (attending) physician at Department of Diagnostics and Intervention Section: Oncology
Location
Visiting address, view map
Advancing pancreatic cancer research and therapeutics: the transformative role of organoid technology
Experimental and Molecular Medicine, Springer Nature 2025, Vol. 57, (1) : 50-58
Xu, Jihao; Pham, Minh Duc; Corbo, Vincenzo; et al.
High prevalence of pancreatic steatosis in pancreatic cancer patients: a meta-analysis and systematic review
Pancreatology (Print), Elsevier 2025, Vol. 25, (1) : 98-107
Vlăduț, Cătălina; Steiner, Corinna; Löhr, Matthias; et al.
Intratumoural expression of dihydropyrimidine dehydrogenase is an independent prognostic factor in resected pancreatic ductal adenocarcinoma treated with adjuvant gemcitabine
Oncology Letters, Spandidos Publications 2025, Vol. 29, (2)
Blomstrand, Hakon; Bodarve, Malin; Groth, Fredrik; et al.
Can our experience with surveillance for inherited pancreatic cancer help to identify early pancreatic cancer in the general population?
Familial Cancer, Springer Nature 2024, Vol. 23, (3) : 399-403
Löhr, J.-Matthias; Öhlund, Daniel; Söreskog, Emma; et al.
Metabolomics for early pancreatic cancer detection in plasma samples from a Swedish prospective population-based biobank
Journal of Gastrointestinal Oncology, AME Publishing Company 2024, Vol. 15, (2) : 755-767
Borgmästars, Emmy; Jacobson, Sara; Simm, Maja; et al.
Neoadjuvant FOLFIRINOX versus upfront surgery for resectable pancreatic head cancer (NORPACT-1): a multicentre, randomised, phase 2 trial
The Lancet Gastroenterology & Hepatology, Elsevier 2024, Vol. 9, (3) : 205-217
Labori, Knut Jørgen; Bratlie, Svein Olav; Andersson, Bodil; et al.
Overcoming therapy resistance in pancreatic cancer: new insights and future directions
Biochemical Pharmacology, Elsevier 2024, Vol. 229
Espona-Fiedler, Margarita; Patthey, Cedric; Lindblad, Stina; et al.
Scribble deficiency promotes pancreatic ductal adenocarcinoma development and metastasis
Cancer Research, American Association For Cancer Research (AACR) 2024, Vol. 84, (18) : 2968-2984
Bermejo-Rodriguez, Camino; Araos Henríquez, Joaquín; Caligiuri, Giuseppina; et al.
A new G-quadruplex-specific photosensitizer inducing genome instability in cancer cells by triggering oxidative DNA damage and impeding replication fork progression
Nucleic Acids Research, Oxford University Press 2023, Vol. 51, (12) : 6264-6285
Deiana, Marco; Andrés Castán, José María; Josse, Pierre; et al.
Dysregulation of core neurodevelopmental pathways: a common feature of cancers with perineural invasion
Frontiers in Genetics, Frontiers Media S.A. 2023, Vol. 14
Gonzalez-Castrillon, Luz Maria; Wurmser, Maud; Öhlund, Daniel; et al.
Extracellular galectin 4 drives immune evasion and promotes T-cell apoptosis in pancreatic cancer
Cancer immunology research, American Association for Cancer Research 2023, Vol. 11, (1) : 72-92
Lidström, Tommy; Cumming, Joshua; Gaur, Rahul; et al.
Key aspects for conception and construction of co-culture models of tumor-stroma interactions
Frontiers in Bioengineering and Biotechnology, Frontiers Media S.A. 2023, Vol. 11
Mason, James E.; Öhlund, Daniel
LAMC2 regulates key transcriptional and targetable effectors to support pancreatic cancer growth
Clinical Cancer Research, American Association for Cancer Research (AACR) 2023, Vol. 29, (6) : 1137-1154
Erice, Oihane; Narayanan, Shruthi; Feliu, Iker; et al.
The effect of side chain variations on quinazoline-pyrimidine G-quadruplex DNA ligands
European Journal of Medicinal Chemistry, Elsevier 2023, Vol. 248
Bhuma, Naresh; Chand, Karam; Andréasson, Måns; et al.
A cross-sectional and longitudinal analysis of pre-diagnostic blood plasma biomarkers for early detection of pancreatic cancer
International Journal of Molecular Sciences, MDPI 2022, Vol. 23, (21)
Mason, James E.; Lundberg, Erik; Jonsson, Pär; et al.
FcγRIIIa receptor interacts with androgen receptor and PIP5K1α to promote growth and metastasis of prostate cancer
Molecular Oncology
Flodbring Larsson, Per; Karlsson, Richard; Sarwar, Martuza; et al.
Circulating tissue polypeptide-specific antigen in pre-diagnostic pancreatic cancer samples
Cancers, MDPI 2021, Vol. 13, (21)
Borgmästars, Emmy; Lundberg, Erik; Öhlund, Daniel; et al.
Targeting Tumor-Stromal Interactions in Pancreatic Cancer: Impact of Collagens and Mechanical Traits
Frontiers in Cell and Developmental Biology, Frontiers Media S.A. 2021, Vol. 9
Maneshi, Parniyan; Mason, James; Dongre, Mitesh; et al.
Cancer cell-derived matrisome proteins promote metastasis in pancreatic ductal adenocarcinoma
Cancer Research, The American Association for Cancer Research 2020, Vol. 80, (7) : 1461-1474
Tian, Chenxi; Öhlund, Daniel; Rickelt, Steffen; et al.
Ex Vivo Organoid Cultures Reveal the Importance of the Tumor Microenvironment for Maintenance of Colorectal Cancer Stem Cells
Cancers, MDPI 2020, Vol. 12, (4)
Li, Xingru; Larsson, Pär; Ljuslinder, Ingrid; et al.
Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G-Quadruplex Stabilization
Journal of the American Chemical Society, Vol. 142, (6) : 2876-2888
Jamroskovic, Jan; Doimo, Mara; Chand, Karam; et al.
Recent Discoveries of Diagnostic, Prognostic and Predictive Biomarkers for Pancreatic Cancer
Cancers, MDPI 2020, Vol. 12, (11)
Khomiak, Andrii; Brunner, Marius; Kordes, Maximilian; et al.
CA19-9 and apolipoprotein-A2 isoforms as detection markers for pancreatic cancer: a prospective evaluation
International Journal of Cancer, Wiley-Blackwell 2019, Vol. 144, (8) : 1877-1887
Honda, Kazufumi; Katzke, Verena A.; Hüsing, Anika; et al.
Identification of resistance pathways specific to malignancy using organoid models of pancreatic cancer
Clinical Cancer Research, American Association for Cancer Research Inc. 2019, Vol. 25, (22) : 6742-6755
Ponz-Sarvise, Mariano; Corbo, Vincenzo; Tiriac, Hervé; et al.
Novel prognostic markers within the CD44-stromal ligand network in pancreatic cancer
Journal of Pathology, John Wiley & Sons 2019, Vol. 5, (2) : 130-141
Franklin, Oskar; Billing, Ola; Öhlund, Daniel; et al.
Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences 2019, Vol. 116, (39) : 19609-19618
Tian, Chenxi; Clauser, Karl R.; Öhlund, Daniel; et al.
Stromal biology and therapy in pancreatic cancer: ready for clinical translation?
Gut, BMJ Publishing Group Ltd 2019, Vol. 68, (1) : 159-171
Neesse, Albrecht; Bauer, Christian Alexander; Öhlund, Daniel; et al.
Plasma micro-RNA alterations appear late in pancreatic cancer
Annals of Surgery, Vol. 267, (4) : 775-781
Franklin, Oskar; Jonsson, Pär; Billing, Ola; et al.
VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival
Journal of Pathology, John Wiley & Sons 2018, Vol. 246, (3) : 311-322
Morin, Eric; Sjöberg, Elin; Tjomsland, Vegard; et al.
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
Journal of Experimental Medicine, Vol. 214, (3) : 579-596
Öhlund, Daniel
NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer
Cell, Vol. 166, (4) : 936-976
Chio, Iok In Christine; Jafarnejad, Seyed Mehdi; Ponz-Sarvise, Mariano; et al.
Combining conventional and stroma-derived tumour markers in pancreatic ductal adenocarcinoma
Cancer Biomarkers, IOS Press 2015, Vol. 15, (1) : 1-10
Franklin, Oskar; Öhlund, Daniel; Lundin, Christina; et al.
Organoid models of human and mouse ductal pancreatic cancer
Cell, Cell press 2015, Vol. 160, (1-2) : 324-338
Boj, Sylvia F; Hwang, Chang-Il; Baker, Lindsey A; et al.
Fibroblast heterogeneity in the cancer wound
Journal of Experimental Medicine, Vol. 211, (8) : 1503-1523
Öhlund, Daniel; Elyada, Ela; Tuveson, David
Type IV collagen stimulates pancreatic cancer cell proliferation, migration, and inhibits apoptosis through an autocrine loop
BMC Cancer, Vol. 13
Öhlund, Daniel; Franklin, Oskar; Lundberg, Erik; et al.
Type IV collagen is a tumour stroma-derived biomarker for pancreas cancer
British Journal of Cancer, Vol. 101, (1) : 91-97
Öhlund, Daniel; Lundin, Christina; Ardnor, Bjarne; et al.
Expression pattern and circulating levels of endostatin in patients with pancreas cancer
International Journal of Cancer, Vol. 122, (12) : 2805-2810
Öhlund, Daniel; Ardnor, Bjarne; Öman, Mikael; et al.
View publications in DiVA

Research groups

Head of research
Daniel Öhlund Lab
A challenge to find the solution to pancreatic cancer

Pancreatic cancer can resist most existing treatments and the five-year survival rate is low.