Jonathan Gilthorpe

Kontakt

jonathan.gilthorpe@umu.se

090-786 94 58

Verksam vid

Universitetslektor vid Institutionen för integrativ medicinsk biologi (IMB) Enhet: Grupp Jonathan Gilthorpe

hus H, Johan Bures väg 12, Biologihuset Umeå universitet, 901 87 Umeå

Resistance to chicken amyloid arthropathy is associated with a dysfunctional mutation in serum amyloid A

The FASEB Journal, John Wiley & Sons 2023, Vol. 37, (1)

Falker-Gieske, Clemens; Paul, Nora-Fabienne; Spourita, Maria; et al.

Cerebellum

Marsili, Luca; Davis, Jennie L.; Espay, Alberto J.; et al.

Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming

Journal of Translational Medicine, BioMed Central (BMC) 2023, Vol. 21, (1)

Pateras, Ioannis S.; Williams, Chloe; Gianniou, Despoina D.; et al.

Alteration of Mitochondrial Integrity as Upstream Event in the Pathophysiology of SOD1-ALS

Cells, MDPI 2022, Vol. 11, (7)

Günther, René; Pal, Arun; Williams, Chloe; et al.

ATP-independent molecular chaperone activity generated under reducing conditions

Protein Science, John Wiley & Sons 2022, Vol. 31, (8)

Leppert, Axel; Chen, Gefei; Lianoudaki, Danai; et al.

Serious side effects exceed the risk of hospitalization with COVID-19 in the Swedish population

Román, Sven; Stahel, Anette; Gilthorpe, Jonathan D.; et al.

Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models

iScience, Elsevier 2021, Vol. 24, (12)

Devoy, Anny; Price, Georgia; De Giorgio, Francesca; et al.

Altered perivascular fibroblast activity precedes ALS disease onset

Nature Medicine, Nature Publishing Group 2021, Vol. 27, (4) : 640-646

Månberg, Anna; Skene, Nathan; Sanders, Folkert; et al.

Aggregate-selective antibody attenuates seeded aggregation but not spontaneously evolving disease in SOD1 ALS model mice

Acta neuropathologica communications, BMC 2020, Vol. 8, (1)

Lehmann, Manuela; Marklund, Matthew; Bolender, Anna-Lena; et al.

Role of pannexin-1 in the cellular uptake, release and hydrolysis of anandamide by T84 colon cancer cells

Scientific Reports, Nature Publishing Group 2019, Vol. 9

Alhouayek, Mireille; Sorti, René; Gilthorpe, Jonathan D.; et al.

The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension

Acta Neuropathologica, New York: Springer 2019, Vol. 138, (1) : 85-101

Keskin, Isil; Forsgren, Elin; Lehmann, Manuela; et al.

GLUL Ablation Can Confer Drug Resistance to Cancer Cells via a Malate-Aspartate Shuttle-Mediated Mechanism

Cancers, MDPI 2019, Vol. 11, (12)

Muthu, Magesh; Kumar, Ranjeet; Khaja, Azharuddin Sajid Syed; et al.

Mitochondrial DNA in the tumour microenvironment activates neutrophils and is associated with worse outcomes in patients with advanced epithelial ovarian cancer

British Journal of Cancer, Nature Publishing Group 2019, Vol. 120, (2) : 207-217

Singel, Kelly L.; Grzankowski, Kassondra S.; Khan, A. N. M. Nazmul H.; et al.

Intrathecal treatment trial of rituximab in progressive MS: An open-label phase 1b study

Neurology, Wolters Kluwer 2018, Vol. 91, (20) : E1893-E1901

Bergman, Joakim; Burman, Joachim; Gilthorpe, Jonathan D.; et al.

Cell-type- and region-specific restriction of neurotropic flavivirus infection by viperin

Journal of Neuroinflammation, BioMed Central 2018, Vol. 15

Lindqvist, Richard; Kurhade, Chaitanya; Gilthorpe, Jonathan D.; et al.

Cytokine levels in interstitial brain fluid in progressive multiple sclerosis measured via intracerebral microdialysis

Multiple Sclerosis Journal, SAGE PUBLICATIONS LTD 2016, Vol. 22 : 511-511

Bergman, J.; Dring, Ann; Wuolikainen, Anna; et al.

Neurofilament light in CSF and serum is a sensitive marker for axonal white matter injury in MS

Neurology: Neuroimmunology and neuroinflammation, Vol. 3, (5)

Bergman, Joakim; Dring, Ann; Zetterberg, Henrik; et al.

Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients

PLOS ONE, Vol. 11, (2)

Keskin, Isil; Forsgren, Elin; Lange, Dale J.; et al.

Fast type I interferon response protects astrocytes from flavivirus infection and virus-induced cytopathic effects

Journal of Neuroinflammation, Vol. 13

Lindqvist, Richard; Mundt, Filip; Gilthorpe, Jonathan D.; et al.

Reactivated herpes simplex infection increases the risk of Alzheimer's disease

Alzheimer's & Dementia: Journal of the Alzheimer's Association, Vol. 11, (6) : 593-599

Lövheim, Hugo; Gilthorpe, Jonathan; Adolfsson, Rolf; et al.

Herpes simplex infection and the risk of Alzheimer's disease: a nested case-control study

Alzheimer's & Dementia: Journal of the Alzheimer's Association, Vol. 11, (6) : 587-592

Lövheim, Hugo; Gilthorpe, Jonathan; Johansson, Anders; et al.

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 11, (4) : 879-883

Nordin, Joel Z.; Lee, Yi; Vader, Pieter; et al.

Rapid depletion of B lymphocytes by ultra-low-dose rituximab delivered intrathecally

Neurology: Neuroimmunology and neuroinflammation, Lippincott Williams & Wilkins 2015, Vol. 2, (2)

Svenningsson, Anders; Bergman, Joakim; Dring, Ann; et al.

Extracellular histone H1 is neurotoxic and drives a pro-inflammatory response in microglia.

F1000Research, Vol. 2, (148)

Gilthorpe, Jonathan; Oozeer, Fazal; Nash, Julia; et al.

Intense Inflammation and Nerve Damage in Early Multiple Sclerosis Subsides at Older Age: A Reflection by Cerebrospinal Fluid Biomarkers

PLOS ONE, Vol. 8, (5) : e63172-

Khademi, Mohsen; Dring, Ann M.; Gilthorpe, Jonathan D.; et al.

Fatal neuroinflammation in a case of multiple sclerosis with anti-natalizumab antibodies

Neurology, Vol. 80, (10) : 965-967

Svenningsson, Anders; Dring, Ann Marie; Fogdell-Hahn, Anna; et al.

The roof plate boundary is a bi-directional organiser of dorsal neural tube and choroid plexus development.

Development, Vol. 139, (22) : 4261-4270

Broom, Emma R; Gilthorpe, Jonathan; Butts, Thomas; et al.

Multivariate analysis of inflammatory and neuronal injury markers in cerebrospinal fluid of multiple sclerosis: higher levels are associated with younger age

Journal of Neuroimmunology, Vol. 253, (1-2) : 100-100

Khademi, Mohsen; Dring, Ann; Gilthorpe, Jonathan; et al.

MRP14 (S100A9) protein interacts with alzheimer beta-amyloid peptide and induces its fibrillization

PLOS ONE, San Francisco: Public Library of Science 2012, Vol. 7, (3) : e32953-

Zhang, Ce; Liu, Yonggang; Gilthorpe, Jonathan; et al.

Lrrn1 is required for formation of the midbrain-hindbrain boundary and organiser through regulation of affinity differences between midbrain and hindbrain cells in chick

Developmental Biology, Elsevier 2011, Vol. 352, (2) : 341-352

Tossell, Kyoko; Andreae, Laura C; Cudmore, Chloe; et al.

Analysis of Lrrn1 expression and its relationship to neuromeric boundaries during chick neural development

Neural Development, Vol. 2, (22) : 1-16

Andreae, Laura C; Peukert, Daniela; Lumsden, Andrew; et al.

Characterization of zebrafish PSD-95 gene family members.

Journal of Neurobiology, Vol. 63, (2) : 91-105

Meyer, Martin P; Trimmer, James S; Gilthorpe, Jonathan; et al.

Induction of a parafacial rhythm generator by rhombomere 3 in the chick embryo.

Journal of Neuroscience, Vol. 24, (42) : 9383-9390

Coutinho, Ana P; Borday, Caroline; Gilthorpe, Jonathan; et al.

Multiple levels of transcriptional and post-transcriptional regulation are required to define the domain of Hoxb4 expression

Development, Vol. 130, (12) : 2717-2728

Brend, Tim; Gilthorpe, Jonathan; Summerbell, Dennis; et al.

The migration of cerebellar rhombic lip derivatives.

Development, Vol. 129, (20) : 4719-4728

Gilthorpe, Jonathan; Papantoniou, Elli-Kalliopi; Chédotal, Alain; et al.

Spatially specific expression of Hoxb4 is dependent on the ubiquitous transcription factor NFY.

Development, Vol. 129, (16) : 3887-99

Gilthorpe, Jonathan; Vandromme, Marie; Brend, Tim; et al.

No evidence for ventrally migrating neural tube cells from the mid- and hindbrain.

Developmental Dynamics, Vol. 223, (1) : 163-7

Yaneza, May; Gilthorpe, Jonathan; Lumsden, Andrew; et al.

Neurobiology.

Current Opinion in Neurobiology, Vol. 11, (3) : 259-66

Lumsden, A; Andreae, L; Gilthorpe, Jonathan; et al.

Reporter genes for the study of transcriptional regulation in transgenic mouse embryos.

Methods in Molecular Biology, Vol. 97 : 159-182

Gilthorpe, Jonathan; Rigby, P W

Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes.

Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, (5) : 1684-1688

Aparicio, S; Morrison, A; Gould, A; et al.

Multiple positive and negative regulatory elements in the promoter of the mouse homeobox gene Hoxb-4.

Molecular and Cellular Biology, American Society for Microbiology 1994, Vol. 14, (12) : 8143-8154

Gutman, Alejandro; Gilthorpe, Jonathan; Rigby, PETER W. J.

Reshaping the role of METTL3 in breast tumorigenesis

Achour, Cyrinne; Bhattarai, Devi Prasad; Esteva-Socias, Margalida; et al.

Enhanced protein misfolding in patient-derived models of amyotrophic lateral sclerosis

Forsgren, Elin; Lehmann, Manuela; Weygandt Mathis, Mackenzie; et al.

A Novel mutation D96Mfs*8 in SOD1 identified in a Swedish ALS patient results in a truncated and heavily aggregation-prone protein

Forsgren, Elin; Nordin, Frida; Nordström, Ulrika; et al.

Low oxygen tension induces misfolding and aggregation of superoxide dismutase in ALS patient-derived motor neurons

Keskin, Isil; Forsgren, Elin; Andersen, Peter M.; et al.

Viperin restrict neurotropic flavivirus infection in cell type and region-specific manner

Lindqvist, Richard; Kurhade, Chaitanya; Gilthorpe, Jonathan; et al.

The catalytic-independent function of LSD1 modulates the epigenetic landscape of mouse embryonic stem cells

Malla, Sandhya; Kumari, Kanchan; Martinez Gamero, Carlos; et al.

The exosome membrane localization of histones is independent of DNA and upregulated in response to stress

Muthukrishnan, Uma; Natarajan, Balasubramanian; Mäger, Imre; et al.

TAT-5 and TAT-6 P4-family ATPases regulate the release of extracellular vesicles containing polycystins from Caenorhabditis elegans sensilla

Nilsson, Lars; Rahmani, Shapour; Hubert, Madlen; et al.

Mitochondrial DNA in the tumor microenvironment activates neutrophils and is associated with worsened outcomes in patients with advanced epithelial ovarian cancer

Singel, Kelly L.; Grzankowski, Kassondra S.; Khan, ANM Nazmul H.; et al.

Visa publikationer i DiVA

Forskargrupper

Forskningsledare

ALS-forskning i Umeå

Publicerad: 28 okt, 2019

Vetenskapsmiljoner till medicinsk forskning i Umeå