Helena Lindgren

Kontakt

helena.e.lindgren@umu.se

090-785 87 87

Verksam vid

Första forskningsingenjör vid Institutionen för klinisk mikrobiologi Enhet: Klinisk bakteriologi

6B,, Universitetssjukhuset, 22B Umeå universitet, 901 85 Umeå

Kinetics of the serological response up to one year after tularemia

Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2023, Vol. 12

Lindgren, Helena; Eklund, Johan; Eneslätt, Kjell; et al.

Macrophages Demonstrate Guanylate-Binding Protein-Dependent and Bacterial Strain-Dependent Responses to Francisella tularensis

Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2021, Vol. 11

Mohammadi, Nasibeh; Lindgren, Helena; Yamamoto, Masahiro; et al.

Vaccine-Mediated Mechanisms Controlling Francisella tularensis SCHU S4 Growth in a Rat Co-Culture System

Pathogens, MDPI 2020, Vol. 9, (5)

Lindgren, Helena; Eneslätt, Kjell; Golovliov, Igor; et al.

Guanylate-Binding Proteins Are Critical for Effective Control of Francisella tularensis Strains in a Mouse Co-Culture System of Adaptive Immunity

Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2020, Vol. 10

Mohammadi, Nasibeh; Lindgren, Helena; Golovliov, Igor; et al.

Francisella tularensis: FupA mutation contributes to fluoroquinolone resistance by increasing vesicle secretion and biofilm formation

Emerging Microbes & Infections, Taylor & Francis 2019, Vol. 8, (1)

Siebert, Claire; Lindgren, Helena; Ferre, Sabrina; et al.

Lack of OxyR and KatG Results in Extreme Susceptibility of Francisella tularensis LVS to Oxidative Stress and Marked Attenuation In vivo

Frontiers in Cellular and Infection Microbiology, Vol. 7

Honn, Marie; Lindgren, Helena; Bharath, Gurram Kumar; et al.

IFN-gamma extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection

PLoS Pathogens, Public Library Science 2017, Vol. 13, (10)

Wallet, Pierre; Benaoudia, Sacha; Mosnier, Amandine; et al.

An In Vitro Co-culture Mouse Model Demonstrates Efficient Vaccine-Mediated Control of Francisella tularensis SCHU S4 and Identifies Nitric Oxide as a Predictor of Efficacy

Frontiers in Cellular and Infection Microbiology, Vol. 6

Golovliov, Igor; Lindgren, Helena; Eneslätt, Kjell; et al.

Gallium Potentiates the Antibacterial Effect of Gentamicin against Francisella tularensis

Antimicrobial Agents and Chemotherapy, Vol. 60, (1) : 288-295

Lindgren, Helena; Sjöstedt, Anders

Roles of Reactive Oxygen Species-Degrading Enzymes of Francisella tularensis SCHU S4

Infection and Immunity, Vol. 83, (6) : 2255-2263

Binesse, Johan; Lindgren, Helena; Lindgren, Lena; et al.

Mechanisms of heme utilization by Francisella tularensis

PLOS ONE, Vol. 10, (3)

Lindgren, Helena; Lindgren, Lena; Golovliov, Igor; et al.

The Rift Valley Fever virus protein NSm and putative cellular protein interactions

Virology Journal, Vol. 9 : 139-

Engdahl, Cecilia; Näslund, Jonas; Lindgren, Lena; et al.

The role of MglA for adaptation to oxidative stress of Francisella tularensis LVS

BMC Microbiology, London: BioMed Central 2012, Vol. 12 : 14-

Honn, Marie; Lindgren, Helena; Sjöstedt, Anders

Roles for wbtC, wbtI, and kdtA genes in lipopolysaccharide biosynthesis, protein glycosylation, virulence, and immunogenicity in Francisella tularensis strain SCHU S4

Pathogens, MDPI 2012, Vol. 1, (1) : 12-29

Twine, Susan M; Vinogradov, Evguenii; Lindgren, Helena; et al.

Iron content differs between Francisella tularensis subspecies tularensis and subspecies holarctica strains and correlates to their susceptibility to H(2)O(2)-induced killing

Infection and Immunity, Vol. 79, (3) : 1218-1224

Lindgren, Helena; Honn, Marie; Salomonsson, Emelie; et al.

Administration of a donor of nitric oxide inhibits mglA expression of intracellular Francisella tularensis and counteracts phagosomal escape and subversion of TNF-α secretion

Journal of Medical Microbiology, Vol. 30, (11) : 1570-1583

Tancred, Linda; Telepnev, Maxim; Golovlev, Igor; et al.

The 58-kilodalton major virulence factor of Francisella tularensis is required for efficient utilization of iron

Infection and Immunity, Vol. 77, (10) : 4429-4436

Lindgren, Helena; Honn, Marie; Golovlev, Igor; et al.

MglA and Igl proteins contribute to the modulation of Francisella tularensis live vaccine strain-containing phagosomes in murine macrophages

Infection and Immunity, Vol. 76, (8) : 3502-3510

Bönquist, Linda; Lindgren, Helena; Golovliov, Igor; et al.

The contribution of reactive nitrogen and oxygen species to the killing of Francisella tularensis LVS by murine macrophages.

Microbes and infection, Vol. 7, (3) : 467-475

Lindgren, Helena; Stenman, Linda; Tärnvik, Arne; et al.

A mutant of Francisella tularensis strain SCHU S4 lacking the ability to express a 58-kilodalton protein is attenuated for virulence and is an effective live vaccine

Infection and Immunity, Vol. 73, (12) : 8345-8352

Twine, Susan; Byström, Mona; Chen, Wangxue; et al.

Distinct roles of reactive nitrogen and oxygen species to control infection with the facultative intracellular bacterium Francisella tularensis.

Infection and Immunity, Vol. 72, (12) : 7172-7182

Lindgren, Helena; Stenmark, Stephan; Chen, Wangxue; et al.

Infection with Francisella novicida leads to killing of murine macrophages by necrosis

Lai, Xin-He; Lindgren, Helena; Luan, Shi-Lu; et al.

T-cell-dependent and independent protection against Francisella tularensis

Stenmark, Stephan; Lindgren, Helena; Tärnvik, Arne; et al.

Inhibition of the oxidative burst by Francisella tularensis LVS is dependent on expression of MglA and the pathogenicity island proteins IglB, IglC, and IglD, but is not affected by IFN-γ

Tancred, Linda; Binesse, Johan; Lindgren, Helena; et al.

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Forskningsprojekt

1 januari 2021 till 31 december 2025

Utveckling av ett tularemivaccin