Cecilia Hedenström Lindgren

Kontakt

090-786 93 69

Verksam som

Staff scientist vid Kemiska institutionen

KBC, Linnaeus väg 10, C4-33-07 Umeå universitet, 901 87 Umeå

Linker design principles for the precision targeting of oncogenic G-quadruplex DNA with G4-ligand-conjugated oligonucleotides

Bioconjugate chemistry, American Chemical Society (ACS) 2025, Vol. 36, (4) : 724-736

Abrahamsson, Alva; Berner, Andreas; Golebiewska-Pikula, Justyna; et al.

Structural basis of promiscuous inhibition of Listeria virulence activator PrfA by oligopeptides

Cell Reports, Elsevier 2025, Vol. 44, (2)

Hainzl, Tobias; Scortti, Mariela; Lindgren, Cecilia; et al.

Tolerogenic antigen-specific vaccine induces VISTA-enriched regulatory T cells and protects against arthritis in DRB1∗04:01 mice

Molecular Therapy

Romero-Castillo, Laura; Pandey, Rajan Kumar; Xu, Bingze; et al.

Enzyme dynamics determine the potency and selectivity of inhibitors targeting disease-transmitting mosquitoes

ACS - Infectious Diseases, American Chemical Society (ACS) 2024, Vol. 10, (10) : 3664-3680

Kumari, Rashmi; Lindgren, Cecilia; Kumar, Rajendra; et al.

Structure-function study of a Ca²⁺-independent metacaspase involved in lateral root emergence

Proceedings of the National Academy of Sciences of the United States of America, Proceedings of the National Academy of Sciences (PNAS) 2023, Vol. 120, (22)

Stael, Simon; Sabljić, Igor; Audenaert, Dominique; et al.

A highly substituted ring-fused 2-pyridone compound targeting PrfA and the efflux regulator BrtA in listeria monocytogenes

mBio, American Society for Microbiology 2023, Vol. 14, (3)

Tükenmez, Hasan; Singh, Pardeep; Sarkar, Souvik; et al.

Structure-activity relationships reveal beneficial selectivity profiles of inhibitors targeting acetylcholinesterase of disease-transmitting mosquitoes

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2023, Vol. 66, (9) : 6333-6353

Vidal-Albalat, Andreu; Kindahl, Tomas; Rajeshwari, Rajeshwari; et al.

Broad-Spectrum Antidote Discovery by Untangling the Reactivation Mechanism of Nerve-Agent-Inhibited Acetylcholinesterase

Chemistry - A European Journal, John Wiley & Sons 2022, Vol. 28, (40)

Lindgren, Cecilia; Forsgren, Nina; Hoster, Norman; et al.

Noncovalent Inhibitors of Mosquito Acetylcholinesterase 1 with Resistance-Breaking Potency

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2018, Vol. 61, (23) : 10545-10557

Knutsson, Sofie; Engdahl, Cecilia; Kumari, Rashmi; et al.

Dynamics Determine Signaling in a Multicomponent System Associated with Rheumatoid Arthritis

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2018, Vol. 61, (11) : 4774-4790

Lindgren, Cecilia; Tyagi, Mohit; Viljanen, Johan; et al.

Design strategies for new drugs targeting multicomponent systems: focusing on class II MHC proteins and acetylcholinesterase

Umeå: Umeå universitet 2017

Lindgren, Cecilia

Benefits of statistical molecular design, covariance analysis, and reference models in QSAR: a case study on acetylcholinesterase

Journal of Computer-Aided Molecular Design, Vol. 29, (3) : 199-215

Andersson, C. David; Hillgren, J. Mikael; Lindgren, Cecilia; et al.

Hydroxyethylene isosteres introduced in type II collagen fragments substantially alter the structure and dynamics of class II MHC A(q)/glycopeptide complexes

Organic and biomolecular chemistry, Vol. 13, (22) : 6203-6216

Lindgren, Cecilia; Andersson, Ida E.; Berg, Lotta; et al.

Towards precision in designing broad-spectrum acetylcholinesterase reactivators: a study of oxime reactivators and peripheral site moieties

Hoster, Norman; Lindgren, Cecilia; Forsgren, Nina; et al.

Design of Reactive Drugs: Structure and Mechanism of Novel Nerve Agent Antidotes

Lindgren, Cecilia; Forsgren, Nina; Akfur, Christine; et al.

Modification of a Fragment from Type II Collagen Affects the Dynamics of Human Class II MHC Proteins and the Subsequent T-Cell Response, Associated with Rheumatoid Arthritis

Lindgren, Cecilia; Tyagi, Mohit; Viljanen, Johan; et al.

Hydrophobic recognition allows transcription factor PrfA from Listeria monocytogenes to bind peptides of different sequences and lengths

Oelker, Melanie; Lindgren, Cecilia; Grundström, Christin; et al.

Discovery of three new binding sites and modes of ring-fused 2-pyridones to PrfA: How can they contribute to drug design?

Oelker, Melanie; Vielfort, Katarina; Lindgren, Cecilia; et al.

Discovery of inhibitors and activators targeting metacaspases of the parasite Trypanosoma brucei

Rajeshwari, Rajeshwari; Boström, Emelie; Lindgren, Cecilia; et al.

Potent and selective indole-based inhibitors targeting disease-transmitting mosquitoes

Rajeshwari, Rajeshwari; Lindgren, Cecilia; Duvauchelle, Valentine; et al.

Exploring acetylcholinesterase of honey bees: how to avoid off-target effects of insecticides

Rajeshwari, Rajeshwari; Lindgren, Cecilia; Springer Engdahl, Cecilia; et al.

Visa publikationer i DiVA

Forskargrupper

Gruppmedlem

Anna Linusson Lab

Forskningsprojekt

1 januari 2020 till 31 december 2023

Utforskande om de molekylära mekanismer som styr bakteriell virulens