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Staff photo Johan Henriksson

Johan Henriksson

I am a researcher in T-cell biology and development of new methods (bioinformatics algorithms and wet lab protocols), with special emphasis on immunotherapy and CAR T cells.

Contact

Works at

Affiliation
Research fellow at Department of Molecular Biology Units: Group Johan Henriksson
Location
6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå
Affiliation
Affiliated as research fellow at Molecular Infection Medicine Sweden (MIMS) Units: Research groups
Location
6L, Institutionen för molekylärbiologi Institutionen för molekylärbiologi, 90187 Umeå

Our rsearch group tries to understand how T cells function, in health and disease. T cells are particularly important against cancer, and genetically modified T cells (CAR T cells) is a promising therapy. We use our maps of gene regulation to develop new ways of programming T cells to fight diseases such as cancer.

To our aid we use modern unbiased measurement methods ("multi-omics" and single-cell) that helps us collect large amounts of information without deciding in advance which genes we should look at. As such we hope to obtain insights not possible with traditional targeted methods. Furthermore we use modern synthetic biology such as the CRISPR-Cas9 technology to reprogram genes, to be able to tell in detail how they function. We hope the genes we discover will be the key to hard-to-cure diseases such as cancer.

See our website for more information  

 

Frontiers in Immunology, Frontiers Media S.A. 2021, Vol. 11
Dernstedt, Andy; Leidig, Jana; Holm, Anna; et al.
Genes, mdpi 2021, Vol. 12, (2) : 1-13
Mihai, Ionut Sebastian; Das, Debojyoti; Maršalkaite, Gabija; et al.
PLoS ONE, Public Library of Science 2019, Vol. 14, (11)
Filcek, Kimberly; Vielfort, Katarina; Muraleedharan, Samada; et al.

Research groups

Head of research
Johan Henriksson Group

Bioinformatics and advanced molecular biology