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Umeå universitet
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Huvudmenyn dold.
Personalbild Benny Björkblom

Benny Björkblom

Scientist at the Department of Chemistry

Kontakt

E-post
benny.bjorkblom@umu.se
Telefon
090-786 62 30

Verksam som

Anknytning
Staff scientist vid Kemiska institutionen
Plats
KB.B4, Linnaeus väg 10 Umeå universitet, 901 87 Umeå

My research focuses on mass spectrometry-based clinical metabolomics with a particular interest in understanding metabolic processes linked to early brain tumor development, metabolic phenotyping of tumor subtypes and metabolic markers for tumor progression and treatment. Our work is enabled through fruitful collaborations with clinical researchers nationally and internationally.

Characterizing long- and short-survival glioblastoma patients with FLT-PET/MRI and metabolomics
Neuro-Oncology Advances, Oxford University Press 2025, Vol. 7, (1)
Axelsson, Jan; Björkblom, Benny; Asklund, Thomas; et al.
OPLS-based multiclass classification and data-driven interclass relationship discovery
Journal of Chemical Information and Modeling, American Chemical Society (ACS) 2025, Vol. 65, (4) : 1762-1770
Forsgren, Edvin; Björkblom, Benny; Trygg, Johan; et al.
Antidepressants and survival in glioma: a registry-based retrospective cohort study
Neuro-Oncology Practice, Oxford University Press 2024, Vol. 11, (2) : 125-131
Edström, Sonja; Numan Hellquist, Barbro; Sandström, Maria; et al.
Blood based metabolic markers of glioma from pre-diagnosis to surgery
Scientific Reports, Springer Nature 2024, Vol. 14
Löding, Sebastian; Antti, Henrik; Sjöberg, Rickard L.; et al.
Antidepressant drugs and risk of developing glioma: a national registry-based case control study and a meta-analysis
American Journal of Epidemiology, Oxford University Press 2024, Vol. 193, (11) : 1592-1599
Malmberg, Charlotte; Numan Hellquist, Barbro; Sadanandan, Sajna Anand; et al.
Sertraline/chloroquine combination therapy to target hypoxic and immunosuppressive serine/glycine synthesis-dependent glioblastomas
Oncogenesis, Springer Nature 2024, Vol. 13, (1)
Sánchez-Castillo, Anaís; Savelkouls, Kim G.; Baldini, Alessandra; et al.
LAPTM4B counteracts ferroptosis via suppressing the ubiquitin-proteasome degradation of SLC7A11 in non-small cell lung cancer
Cell Death and Disease, Springer Nature 2024, Vol. 15, (6)
Yan, Ruyu; Liu, Dan; Guo, Hongjuan; et al.
Altered plasma metabolite levels can be detected years before a glioma diagnosis
JCI Insight, American Society For Clinical Investigation 2023, Vol. 8, (19)
Löding, Sebastian; Andersson, Ulrika; Kaaks, Rudolf; et al.
Low-grade glioma risk SNP rs11706832 is associated with type I interferon response pathway genes in cell lines
Scientific Reports, Springer Nature 2023, Vol. 13
Rosenbaum, Adam; Dahlin, Anna M.; Andersson, Ulrika; et al.
Distinct metabolic hallmarks of WHO classified adult glioma subtypes
Neuro-Oncology, Oxford University Press 2022, Vol. 24, (9) : 1454-1468
Björkblom, Benny; Wibom, Carl; Eriksson, Maria; et al.
Robusta biomarkörer för prediktion av risk och sjukdom: en utvärdering av reproducerbarheten hos de stora kommersiella omik-plattformarna
Umeå universitet 2022
Rentoft, Matilda; Melin, Beatrice S.; Wibom, Carl; et al.
Prediagnostic biomarkers for early detection of glioma: using case-control studies from cohorts as study approach
Neuro-Oncology Advances, Oxford University Press 2022, Vol. 4 : II73-II80
Wu, Wendy Yi-Ying; Dahlin, Anna M.; Wibom, Carl; et al.
Pre-diagnostic levels of sVEGFR2, sTNFR2, sIL-2Rα and sIL-6R are associated with glioma risk: A nested case–control study of repeated samples
Cancer Medicine, John Wiley & Sons 2022, Vol. 11, (4) : 1016-1025
Wu, Wendy Yi-Ying; Späth, Florentin; Wibom, Carl; et al.
Metabolic response patterns in brain microdialysis fluids and serum during interstitial cisplatin treatment of high-grade glioma
British Journal of Cancer, Nature Publishing Group 2020, Vol. 122, (2) : 221-232
Björkblom, Benny; Jonsson, Pär; Tabatabaei, Pedram; et al.
Identification of Pre-Diagnostic Metabolic Patterns for Glioma Using Subset Analysis of Matched Repeated Time Points
Cancers, MDPI 2020, Vol. 12, (11)
Jonsson, Pär; Antti, Henrik; Späth, Florentin; et al.
Pre-diagnostic plasma metabolites linked to future brain tumor development
Neuro-Oncology, Oxford University Press 2018, Vol. 20 : 288-289
Björkblom, Benny; Jonsson, Pär; Späth, Florentin; et al.
DJ-1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis
Human Molecular Genetics, Oxford University Press 2017, Vol. 26, (20) : 4028-4041
Piston, Dominik; Alvarez-Erviti, Lydia; Bansal, Vikas; et al.
Xenobiotic- and Serum-Free Culture of Oral Mucosal Epithelial Cells on Contact Lenses
Current Eye Research, Vol. 41, (1) : 20-27
Björkblom, Benny; Eidet, Jon R.; Utheim, Tor P.; et al.
Metabolomic screening of pre-diagnostic serum samples identifies association between alpha- and gamma-tocopherols and glioblastoma risk
Oncotarget, Vol. 7, (24) : 37043-37053
Björkblom, Benny; Wibom, Carl; Jonsson, Pär; et al.
Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study
Tumor Biology, Vol. 37, (8) : 11065-11072
Späth, Florentin; Andersson, Ulrika; Dahlin, Anna M.; et al.
Reactive oxygen species-mediated DJ-1 monomerization modulates intracellular trafficking involving karyopherin beta 2
Molecular and Cellular Biology, Vol. 34, (16) : 3024-3040
Björkblom, Benny; Maple-Grødem, Jodi; Puno, Marc Rhyan; et al.
Parkinson Disease Protein DJ-1 Binds Metals and Protects against Metal-induced Cytotoxicity
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2013, Vol. 288, (31) : 22809-22820
Björkblom, Benny; Adilbayeva, Altynai; Maple-Grødem, Jodi; et al.
c-Jun N-Terminal Kinase Phosphorylation of MARCKSL1 Determines Actin Stability and Migration in Neurons and in Cancer Cells
Molecular and Cellular Biology, American Society for Microbiology 2012, Vol. 32, (17) : 3513-3526
Björkblom, Benny; Padzik, A.; Mohammad, H.; et al.
The prognostic value of MARCKS-like 1 in lymph node-negative breast cancer
Breast Cancer Research and Treatment, Springer 2012, Vol. 135, (2) : 381-390
Jonsdottir, Kristin; Zhang, Hui; Jhagroe, Darshni; et al.
Propidium monoazide combined with real-time quantitative PCR underestimates heat-killed Listeria innocua
Journal of Microbiological Methods, Elsevier 2011, Vol. 85, (2) : 164-169
Løvdal, Trond; Hovda, Maria Befring; Björkblom, Benny; et al.
Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate
Nature Neuroscience, Nature Publishing Group 2011, Vol. 14, (3) : 305-313
Westerlund, Nina; Zdrojewska, Justyna; Padzik, Artur; et al.
The Arabidopsis DJ-1a protein confers stress protection through cytosolic SOD activation
Journal of Cell Science, The Company of Biologists 2010, Vol. 123, (10) : 1644-1651
Xu, Xiang Ming; Lin, Hong; Maple, Jodi; et al.
Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin
Nature Neuroscience, Nature Publishing Group 2009, Vol. 12, (7) : 864-871
Morfini, Gerardo A; You, Yi-Mei; Pollema, Sarah L; et al.
Concurrent protective and destructive signaling of JNK2 in neuroblastoma cells
Cellular Signalling, Elsevier 2009, Vol. 21, (6) : 873-880
Waetzig, Vicki; Wacker, Ute; Haeusgen, Wiebke; et al.
All JNKs Can Kill, but Nuclear Localization Is Critical for Neuronal Death
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2008, Vol. 283, (28) : 19704-19713
Björkblom, Benny; Vainio, Jenni C.; Hongisto, Vesa; et al.
JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length
Journal of Cell Biology, Rockefeller University Press 2006, Vol. 173, (2) : 265-277
Tararuk, Tatsiana; Östman, Nina; Li, Wenrui; et al.
Constitutively Active Cytoplasmic c-Jun N-Terminal Kinase 1 Is a Dominant Regulator of Dendritic Architecture: Role of Microtubule-Associated Protein 2 as an Effector
Journal of Neuroscience, Society for Neuroscience 2005, Vol. 25, (27) : 6350-6361
Björkblom, Benny; Östman, Nina; Hongisto, Vesa; et al.
Thrombospondin 2 levels are increased in aged mice: consequences for cutaneous wound healing and angiogenesis
Matrix Biology, Elsevier 2004, Vol. 22, (7) : 539-547
Agah, Azin; Kyriakides, Themis R.; Letrondo, Nikole; et al.
Thrombospondin 2 Inhibits Microvascular Endothelial Cell Proliferation by a Caspase-independent Mechanism
Molecular Biology of the Cell, American Society for Cell Biology 2002, Vol. 13, (6) : 1893-1905
Armstrong, Lucas C.; Björkblom, Benny; Hankenson, Kurt D.; et al.
Diagnostic metabolic markers of glioma in blood for early detection
Jonsson, Sebastian; Antti, Henrik; Melin, Beatrice; et al.
Visa publikationer i DiVA

Forskargrupper

Gruppmedlem
Beatrice Melin
Henrik Antti Lab