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Staff photo Silvia Remeseiro

Silvia Remeseiro

Wallenberg Molecular Medicine Fellow (WCMM).

Long-range Gene Regulation and 3D-organization of the Glioblastoma Genome

Contact

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Affiliation
Affiliation

Silvia Remeseiro was recruited in March 2019 from EMBL Heidelberg (Germany) to Umeå University as a Wallenberg Molecular Medicine Fellow. She is employed as an Associate senior lecturer at UCMM, Faculty of Medicine.

Biosketch:

"I obtained my PhD in 2012 at the Spanish National Cancer Research Center (CNIO, Madrid – Spain), one of the leading cancer research centers in Europe. There I focused on the study of cohesin-SA1 roles in telomere replication and transcriptional regulation in the context of cancer and development, during which time I also performed a stay at the Albert Einstein College of Medicine (AECOM) in New York (US). In May 2013, I was awarded a Marie Curie/EIPOD postdoctoral fellowship and joined the prestigious EMBL (European Molecular Biology Laboratory) in Heidelberg (Germany). My postdoc research aimed to define the crosstalk between the 3D topological architecture and the regulatory organisation of the genome. I studied how introducing structural perturbations in the genome affects the communication between gene promoters and distant enhancers, thus altering the transcriptional output and having an impact in cancer and development. At the end of my postdoc, I followed the lab when they moved to Institute Pasteur (Paris, France) to finalise my postdoctoral projects before moving to Umeå. Since March 2019 I am a Wallenberg Molecular Medicine Fellow at WCMM (Wallenberg Center for Molecular Medicine) and group leader at UCMM (Umeå Center for Molecular Medicine). My lab is mostly interested in studying the interplay between long-range gene regulation and the 3D chromatin organisation. At the moment our efforts are focused on mapping the enhancer landscape and promoter-enhancer interactome in Glioblastoma, the most aggressive but also the most common primary brain tumor in adults".

 

Cells, MDPI 2022, Vol. 11, (9)
Hörnblad, Andreas; Remeseiro, Silvia
BMC molecular and cell biology, BioMed Central 2021, Vol. 22, (1)
Dakhel, Soran; Davies, Wayne I. L.; Joseph, Justin V.; et al.
Scientific Reports, Nature Publishing Group 2021, Vol. 11, (1)
López-Pérez, Ana R.; Norlin, Stefan; Steneberg, Pär; et al.
Nature, Nature Publishing Group 2018, Vol. 553, (7689) : 515-520
Bahr, Carsten; von Paleske, Lisa; Uslu, Veli V; et al.
Wiley Interdisciplinary Reviews: Developmental Biology, Vol. 5, (2) : 169-185
Remeseiro, Silvia; Hörnblad, Andreas; Spitz, François

Research groups

Head of research
Silvia Remeseiro lab

Research projects

1 January 2022 until 31 December 2024
1 January 2020 until 31 December 2023