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Umeå universitet
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Huvudmenyn dold.
Personalbild Cecilia Koskinen Holm

Cecilia Koskinen Holm

Biträdande lektor och ST-tandläkare i käkkirurgi. Jag bedriver cellbiologisk forskning som rör sjukdomsprocesser i käkbenet och i den orala slemhinnan.

Pedagogisk meritering: Meriterad lärare

Kontakt

E-post
cecilia.koskinen@umu.se
Telefon
090-785 80 83

Verksam som

Anknytning
Biträdande universitetslektor, ST-tdl käkkirurgi vid Institutionen för odontologi Enhet: Tandläkarutbildningen, Parodontologi
Plats
Byggnad 5A; våning 5, Norrlands universitetssjukhus Umeå universitet, 901 85 Umeå

Som biträdande lektor har jag en kombinationsanställning där jag jobbar halvtid med forskning och undervisning och på den andra halvtiden specialistutbildar jag mig till käkkirurg. Min forskning fokuserar på de genmutationer som ligger bakom den sällsynta diagnosen parodontalt Ehlers-Danlos syndrom . Dessutom är jag involverad i projekt som studerar bencellers funktion vid normala tillstånd och vid sjukdomstillstånd

Jag undervisar framför allt på tandläkarprogrammet och undervisningen sträcker sig från benbiologi på de prekliniska terminerna till käkkirurgi på slutet av tandläkarutbildningen. Jag är också handledare för examensarbeten på grundutbildningen. Min kliniska tjänstgöring sker på käkkirurgiska kliniken, Neuro-huvud-hals-centrum (NHHC), Region Västerbotten.

Impact of a heterozygous c1rr301p/wt mutation on collagen metabolism and inflammatory response in human gingival fibroblasts
Cells, MDPI 2025, Vol. 14, (7)
Qu, Chengjuan; Koskinen Holm, Cecilia
The expression of signal regulatory protein alpha (SIRPα) in periodontal cells and tissue
Acta Odontologica Scandinavica, Medical Journals Sweden 2024, Vol. 83 : 486-492
Koskinen Holm, Cecilia; Rosendahl, Sara; Oldenborg, Per-Arne; et al.
Successful rehabilitation after multiple severe complications following orthognathic surgery: a case report
BMC Oral Health, BioMed Central (BMC) 2023, Vol. 23, (1)
Koskinen Holm, Cecilia; Johansson, Lena C.; Brundin, Malin; et al.
Engineering a 3D In Vitro Model of Human Gingival Tissue Equivalent with Genipin/Cytochalasin D
International Journal of Molecular Sciences, MDPI 2022, Vol. 23, (13)
Koskinen Holm, Cecilia; Qu, Chengjuan
Lack of CCR3 leads to a skeletal phenotype only in male mice
Biochemical and Biophysical Research Communications - BBRC, Vol. 620 : 98-104
Rosendahl, Sara; Sulniute, Rima; Persson, Julia; et al.
CCR3 deficiency is associated with increased osteoclast activity and reduced cortical bone volume in adult male mice
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2021, Vol. 296
Rosendahl, Sara; Sulniute, Rima; Eklund, Michaela; et al.
Innate lymphoid cells are present in gingivitis and periodontitis
Journal of Periodontology, Wiley-Blackwell 2019, Vol. 90, (2) : 200-207
Kindstedt, Elin; Holm, Cecilia Koskinen; Palmqvist, Py; et al.
Marginal jawbone loss is associated with onset of rheumatoid arthritis and is related to plasma level of receptor activator of nuclear factor kappa-B ligand
Scandinavian Journal of Rheumatology, Taylor & Francis 2018, Vol. 47 : 22-22
Johansson, L.; Kindstedt, Elin; Palmqvist, Py; et al.
Association between marginal jawbone loss and the onset of rheumatoid arhtritis and relationship to plasma levels of RANKL
Rheumatology, Oxford University Press 2018, Vol. 70, (4) : 508-515
Kindstedt, Elin; Johansson, Linda; Palmqvist, Py; et al.
Association between marginal jawbone loss and the onset of rheumatoid arhtritis and relationship to plasma levels of RANKL
Arthritis & Rheumatology, Wiley-Blackwell 2018, Vol. 70, (4) : 508-515
Kindstedt, Elin; Johansson, Linda; Palmqvist, Py; et al.
Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL) and Marginal Jawbone Loss Predates the Onset of Rheumatoid Arthritis
Arthritis & Rheumatology, Wiley-Blackwell 2017, Vol. 69
Kindstedt, Elin; Johansson, Linda; Palmqvist, Py; et al.
CCL11, a novel mediator of inflammatory bone resorption
Scientific Reports, Nature Publishing Group 2017, Vol. 7, (1)
Kindstedt, Elin; Koskinen Holm, Cecilia; Sulniute, Rima; et al.
Lack of SIRP alpha phosphorylation and concomitantly reduced SHP-2-PI3K-Akt2 signaling decrease osteoblast differentiation
Biochemical and Biophysical Research Communications - BBRC, Vol. 478, (1) : 268-273
Holm, Cecilia Koskinen; Engman, Sara; Sulniute, Rima; et al.
Increased Eotaxin and MCP-1 Levels in Serum from Individuals with Periodontitis and in Human Gingival Fibroblasts Exposed to Pro-Inflammatory Cytokines
PLOS ONE, Vol. 10, (8)
Boström, Elisabeth A.; Kindstedt, Elin; Sulniute, Rima; et al.
Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen
PLoS One, plos one 2015, Vol. 10, (7)
Kolan, Shrikant; Lejon, Kristina; Koskinen Holm, Cecilia; et al.
CD47–SIRPα: an interaction of importance for bone cell differentiation
Umeå University odontological dissertations, 132
Koskinen, Cecilia
Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein α (SIRPα) signaling
Journal of Biological Chemistry, Vol. 288, (41) : 29333-29344
Koskinen, Cecilia; Persson, Emelie; Baldock, Paul; et al.
Lack of CD47 leads to impaired bone cell differentiation and results in an osteopenic bone phenotype
Bone, Vol. 50, (Supplement 1) : S42-S43
Koskinen, Cecilia; Persson, Emma; Baldock, P.; et al.
Osteoclast formation is strongly reduced both in vivo and in vitro in the absence of CD47/SIRPalpha-interaction
Biochemical and Biophysical Research Communications - BBRC, Vol. 352, (2) : 444-448
Lundberg, Pernilla; Koskinen, Cecilia; Baldock, Paul A; et al.
Discovery of Innate Lymphoid Cells in Gingivitis and Periodontitis
Kindstedt, Elin; Koskinen Holm, Cecilia; Palmqvist, Py; et al.
Reduced SIRPα phosphorylation and concommitant SHP-2–PI3K–Akt2 signaling decrease osteoblast differentiation
Koskinen, Cecilia; Engman, Sara; Sulniute, Rima; et al.
Visa publikationer i DiVA
Cecilia Koskinen Holm
Cecilia Koskinen Holm: Bygga 3D-modell av munslemhinna – funkar det?

Med en 3D-modell av munnens slemhinna kan olika förändringar studeras.