Leif Carlsson

Vetenskaplig meritering: Docent

Kontakt

leif.carlsson@umu.se

090-786 64 30

Verksam som

Professor emeritus vid Institutionen för medicinsk och translationell biologi Enhet: Avdelningen för molekylär medicin

hus H, Johan Bures väg 12, Biologihuset Umeå universitet, 901 87 Umeå

Reduced mTORC1-signaling in progenitor cells leads to retinal lamination deficits

Developmental Dynamics, John Wiley & Sons 2024, Vol. 253, (10) : 922-939

Nord, Christoffer; Jones, Iwan; Garcia-Maestre, Maria; et al.

Reduced mTORC1-signaling in retinal ganglion cells leads to vascular retinopathy

Developmental Dynamics, John Wiley & Sons 2022, Vol. 251, (2) : 321-335

Jones, Iwan; Hägglund, Anna-Carin; Carlsson, Leif

Helios represses megakaryocyte priming in hematopoietic stem and progenitor cells

Journal of Experimental Medicine, Rockefeller University Press 2021, Vol. 218, (10)

Cova, Giovanni; Taroni, Chiara; Deau, Marie-Céline; et al.

A robust approach for the generation of functional hematopoietic progenitor cell lines to model leukemic transformation

Blood Advances, American Society of Hematology 2021, Vol. 5, (1) : 39-53

Doma, Eszter; Mayer, Isabella Maria; Brandstoetter, Tania; et al.

Human Embryonic Stem Cell-derived Neural Crest Cells Promote Sprouting and Motor Recovery Following Spinal Cord Injury in Adult Rats

Cell Transplantation, Sage Publications 2021, Vol. 30

Jones, Iwan; Novikova, Liudmila N.; Wiberg, Mikael; et al.

Local retinoic acid signaling directs emergence of the extraocular muscle functional unit

PLoS biology, Public Library Science 2020, Vol. 18, (11)

Comai, Glenda Evangelina; Tesarova, Marketa; Dupe, Valerie; et al.

Reduced mTORC1-signalling in retinal progenitor cells leads to visual pathway dysfunction

Biology Open, The Company of Biologists 2019, Vol. 8, (8)

Jones, Iwan; Hägglund, Anna-Carin; Carlsson, Leif

Regenerative effects of human embryonic stem cell-derived neural crest cells for treatment of peripheral nerve injury

Journal of Tissue Engineering and Regenerative Medicine, Vol. 12, (4) : E2099-E2109

Jones, Iwan; Novikova, Liudmila N.; Novikov, Lev N.; et al.

Development and validation of an in vitro model system to study peripheral sensory neuron development and injury

Scientific Reports, Nature Publishing Group 2018, Vol. 8

Jones, Iwan; Yelhekar, Tushar D.; Wiberg, Rebecca; et al.

A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development

Disease Models and Mechanisms, Vol. 10, (3) : 245-257

Hagglund, Anna-Carin; Jones, Iwan; Carlsson, Leif

A low-carbohydrate high-fat diet decreases lean mass and impairs cardiac function in pair-fed female C57BL/6J mice

Nutrition & Metabolism, BioMed Central (BMC) 2016, Vol. 13

Nilsson, Jessica; Ericsson, Madelene; Joibari, Masoumeh Motamedi; et al.

A novel mouse model of tuberous sclerosis complex (TSC): eye-specific Tsc1-ablation disrupts visual-pathway development

Disease Models and Mechanisms, Vol. 8, (12) : 1517-1529

Jones, Iwan; Hägglund, Anna-Carin; Törnqvist, Gunilla; et al.

Canonical Wnt/beta-Catenin Signalling Is Essential for Optic Cup Formation

PLOS ONE, Public Library of Science 2013, Vol. 8, (12) : e81158-

Hägglund, Anna-Carin; Berghard, Anna; Carlsson, Leif

Lhx2-dependent specification of olfactory sensory neurons is required for successful integration of olfactory, vomeronasal, and GnRH neurons

The FASEB Journal, Federation of American Society of Experimental Biology (FASEB) 2012, Vol. 26, (8) : 3464-3472

Berghard, Anna; Hägglund, Anna-Carin; Bohm, Staffan; et al.

The Lhx2 transcription factor controls Thalamocortical Axonal guidance by specific regulation of Robo1 and Robo2 receptors

Journal of Neuroscience, Washington, DC, USA: Social Neuroscience 2012, Vol. 32, (13) : 4372-4385

Marcos-Mondejar, Paula; Peregrin, Sandra; Li, James Y.; et al.

Lhx2 is required for patterning and expansion of a distinct progenitor cell population committed to eye development

PLOS ONE, San Francisco, CA: Public Library of Science 2011, Vol. 6, (8) : e23387-

Hägglund, Anna-Carin; Dahl, Lina; Carlsson, Leif

Periodiskt uttryck av genen Lhx2 reglerar hårväxten

Läkartidningen, Vol. 107, (24-25) : 1616-1616

Carlsson, Leif

Cyclic expression of lhx2 regulates hair formation.

PLoS genetics, Vol. 6, (4) : e1000904-

Törnqvist, Gunilla; Sandberg, Anna; Hägglund, Anna-Carin; et al.

Lhx2 promotes self-renewal of a distinct multipotent hematopoietic progenitor cell in embryoid bodies

PLoS one, Vol. 3, (4) : e2025-

Dahl, Lina; Richter, Karin; Carlsson, Leif

Haematopoietic progenitor cells utilise conventional PKC to suppress PKB/Akt activity in response to c-Kit stimulation

British Journal of Haematology, Oxford: Blackwell Scientific 2007, Vol. 136, (2) : 260-268

Edling, Charlotte E.; Pedersen, Malin; Carlsson, Leif; et al.

Identification of an N-terminal transactivation domain of Runx1 that separates molecular function from global differentiation function.

J Biol Chem, Vol. 281, (35) : 25659-69

Liu, Hebin; Carlsson, Leif; Grundström, Thomas

Global gene expression analyses of hematopoietic stem cell-like cell lines with inducible Lhx2 expression

BMC Genomics, Vol. 7 : 75-

Richter, Karin; Wirta, Valtteri; Dahl, Lina; et al.

A road map toward defining the role of Smad signaling in hematopoietic stem cells.

Stem Cells, Vol. 24, (4) : 1128-36

Utsugisawa, Taiju; Moody, Jennifer L; Aspling, Marie; et al.

Catalog of gene expression in adult neural stem cells and their in vivo microenvironment

Experimental Cell Research, San Diego: Elsevier 2006, Vol. 312, (10) : 1798-1812

Williams, Cecilia; Wirta, Valtteri; Meletis, Konstantinos; et al.

The Lim homeobox gene Lhx2 is required for olfactory sensory neuron identity

Development, Vol. 131, (21) : 5319-5326

Kolterud, Åsa; Alenius, Mattias; Carlsson, Leif; et al.

Lhx2 is expressed in the septum transversum mesenchyme that becomes an integral part of the liver and the formation of these cells is independent of functional Lhx2

Gene Expression Patterns, Elsevier 2004, Vol. 4, (5) : 521-528

Kolterud, Åsa; Wandzioch, Ewa; Carlsson, Leif

Activation of the MAP kinase pathway by c-Kit is PI-3 kinase dependent in hematopoietic progenitor/stem cell lines

Blood, Vol. 104, (1) : 51-57

Wandzioch, Ewa; Edling, Charlotte E; Palmer, Ruth H; et al.

Lhx2-/- mice develop liver fibrosis

Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences 2004, Vol. 101, (47) : 16549-16554

Wandzioch, Ewa; Kolterud, Åsa; Jacobsson, Maria; et al.

Multipotent hematopoietic progenitor cells immortalized by Lhx2 self-renew by a cell nonautonomous mechanism

Experimental Hematology, Elsevier 2001, Vol. 29, (8) : 1019-1028

Pinto do O, Perpetua; Wandzioch, Ewa; Kolterud, Åsa; et al.

Expression of the LIM-homeobox gene LH2 generates immortalized Steel factor-dependent multipotent hematopoietic precursors

EMBO Journal, Oxford University Press 1998, Vol. 17, (19) : 5744-5756

Pinto do Ó, Perpétua; Kolterud, Åsa; Carlsson, Leif

Lhx2 is required for expansion of progenitor cells committed to eye development

Hägglund, AC; Dahl, Lina; Carlsson, Leif

Visa publikationer i DiVA

Forskargrupper

Forskningsledare

Leif Carlsson