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Staff photo Erik Chorell

Erik Chorell

I work as associate professor at the Department of Chemistry, which includes research, teaching and infrastructure responsibility linked to Life Science and chemical biology.

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Affiliation
Associate professor at Department of Chemistry
Location
KB.C3, Linnaeus väg 10, (rum: B3.05.09) Umeå universitet, 901 87 Umeå

I have a background in organic chemistry/medicinal chemistry with a post doc in molecular biology and a post doc in biophysical chemistry. Throughout my background I have focused on the development of small bioactive molecules, often linked to new therapeutic strategies. I am now associate professor and docent at Umeå University with the following main areas:

My research focuses primarily on developing small molecules that can affect biological systems linked primarily to cancer. We use these molecules both to study the biological systems from a basic research perspective, but they are also interesting as starting points for drug development. In addition to small molecules, we also use other strategies such as oligonucleotides to affect biological systems. A major focus area in the lab is G-quadruplex DNA structures and how our strategies can be used to bind these DNA structures and thereby influence gene expression of proteins linked to diseases such as cancer. Read more about the research in my lab.

I teach in organic chemistry/pharmaceutical chemistry/chemical biology and am also responsible for the bachelor of science programme in Life Science. The programme combines courses in chemistry and molecular biology and is one of the only life-science programmes in Sweden. Life science is an area that is developing very strongly with both many new companies and strong research. Sweden also has a national life science strategy with the goal of being a leading life-science nation, so it is very inspirational to lead an education program in this particular area!

In addition to research and teaching, I am also responsible for the UmU node of the Chemical Biology Consortium Sweden (CBCS). CBCS is a national infrastructure that is also part of  SciLifeLab with the goal of helping researchers identify and develop bioactive small molecules. Researchers searching for the infrastructure often have a biological process or phenotype they are interested in. We help the researchers develop test systems (assays), and screen our libraries of small molecules (we have over 200 000 small molecules in total). We can also further develop identified molecules as well as run projects that do not include screening, see more on CBCS:s website. The infrastructure is financed by the host universities, SciLifeLab and from 2022 also by the Swedish Research Council.

Chemical Science, Royal Society of Chemistry 2022, Vol. 13, (8) : 2347-2354
Prasad, Bagineni; Doimo, Mara; Andréasson, Måns; et al.
Book of abstracts: 9th European Variety in University Chemistry Education Conference EUROVARIETY 2021, University of Ljubljana 202160
Broman, Karolina; Chorell, Erik; Holmboe, Michael
Den 8:e utvecklingskonferensen för Sveriges ingenjörsutbildningar: Detaljerat program
Broman, Karolina; Chorell, Erik; Holmboe, Michael
Universitetspedagogiskakonferensen 2021: den goda utbildningsmiljön 2.1, Umeå: Universitetspedagogik och lärandestöd (UPL), Umeå universitet 2021 : 12-13
Broman, Karolina; Chorell, Erik; Holmboe, Michael; et al.
ACS Chemical Biology, American Chemical Society (ACS) 2021, Vol. 16, (8) : 1365-1376
Deiana, Marco; Obi, Ikenna; Andréasson, Måns; et al.
Chemical Science, Royal Society of Chemistry 2020, Vol. 11, (38) : 10529-10537
Das, Rabindra Nath; Andréasson, Måns; Kumar, Rajendra; et al.
Nanoscale, Royal Society of Chemistry 2020, Vol. 12, (24) : 12950-12957
Deiana, Marco; Chand, Karam; Jamroskovic, Jan; et al.
Angewandte Chemie International Edition, Wiley-VCH Verlagsgesellschaft 2020, Vol. 59, (2) : 896-902
Deiana, Marco; Chand, Karam; Jamroskovic, Jan; et al.
Journal of the American Chemical Society, Vol. 142, (6) : 2876-2888
Jamroskovic, Jan; Doimo, Mara; Chand, Karam; et al.
Nucleic Acids Research, Oxford University Press 2020, Vol. 48, (3) : 1108-1119
Kumar, Rajendra; Chand, Karam; Bhowmik, Sudipta; et al.
Nucleic Acids Research, Oxford University Press 2020, Vol. 48, (19) : 10998-11015
Obi, Ikenna; Rentoft, Matilda; Singh, Vandana; et al.
Chemistry - A European Journal, Wiley-VCH Verlagsgesellschaft 2020, Vol. 26, (43) : 9561-9572
Prasad, Bagineni; Das, Rabindra Nath; Jamroskovic, Jan; et al.
7:e Utvecklingskonferensen för Sveriges ingenjörsutbildningar
Broman, Karolina; Mårell-Olsson, Eva; Johnels, Dan; et al.
Proceedings of the National Academy of Sciences of the United States of America, The National Academy of Scionces of the United States of America 2019, Vol. 116, (21) : 10510-10517
Flentie, Kelly; Harrison, Gregory A.; Tükenmez, Hasan; et al.
DNA Repair, Vol. 82
Jamroskovic, Jan; Obi, Ikenna; Movahedi, Anahita; et al.
International Journal of Biological Macromolecules, Elsevier 2018, Vol. 118 : 629-639
Bhattacharjee, Snehasish; Chakraborty, Sandipan; Chorell, Erik; et al.
Chemistry - A European Journal, Wiley-VCH Verlagsgesellschaft 2018, Vol. 24, (31) : 7926-7938
Prasad, Bagineni; Jamroskovic, Jan; Bhowmik, Sudipta; et al.
ChemistrySelect, John Wiley & Sons 2017, Vol. 2, (11) : 3293-3296
Kumar, Vipan; Chand, Karam; Chorell, Erik
Organic and biomolecular chemistry, Royal Society of Chemistry 2017, Vol. 15, (15) : 3265-3275
Livendahl, Madeleine; Jamroskovic, Jan; Hedenström, Mattias; et al.
PLOS ONE, Vol. 12, (9)
Pokrzywa, Malgorzata; Pawelek, Katarzyna; Kucia, Weronika Elzbieta; et al.
Cell chemical biology, Vol. 23, (3) : 404-414
Good, James A. D.; Andersson, Christopher; Hansen, Sabine; et al.
Chemistry - A European Journal, Vol. 22, (52) : 18932-18943
Jamroskovic, Jan; Livendahl, Madeleine; Eriksson, Jonas; et al.
Chemistry - A European Journal, Vol. 22, (37) : 13004-13009
Livendahl, Madeleine; Jamroskovic, Jan; Ivanova, Svetlana; et al.
Parkinson's Disease, Vol. 1
Chermenina, Maria; Chorell, Erik; Pokrzywa, Malgorzata; et al.
PLOS ONE, Vol. 10, (10) : 1-11
Chorell, Erik; Andersson, Emma; Evans, Margery L.; et al.
mBio, Vol. 6, (1)
Engström, Patrik; Krishnan, K. Syam; Ngyuen, Bidong D.; et al.
Molecular Cell, Vol. 57, (3) : 445-455
Evans, Margery L.; Chorell, Erik; Taylor, Jonathan D.; et al.
Scientific Reports, Nature Publishing Group 2015, Vol. 5
Sharma, Sandeep K; Chorell, Erik; Steneberg, Pär; et al.
Biochemical and Biophysical Research Communications - BBRC, Vol. 466, (2) : 192-195
Sharma, Sandeep K.; Chorell, Erik; Wittung-Stafshede, Pernilla
Organic Letters, American Chemical Society (ACS) 2015, Vol. 17, (24) : 6194-6197
Singh, Pardeep; Chorell, Erik; Krishnan, K Syam; et al.
Organic and biomolecular chemistry, Vol. 12, (12) : 1942-1956
Dang, Hung The; Chorell, Erik; Uvell, Hanna; et al.
mBio, Vol. 5, (6) : UNSP e02038-
Greene, Sarah E.; Pinkner, Jerome S.; Chorell, Erik; et al.
European Journal of Organic Chemistry, (28) : 6175-6182
Kindahl, Tomas; Chorell, Elin; Chorell, Erik
Organic and biomolecular chemistry, Vol. 12, (25) : 4461-4470
Kindahl, Tomas; Chorell, Erik
Chemistry and Biology, Elsevier 2013, Vol. 20, (10) : 1245-1254
Andersson, Emma K.; Bengtsson, Christoffer; Evans, Margery L.; et al.
Abstracts of Papers of the American Chemical Society, Vol. 245
Bengtsson, Christoffer; Chorell, Erik; Krishnan, Syam; et al.
European Journal of Organic Chemistry, Wiley-VCH Verlagsgesellschaft 2013, Vol. 2013, (33) : 7512-7516
Chorell, Erik; Chorell, Elin
Journal of Organic Chemistry, American Chemical Society (ACS) 2013, Vol. 78, (23) : 12207-12213
Krishnan, K. Syam; Bengtsson, Christoffer; Good, James A. D.; et al.
Bioorganic & Medicinal Chemistry, Elsevier 2012, Vol. 20, (9) : 3128-3142
Chorell, Erik; Pinkner, Jerome S; Bengtsson, Christoffer; et al.
Chemistry - A European Journal, Berlin: Wiley-VCH Verlagsgesellschaft 2012, Vol. 18, (15) : 4522-4532
Chorell, Erik; Pinkner, Jerome S; Bengtsson, Christoffer; et al.
Journal of the American Chemical Society, American Chemical Society (ACS) 2012, Vol. 134, (7) : 3439-3444
Horvath, Istvan; Weise, Christoph F; Andersson, Emma K; et al.
European Journal of Medicinal Chemistry, Elsevier Masson SAS 2011, Vol. 46, (4) : 1103-1116
Chorell, Erik; Bengtsson, Christoffer; Sainte-Luce Banchelin, Thomas; et al.
Tetrahedron Letters, Elsevier Ltd 2010, Vol. 51, (18) : 2461-2463
Chorell, Erik; Edvinsson, Sofie; Almqvist, Fredrik
Journal of Medicinal Chemistry, Washington, USA: American Chemical Society 2010, Vol. 53, (15) : 5690-5695
Chorell, Erik; Pinkner, Jerome S; Phan, Gilles; et al.
Nature Chemical Biology, Nature Publishing Group 2009, Vol. 5, (12) : 913-919
Cegelski, Lynette; Pinkner, Jerome S; Hammer, Neal D; et al.
Bioorganic & Medicinal Chemistry Letters, Elsevier Ltd 2008, Vol. 18, (12) : 3536-3540
Åberg, Veronica; Das, Pralay; Chorell, Erik; et al.
Journal of Organic Chemistry, Washington, DC 20036, USA: American Chemical Society 2007, Vol. 72, (13) : 4917-4924
Chorell, Erik; Das, Pralay; Almqvist, Fredrik
Microwave-assisted synthesis of hetreocycles, Springer-Verlag 2006 : 1-30
Pemberton, Nils; Chorell, Erik; Almqvist, Fredrik
Organic and biomolecular chemistry, London, U.K.: Royal Society of Chemistry 2005, Vol. 3, (15) : 2817-2823
Åberg, Veronica; Norman, Fredrik; Chorell, Erik; et al.

Research groups

Head of research
Erik Chorell lab

Research projects

1 January 2022 until 31 December 2025