MIMS Investigators

Lars-Anders Carlson

I am fascinated by how viruses rearrange the interior of the cells they infect. A positive-strand RNA virus will often have a genome with one single gene and around ten thousand bases, and yet it can completely remodel the cytoplasm within hours of infection. To understand how this happens, we are combining methods such as biochemical reconstitution and in situ structural biology (cryo-electron tomography).  

Laura Carroll

(Meta)genomic sequencing is playing an increasingly pivotal role in clinical and public health microbiology. As such, the amount of publicly available (meta)genomic data derived from microbes, including pathogens, is growing rapidly. As a computational microbiologist, I develop and utilize bioinformatic approaches, which can query these massive data sets to improve pathogen surveillance, source tracking, outbreak detection, and risk evaluation efforts.