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Mikael Elofsson

Dean Faculty of Science and Technology

Research qualifications: Docent

Contact

Works at

Affiliation
Location
KB.C4, Linnaeus väg 10, C4.25.07 Umeå universitet, 901 87 Umeå
Affiliation
Affiliated as professor at Faculty Office of Science and Technology
Location
Förvaltningshuset, plan 6, Universitetstorget 16 Umeå universitet, 901 87 Umeå

In 1996 Mikael Elofsson obtained his Ph.D. in organic chemistry at the Lund Institute of Technology, Lund, Sweden. In the group of Professor Jan Kihlberg he worked with synthesis of glycosylated amino acids and solid-phase glycopeptide synthesis. Thereafter he spent three years as postdoc in the lab of Professor Craig M. Crews at Yale University, CT, USA working primarily on epoxyketone proteasome inhibitors. The work eventually led to the drug Kyprolis (Carfilzomib) that was approved by the US Food and Drug Administration in  2012 and by the European Medicines Agency in 2015.

In 1999 he was recruited to Umeå University and in 2008 he was appointed Professor. Since 2017 he is the Dean of the Faculty of Science and Technology. His lab focuses on chemical approaches to investigate how bacteria and viruses cause infection and identification of antibacterial and antiviral compounds, for example natural products, glycoconjugates and small molecules. Starting points are typically generated by screening-based technologies followed by iterative design, synthesis and evaluation in biochemical, biophysical systems and infection models in vitro and in vivo.

Mikael Elofsson on Linkedin
Mikael Elofsson on Google Scholar

 

 

 

RSC Advances, Royal Society of Chemistry 2022, Vol. 12, (4) : 2319-2331
Johansson, Emil; Caraballo, Remi; Zocher, Georg; et al.
Applied Sciences, MDPI 2021, Vol. 11, (7)
El-Schich, Zahra; Zhang, Yuecheng; Göransson, Tommy; et al.
Journal of Organic Chemistry, American Chemical Society (ACS) 2021, Vol. 86, (13) : 9145-9154
Johansson, Emil; Caraballo, Remi; Elofsson, Mikael
International Journal of Molecular Sciences, MDPI 2021, Vol. 22, (16)
Johansson, Emil; Caraballo, Remi; Hurdiss, Daniel L.; et al.
Biomolecules, MDPI 2021, Vol. 11, (1)
Sundin, Charlotta; Saleeb, Michael; Spjut, Sara; et al.
Viruses, MDPI 2020, Vol. 12, (3)
Gwon, Yong-Dae; Strand, Mårten; Lindquist, Richard; et al.
ACS Chemical Biology, American Chemical Society (ACS) 2020, Vol. 15, (10) : 2683-2691
Johansson, Emil; Caraballo, Remi; Mistry, Nitesh; et al.
Virulence, Taylor & Francis 2020, Vol. 11, (1) : 795-804
Sharma, Prerana; Elofsson, Mikael; Roy, Sanhita
Scientific Reports, Nature Publishing Group 2020, Vol. 10, (1)
Sundin, Charlotta; Zetterström, Caroline E.; Vo, Duy Duc; et al.
Cell Death and Differentiation, Nature Publishing Group 2019, Vol. 26, (9) : 1615-1630
Beck, Carole; Rodriguez-Vargas, José Manuel; Boehler, Christian; et al.
Viruses, MDPI 2019, Vol. 11, (5)
Chandra, Naresh; Frängsmyr, Lars; Imhof, Sophie; et al.
Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2019, Vol. 9
Massai, Francesco; Saleeb, Michael; Doruk, Tugrul; et al.
Molecular plant pathology, John Wiley & Sons 2019, Vol. 20, (1) : 20-32
Puigvert, Marina; Sole, Montserrat; Lopez-Garcia, Belen; et al.
Biochemical and Biophysical Research Communications - BBRC, Elsevier 2019, Vol. 511, (1) : 117-121
Tükenmez, Hasan; Edström, Isabel; Kalsum, Sadaf; et al.
SLAS DISCOVERY, Sage Publications 2018, Vol. 23, (4) : 353-362
Ekblad, Torun; Verheugd, Patricia; Lindgren, Anders E.; et al.
Scientific Reports, NATURE PUBLISHING GROUP 2018, Vol. 8
Islam, Md. Koushikul; Strand, Mårten; Saleeb, Michael; et al.
Nature Communications, Nature Publishing Group 2018, Vol. 9
Karlberg, Tobias; Hornyak, Peter; Pinto, Ana Filipa; et al.
Organic Letters, American Chemical Society (ACS) 2018, Vol. 20, (21) : 6650-6654
Krzyzanowski, Adrian; Saleeb, Michael; Elofsson, Mikael
ChemistryOpen, Wiley-VCH Verlagsgesellschaft 2018, Vol. 7, (12) : 953-956
Kumar, Arvind; Saleeb, Michael; Werz, Dominik; et al.
Frontiers in Microbiology, Frontiers Media S.A. 2018, Vol. 9
Mojica, Sergio; Eriksson, Anna U.; Davis, Rohan A.; et al.
European Journal of Medicinal Chemistry, Elsevier 2018, Vol. 143 : 1077-1089
Saleeb, Michael; Mojica, Sergio; Eriksson, Anna U.; et al.
European Journal of Medicinal Chemistry, Elsevier 2018, Vol. 143 : 568-576
Saleeb, Michael; Sundin, Charlotta; Aglar, Öznur; et al.
SLAS Discovery, Sage Publications 2018, Vol. 23, (8) : 815-822
Zetterström, Caroline E.; Uusitalo, Pia; Qian, Weixing; et al.
Antimicrobial Agents and Chemotherapy, American society for microbiology 2017, Vol. 61, (10)
Mojica, Sergio A.; Salin, Olli; Bastidas, Robert J.; et al.
ACS Combinatorial Science, American Chemical Society (ACS) 2017, Vol. 19, (6) : 370-376
Qin, Liena; Vo, Duc-Duy; Nakhai, Azadeh; et al.
Journal of enzyme inhibition and medicinal chemistry (Print), Vol. 32, (1) : 513-521
Sunduru, Naresh; Svensson, Mona; Cipriano, Mariateresa; et al.
Journal of antibiotics (Tokyo. 1968), Japan Antibiotics Research Association 2017, Vol. 70, (9) : 937-943
Uusitalo, Pia; Hägglund, Ulrik; Rhöös, Elin; et al.
Frontiers in Microbiology, Vol. 7
Huerta-Uribe, Alejandro; Marjenberg, Zoe R.; Yamaguchi, Nao; et al.
European Journal of Organic Chemistry, (3) : 426-429
Lindgren, Anders E. G.; Oberg, Christopher T.; Hillgren, J. Mikael; et al.
Journal of Biomolecular Screening, Vol. 21, (6) : 590-595
Pinto, Ana Filipa; Ebrahimi, Mahsa; Saleeb, Michael; et al.
Advanced Synthesis and Catalysis, Wiley-VCH Verlagsgesellschaft 2016, Vol. 358, (24) : 4085-4092
Vo, Duc Duy; Elofsson, Mikael
European Journal of Medicinal Chemistry, Elsevier 2015, Vol. 103 : 191-209
Caraballo, Remi; Larsson, Mikael; Nilsson, Stefan K.; et al.
Organic and biomolecular chemistry, Vol. 13, (35) : 9194-9205
Caraballo, Rémi; Saleeb, Michael; Bauer, Johannes; et al.
European Journal of Medicinal Chemistry, Vol. 95 : 546-551
Ekblad, Torun; Lindgren, Anders E. G.; Andersson, C. David; et al.
Journal of antibiotics (Tokyo. 1968), Vol. 68, (10) : 609-614
Hakala, Elina F.; Hanski, Leena; Uvell, Hanna; et al.
Journal of Biomolecular Screening, Vol. 20, (2) : 285-91
Stylianou, Marios; Uvell, Hanna; Lopes, Jose Pedro; et al.
European Journal of Medicinal Chemistry, Vol. 101 : 595-603
Sunduru, Naresh; Salin, Olli; Gylfe, Åsa; et al.
Journal of Bacteriology, American Society for Microbiology 2014, Vol. 196, (16) : 2989-3001
Bao, Xiaofeng; Gylfe, Åsa; Sturdevant, Gail L.; et al.
Journal of natural products (Print), Washington: American Chemical Society (ACS) 2014, Vol. 77, (12) : 2633-2640
Davis, Rohan A.; Beattie, Karren D.; Xu, Min; et al.
ChemMedChem, Vol. 9, (10) : 2309-2326
Horvath, Dragos; Lisurek, Michael; Rupp, Bernd; et al.
Biochemical and Biophysical Research Communications - BBRC, Elsevier 2014, Vol. 450, (2) : 1063-1069
Larsson, Mikael; Caraballo, Rémi; Ericsson, Madelene; et al.
Methods in Molecular Biology, Springer 2014, Vol. 1056 : 169-188
Lindgren, Anders E G; Larsson, Andreas; Linusson, Anna; et al.
Antimicrobial Agents and Chemotherapy, American Society for Microbiology 2014, Vol. 58, (5) : 2968-2971
Marwaha, Sania; Uvell, Hanna; Salin, Olli; et al.
Journal of Inorganic Biochemistry, Elsevier 2014, Vol. 138 : 1-8
Rzhepishevska, Olena; Hakobyan, Shoghik; Ekstrand-Hammarström, Barbro; et al.
Marine Drugs, MDPI 2014, Vol. 12, (2) : 799-821
Strand, Mårten; Carlsson, Marcus; Uvell, Hanna; et al.
Antimicrobial Agents and Chemotherapy, Vol. 58, (7) : 4123-4130
Sun, Kun; Bröms, Jeanette; Lavander, Moa; et al.

Research groups

Head of research
Mikael Elofsson lab

Research projects

1 January 2017 until 31 December 2017