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Umeå universitet
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Huvudmenyn dold.
Personalbild Sara Wilson

Sara Wilson

Universitetslektor i fysiologi, PhD, docent, meriterad lärare. Forskning om nervsystemet under utveckling och sjukdom.

Vetenskaplig meritering: Docent
Pedagogisk meritering: Meriterad lärare

Kontakt

E-post
sara.wilson@umu.se
Telefon
090-786 93 78

Verksam som

Anknytning
Universitetslektor vid Institutionen för medicinsk och translationell biologi Enhet: Lärare D1-flygeln, Grupp Sara Wilson
Plats
hus H, Johan Bures väg 12, Biologihuset Umeå universitet, 901 87 Umeå

Målsättningen med vår forskning är att utreda nervsystemets utveckling med fokus på etablering och tillväxt, sammansättning och förbindelser under normala förhållanden och sjukdomsprocesser, såsom cancer och neurologiska utvecklingsavvikelser. Informationen från våra grundläggande upptäckter används sedan i prekliniska modeller för att identifiera nya mål för att behandla sjukdomar, som exempelvis cancer.

Sara Wilson: biographical information

Hemsida

Dysregulation of core neurodevelopmental pathways: a common feature of cancers with perineural invasion
Frontiers in Genetics, Frontiers Media S.A. 2023, Vol. 14
Gonzalez-Castrillon, Luz Maria; Wurmser, Maud; Öhlund, Daniel; et al.
Alternative LIM homeodomain splice variants are dynamically regulated at key developmental steps in vertebrates
Developmental Dynamics, American Association for Anatomy 2022, Vol. 251, (7) : 1223-1243
Wheaton, Benjamin Joel; Häggström, Sara Lea; Muppavarapu, Mridula; et al.
Robo2 Receptor Gates the Anatomical Divergence of Neurons Derived From a Common Precursor Origin
Frontiers in Cell and Developmental Biology, Frontiers Media S.A. 2021, Vol. 9
Wurmser, Maud; Muppavarapu, Mridula; Tait, Christine Mary; et al.
Evolution of the functionally conserved DCC gene in birds
Scientific Reports, Macmillan Publishers Ltd. 2017, Vol. 7
Patthey, Cedric; Tong, Yong Guang; Tait, Christine Mary; et al.
Commissural axonal corridors instruct neuronal migration in the mouse spinal cord
Nature Communications, Vol. 6
Laumonnerie, Christophe; Tong, Yong Guang; Alstermark, Helena; et al.
Netrin 1 and Dcc signalling are required for confinement of central axons within the central nervous system
Development, Vol. 141, (3) : 594-603
Laumonnerie, Christophe; Da Silva, Ronan V.; Kania, Artur; et al.
The expression profile of the tumor suppressor gene Lzts1 suggests a role in neuronal development
Developmental Dynamics, Vol. 241, (5) : 984-994
Kropp, Marlene; Wilson, Sara I.
Target practice: Zic2 hits the bullseye!
EMBO Journal, Nature Publishing Group 2010, Vol. 29, (18) : 3037-3038
Wilson, Sara I
A molecular program for contralateral trajectory: Rig-1 control by LIM homeodomain transcription factors.
Neuron, Vol. 59, (3) : 413-24
Wilson, Sara Ivy; Shafer, Beth; Lee, Kevin J; et al.
Neural induction: toward a unifying mechanism
Nature Neuroscience, Nature Publishing Group 2001 : 1161-1168
Wilson, Sara I; Edlund, Thomas
The status of Wnt signalling regulates neural and epidermal fates in the chick embryo.
Nature, Vol. 411, (6835) : 325-30
Wilson, Sara I; Rydström, A; Trimborn, T; et al.
An early requirement for FGF signalling in the acquisition of neural cell fate in the chick embryo.
Current Biology, Vol. 10, (8) : 421-9
Wilson, Sara I; Graziano, E; Harland, R; et al.
Convergent inductive signals specify midbrain, hindbrain, and spinal cord identity in gastrula stage chick embryos.
Neuron, Vol. 23, (4) : 689-702
Muhr, J; Graziano, E; Wilson, Sara I; et al.
Sensitivity to inhibition and catalytic efficiency of HIV proteinase mutants.
Advances in Experimental Medicine and Biology, Vol. 436 : 85-9
Wilson, Sara I; Phylip, L H; Gulnik, S V; et al.
Escape mutants of HIV-1 proteinase: enzymic efficiency and susceptibility to inhibition
Biochimica et Biophysica Acta, Vol. 1339, (1) : 113-125
Wilson, Sara I; Phylip, L H; Mills, J S; et al.
Bindings of mutant HIV-I proteases with junction B peptides containing methyleneamino isostere replacements
Protein and Peptide Letters, Bentham Science Publishers 1997, Vol. 4 : 225-235
Zhang, L; Pennington, M.W; Baur, P; et al.
GAP junction B family dysregulation in pancreatic cancer
Wurmser, Maud; González-Castrillón, Luz María; Öhlund, Daniel; et al.
Visa publikationer i DiVA

Forskargrupper

Forskningsledare
Sara Wilson lab