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Johan Henriksson

I am a researcher in T-cell biology and development of new methods (bioinformatics algorithms and wet lab protocols), with special emphasis on immunotherapy and CAR T cells.

Research qualifications: Docent

Works at

Research fellow at Department of Molecular Biology Section: Group Johan Henriksson
6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå

Our research group tries to understand how T cells function, in health and disease. T cells are particularly important against cancer, and genetically modified T cells (CAR T cells) is a promising therapy. We use our maps of gene regulation to develop new ways of programming T cells to fight diseases such as cancer.

To our aid we use modern unbiased measurement methods ("multi-omics" and single-cell) that helps us collect large amounts of information without deciding in advance which genes we should look at. As such we hope to obtain insights not possible with traditional targeted methods. Furthermore we use modern synthetic biology such as the CRISPR-Cas9 technology to reprogram genes, to be able to tell in detail how they function. We hope the genes we discover will be the key to hard-to-cure diseases such as cancer.

See our website for more information  as well as the MIMS website


Nature Communications, Springer Nature 2023, Vol. 14, (1)
Chotiwan, Nunya; Rosendal, Ebba; Willekens, Stefanie M. A.; et al.
Frontiers in Immunology, Frontiers Media S.A. 2023, Vol. 14
Hildebrandt, Franziska; Mohammed, Mubasher; Dziedziech, Alexis; et al.
Biophysical Reviews
Mihai, Ionut Sebastian; Chafle, Sarang; Henriksson, Johan
Microbiology Spectrum, American Society for Microbiology 2023, Vol. 11, (2)
Mohammed, Mubasher; Dziedziech, Alexis; Sekar, Vaishnovi; et al.
Nature Communications, Springer Nature 2023, Vol. 14
Pu, Longjun; Wang, Jing; Lu, Qiongxuan; et al.
Journal for ImmunoTherapy of Cancer, BMJ Publishing Group Ltd 2023, Vol. 11, (2)
Schoutrop, Esther; Poiret, Thomas; El-Serafi, Ibrahim; et al.
mBio, American Society for Microbiology 2022, Vol. 13, (3)
Rosendal, Ebba; Mihai, Ionut Sebastian; Becker, Miriam; et al.
Frontiers in Immunology, Frontiers Media S.A. 2021, Vol. 11
Dernstedt, Andy; Leidig, Jana; Holm, Anna; et al.
PLOS ONE, Public Library of Science (PLoS) 2021, Vol. 16, (5)
Haim-Vilmovsky, Liora; Henriksson, Johan; Walker, Jennifer A.; et al.
PLoS biology, Public Library of Science 2021, Vol. 19, (4)
Jafari, Shadi; Henriksson, Johan; Yan, Hua; et al.
Genes, mdpi 2021, Vol. 12, (2) : 1-13
Mihai, Ionut Sebastian; Das, Debojyoti; Maršalkaite, Gabija; et al.
PLOS ONE, Public Library of Science 2019, Vol. 14, (11)
Filcek, Kimberly; Vielfort, Katarina; Muraleedharan, Samada; et al.
Single cell method: sequencing and proteomics, Humana Press 2019 : 395-406
Henriksson, Johan

Bioinformatics and advanced molecular biology