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Anders Hofer

Associate Professor and docent in Medical Biochemistry

 

Research qualifications: Docent
Educational qualifications: Recognised university teacher

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Affiliation
Associate professor at Department of Medical Biochemistry and Biophysics Role: Director of studies
Location
KB.H6, Campus, Umeå, A6.50.15 Umeå universitet, 901 87 Umeå

I am researching nucleotide metabolism – enzymes, regulation and drug development.

Nucleotides have central roles in cellular metabolism by being energy donors and building blocks in DNA and RNA. In my research group, we are studying the regulation of some of the enzymes involved in the nucleotide metabolism with the focus on ribonucleotide reductase and nucleoside kinases.

This research includes the study of nucleotide metabolism in several pathogens where we try to exploit differences in nucleotide metabolism compared to mammalian cells in order to selectively kill the pathogens with minimized side effects.

Nucleic Acids Research, Oxford University Press 2024, Vol. 52, (1)
Purhonen, Janne; Hofer, Anders; Kallijärvi, Jukka
Mitochondrion (Amsterdam. Print), Elsevier 2023, Vol. 71 : 93-103
Debar, Louis; Ishak, Layal; Moretton, Amandine; et al.
FEMS Microbiology Reviews, Oxford University Press 2023, Vol. 47, (3)
Hofer, Anders
Pathogens, MDPI 2022, Vol. 11, (12)
Ebenwaldner, Carmen; Hornyak, Peter; García-Saura, Antonio Ginés; et al.
Biochemistry, American Chemical Society (ACS) 2022, Vol. 61, (15) : 1633-1641
Fietze, Tobias; Wilk, Piotr; Kabinger, Florian; et al.
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2022, Vol. 298, (6)
Krakovka, Sascha; Ranjbarian, Farahnaz; Luján, Lucas A.; et al.
Inorganic Chemistry, American Chemical Society (ACS) 2022, Vol. 61, (34) : 13561-13575
Marchetti, Fabio; Tombesi, Alessia; Di Nicola, Corrado; et al.
Nucleic Acids Research, Oxford University Press 2022, Vol. 50, (3)
Ranjbarian, Farahnaz; Sharma, Sushma; Falappa, Giulia; et al.
Biochemistry, Vol. 61, (2) : 92-106
Rehling, Daniel; Scaletti, Emma Rose; Rozman Grinberg, Inna; et al.
Antibiotics, MDPI 2021, Vol. 10, (11)
Baldassarri, Cecilia; Falappa, Giulia; Mazzara, Eugenia; et al.
Molecules, MDPI 2020, Vol. 25, (14)
Frezza, Claudio; Venditti, Alessandro; Bianco, Armandodoriano; et al.
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2020, Vol. 295, (46) : 15576-15587
Martinez-Carranza, Markel; Jonna, Venkateswara Rao; Lundin, Daniel; et al.
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2020, Vol. 295, (33) : 11891-11901
Nemeth, Brigitta; Land, Henrik; Magnuson, Ann; et al.
Nucleic Acids Research, Oxford University Press 2020, Vol. 48, (1) : 264-277
Schmidt, Tobias T; Sharma, Sushma; Reyes, Gloria X; et al.
Nature Communications, Nature Publishing Group 2019, Vol. 10
Hulpia, Fabian; Mabille, Dorien; Campagnaro, Gustavo D.; et al.
Environmental Science and Pollution Research, Vol. 25, (11) : 10184-10206
Benelli, Giovanni; Maggi, Filippo; Pavela, Roman; et al.
Protein Science, Wiley-Blackwell 2018, Vol. 27 : 87-88
Grinberg, Inna; McGann, Matthew; Lundin, Daniel; et al.
Journal of Molecular Biology, Elsevier 2018, Vol. 430, (18, Part B) : 3157-3169
Gupta, Arun A.; Reinartz, Ines; Karunanithy, Gogulan; et al.
Ecotoxicology and Environmental Safety, Elsevier 2018, Vol. 156 : 154-165
Kamte, Stephane L. Ngahang; Ranjbarian, Farahnaz; Cianfaglione, Kevin; et al.
eLIFE, ELIFE SCIENCES PUBLICATIONS LTD 2018, Vol. 7
Rozman Grinberg, Inna; Lundin, Daniel; Hasan, Mahmudul; et al.
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2018, Vol. 293, (41) : 15889-15900
Rozman Grinberg, Inna; Lundin, Daniel; Sahlin, Margareta; et al.
Molecular Microbiology, John Wiley & Sons 2018, Vol. 109, (3) : 291-305
Schmitt, Andreas; Jiang, Kai; Camacho, Martha I.; et al.
Fitoterapia (Milano), Elsevier 2018, Vol. 124 : 145-151
Sut, Stefania; Dall'Acqua, Stefano; Baldan, Valeria; et al.
Cell Host and Microbe, CELL PRESS 2017, Vol. 21, (3) : 376-389
Bugaytsova, Jeanna A.; Björnham, Oscar; Chernov, Yevgen A.; et al.
Biophysical Journal, CELL PRESS 2017, Vol. 112, (3) : 33A-33A
Gupta, Arun; Reinartz, Ines; Spilotros, Alessandro; et al.
International Journal of Environmental Research and Public Health, MDPI AG 2017, Vol. 14, (7)
Kamte, Stephane L. Ngahang; Ranjbarian, Farahnaz; Campagnaro, Gustavo Daniel; et al.
Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 2017, Vol. 292, (46) : 19044-19054
Loderer, Christoph; Jonna, Venkateswara Rao; Crona, Mikael; et al.
Parasitology international, Vol. 66, (2) : 146-151
Petrelli, Riccardo; Ranjbarian, Farahnaz; Dall'Acqua, Stefano; et al.
Antimicrobial Agents and Chemotherapy, American Society for Microbiology 2017, Vol. 61, (6)
Ranjbarian, Farahnaz; Vodnala, Munender; Alzahrani, Khalid J. H.; et al.
Scientific Reports, Nature Publishing Group 2016, Vol. 6
Chiruvella, Kishore K; Rajaei, Naghmeh; Jonna, Venkateswara Rao; et al.
Molecular Oncology, Vol. 10, (9) : 1375-1386
Crona, Mikael; Codo, Paula; Jonna, Venkateswara Rao; et al.
Structure, Vol. 24, (6) : 906-917
Johansson, Renzo; Jonna, Venkateswara Rao; Kumar, Rohit; et al.
Molecules, Vol. 21, (8)
Petrelli, Riccardo; Orsomando, Giuseppe; Sorci, Leonardo; et al.
Virus Research, Elsevier 2016, Vol. 223 : 20-27
Sadanandan, Sajna Anand; Ekström, Jens-Ola; Jonna, Venkateswara Rao; et al.
Journal of Biological Chemistry, Vol. 291, (22) : 11717-11726
Vodnala, Munender; Ranjbarian, Farahnaz; Pavlova, Anna; et al.
PLOS ONE, Vol. 10, (7)
Crona, Mikael; Hofer, Anders; Astorga-Wells, Juan; et al.
Journal of Biological Chemistry, Vol. 290, (28) : 17339-17348
Jonna, Venkateswara Rao; Crona, Mikael; Rofougaran, Reza; et al.
Bioorganic & Medicinal Chemistry Letters, Vol. 24, (22) : 5304-5309
Petrelli, Riccardo; Meli, Maria; Vita, Patrizia; et al.
Journal of Biological Chemistry, Vol. 289, (19) : 13054-13065
Vande Voorde, Johan; Sabuncuoglu, Suna; Noppen, Sam; et al.
Protein Engineering Design & Selection, Oxford University Press 2013, Vol. 26, (7) : 445-452
Falahati, Hanieh; Pazhang, Mohammad; Zareian, Shekufeh; et al.
Phytochemistry, Vol. 79 : 39-45
Decker, Daniel; Meng, Meng; Gornicka, Agnieszka; et al.
Critical reviews in biochemistry and molecular biology, London: Informa Healthcare 2012, Vol. 47, (1) : 50-63
Hofer, Anders; Crona, Mikael; Logan, Derek T; et al.
Journal of Biological Chemistry, Vol. 287, (21) : 17628-17636
Ranjbarian, Farahnaz; Vodnala, Munender; Vodnala, Sharvani Munender; et al.
Nucleic Acids Research, Oxford Journals 2011, Vol. 39, (4) : 1381-9
Crona, Mikael; Moffatt, Connor; Friedrich, Nancy C; et al.
Journal of Biological Chemistry, Bethesda, Md.: American Society for Biochemistry and Molecular Biology 2011, Vol. 286, (38) : 33053-33060
Crona, Mikael; Torrents, Eduard; Rohr, Asmund K.; et al.
Nucleosides, Nucleotides & Nucleic Acids, Vol. 29, (4-6) : 433-437
Björnberg, O; Vodnala, Munender; Domkin, Vladimir; et al.
Structure, Vol. 17, (11) : 1442-1452
Elmlund, Hans; Baraznenok, Vera; Linder, Tomas; et al.
Journal of Molecular Biology, Vol. 380, (4) : 656-66
Andersen, Gorm; Björnberg, Olof; Polakova, Silvia; et al.
Nucleic Acids Research, Vol. 36, (2) : 393-403
Farge, Géraldine; Holmlund, Teresa; Khvorostova, Julia; et al.
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2008, Vol. 283, (51) : 35310-35318
Rofougaran, Reza; Crona, Mikael; Vodnala, Munender; et al.

Research groups

Head of research
Anders Hofer

Research projects

I am teaching in semester 1-3 of the Medical Programme and in the first semester of the Dentistry Programme. I am also responsible for the first semester of the Medical Programme and a member of the programme board (PRL).