Ulf Ahlgren

Jag forskar inom området molekylär medicin. Mitt specialområde är avbildningsteknologier för att studera diabetes.

Kontakt

ulf.ahlgren@umu.se

090-786 50 55, 070-220 92 28

Verksam vid

Professor vid Umeå centrum för molekylär medicin (UCMM)

MBC, vån 4, B-flygeln, Johan Bures Väg 12, B-425 Umeå universitet, 901 87 Umeå

Läs mer om Ulf Ahlgrens forskargrupp

Mesoscopic Optical Imaging of the Pancreas: Revisiting Pancreatic Anatomy and Pathophysiology

Frontiers in Endocrinology, Frontiers Media S.A. 2021, Vol. 12

Alanentalo, Tomas; Hahn, Max; Willekens, Stefanie M. A.; et al.

Insights into the etiology and physiopathology of MODY5/HNF1B pancreatic phenotype with a mouse model of the human disease

Journal of Pathology

Quilichini, Evans; Fabre, Mélanie; Nord, Christoffer; et al.

Novel Strategies to Protect and Visualize Pancreatic beta Cells in Diabetes

Trends in endocrinology and metabolism, Elsevier 2020, Vol. 31, (12) : 905-917

Gurzov, Esteban N.; Ke, Pu Chun; Ahlgren, Ulf; et al.

Mesoscopic 3D imaging of pancreatic cancer and Langerhans islets based on tissue autofluorescence

Scientific Reports, Springer Nature 2020, Vol. 10, (1)

Hahn, Max; Nord, Christoffer; Franklin, Oskar; et al.

Topologically selective islet vulnerability and self-sustained downregulation of markers for β-cell maturity in streptozotocin-induced diabetes

Communications Biology, Nature Publishing Group 2020, Vol. 3, (1)

Hahn, Max; van Krieken, Pim P.; Nord, Christoffer; et al.

The effect of hypergastrinemia following sleeve gastrectomy and pantoprazole on type 2 diabetes mellitus and beta-cell mass in Goto-Kakizaki rats

Journal of Endocrinological Investigation, Springer 2018, Vol. 41, (6) : 691-701

Grong, E.; Nord, Christoffer; Arbo, I. B.; et al.

Early deficits in insulin secretion, beta cell mass and islet blood perfusion precede onset of autoimmune type 1 diabetes in BioBreeding rats

Diabetologia, Springer 2018, Vol. 61, (4) : 896-905

Medina, Anya; Parween, Saba; Ullsten, Sara; et al.

Biochemical profiling of diabetes disease progression by multivariate vibrational microspectroscopy of the pancreas

Scientific Reports, Nature Publishing Group 2017, Vol. 7

Nord, Christoffer; Eriksson, Maria; Dicker, Andrea; et al.

Spatial and quantitative datasets of the pancreatic beta-cell mass distribution in lean and obese mice

Scientific Data, Vol. 4

Parween, Saba; Eriksson, Maria; Nord, Christoffer; et al.

Kinetics of functional beta cell mass decay in a diphtheria toxin receptor mouse model of diabetes

Scientific Reports, NATURE PUBLISHING GROUP 2017, Vol. 7

van Krieken, Pim P.; Dicker, Andrea; Eriksson, Maria; et al.

SPECT-OPT multimodal imaging enables accurate evaluation of radiotracers for beta-cell mass assessments

Scientific Reports, Vol. 6

Eter, Wael A.; Parween, Saba; Joosten, Lieke; et al.

Sleeve gastrectomy, but not duodenojejunostomy, preserves total beta-cell mass in Goto-Kakizaki rats evaluated by three-dimensional optical projection tomography

Surgical Endoscopy, Vol. 30, (2) : 532-542

Grong, Eivind; Kulseng, Bård; Arbo, Ingerid Brænne; et al.

Intra-islet lesions and lobular variations in β-cell mass expansion in ob/ob mice revealed by 3D imaging of intact pancreas

Scientific Reports, Nature Publishing Group 2016, Vol. 6

Parween, Saba; Kostromina, Elena; Nord, Christoffer; et al.

The pancreas

Kaufman's atlas of mouse development supplement: with coronal sections, Elsevier 2015 : 85-94

Hörnblad, Andreas; Nord, Christoffer; Parween, Saba; et al.

Light scattering as an intrinsic indicator for pancreatic islet cell mass and secretion

Scientific Reports, Vol. 5

Ilegems, E.; van Krieken, P. P.; Edlund, P. K.; et al.

A novel mouse model of tuberous sclerosis complex (TSC): eye-specific Tsc1-ablation disrupts visual-pathway development

Disease Models and Mechanisms, Vol. 8, (12) : 1517-1529

Jones, Iwan; Hägglund, Anna-Carin; Törnqvist, Gunilla; et al.

Targeted Disruption of ALK Reveals a Potential Role in Hypogonadotropic Hypogonadism

PLOS ONE, Vol. 10, (5)

Witek, Barbara; El Wakil, Abeer; Nord, Christoffer; et al.

Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice

Nature Biotechnology, Vol. 32, (1) : 76-83

Baeyens, Luc; Lemper, Marie; Leuckx, Gunter; et al.

Differential regulation of myosin heavy chains defines new muscle domains in zebrafish

Molecular Biology of the Cell, American Society for Cell Biology 2014, Vol. 25, (8) : 1384-1395

Nord, Hanna; Burguiere, Anne-Cecile; Muck, Joscha; et al.

Imaging shows insulin-producing cells in diabetes

TrAC. Trends in analytical chemistry, Vol. 44 : III-III

Ahlgren, Ulf

Improving signal detection in emission optical projection tomography via single source multi-exposure image fusion

Optics Express, Optical Society of America 2013, Vol. 21, (14) : 16584-16604

Cheddad, Abbas; Nord, Christoffer; Hörnblad, Andreas; et al.

Near infrared optical projection tomography for assessments of beta-cell mass distribution in diabetes research

Journal of Visualized Experiments, Vol. 71

Eriksson, Anna U.; Svensson, Christoffer; Hörnblad, Andreas; et al.

The fractal spatial distribution of pancreatic islets in three dimensions: a self-avoiding growth model

Physical Biology, Institute of Physics Publishing (IOPP) 2013, Vol. 10, (3) : 036009-

Jo, Junghyo; Hörnblad, Andreas; Kilimnik, German; et al.

Neurogenin 3(+) cells contribute to beta-cell neogenesis and proliferation in injured adult mouse pancreas

Cell Death and Disease, London: Nature Publishing Group 2013, Vol. 4 : e523-

Van de Casteele, M.; Leuckx, G.; Baeyens, L.; et al.

Exploring the pancreas with optical projection tomography

Imaging in Medicine, Vol. 4, (1) : 5-7

Ahlgren, Ulf

Image processing assisted algorithms for optical projection tomography

IEEE Transactions on Medical Imaging, Vol. 31, (1) : 1-15

Cheddad, Abbas; Svensson, Christoffer; Sharpe, James; et al.

Mathematical models of pancreatic islet size distributions

Islets, Landes bioscience 2012, Vol. 4, (1) : 10-19

Jo, Junghyo; Hara, Manami; Ahlgren, Ulf; et al.

The role of Raf-1 kinase inhibitor protein in the regulation of pancreatic beta cell proliferation in mice.

Diabetologia, Vol. 55, (12) : 3331-40

Pardo, F N; Altirriba, J; Pradas-Juni, M; et al.

Imaging the pancreatic beta cell: chapter 13

Type 1 diabetes: pathogenesis, genetics and immunotherapy

Ahlgren, Ulf; Kostromina, Elena

An improved protocol for optical projection tomography imaging reveals lobular heterogeneities in pancreatic islet and β-cell mass distribution

Islets, Austin: Landes Bioscience 2011, Vol. 3, (4) : 204-208

Hörnblad, Andreas; Cheddad, Abbas; Ahlgren, Ulf

Impaired spleen formation perturbs morphogenesis of the gastric lobe of the pancreas

PLOS ONE, San Francisco, CA: Public Library of Science 2011, Vol. 6, (6) : e21753-

Hörnblad, Andreas; Eriksson, Anna; Sock, Elisabeth; et al.

Growth-limiting role of endothelial cells in endoderm development

Developmental Biology, Academic Press 2011, Vol. 352, (2) : 267-277

Sand, Fredrik Wolfhagen; Hörnblad, Andreas; Johansson, Jenny K; et al.

Approaches for imaging islets

Advances in Experimental Medicine and Biology, Springer Netherlands 2010, Vol. 654 : 39-57

Ahlgren, Ulf; Gotthardt, Martin

Quantification and 3-D imaging of the insulitis-induced destruction of β-cells in murine type 1 diabetes

Diabetes, Vol. 59, (7) : 1756-1764

Alanentalo, Tomas; Hörnblad, Andreas; Mayans, Sofia; et al.

Optical imaging of islets: new possibilities by the development of infrared fluorescent proteins

Islets, Vol. 1, (2) : 163-164

Ahlgren, Ulf; Hörnblad, Andreas

FGF signals induce Caprin2 expression in the vertebrate lens.

Differentiation, Vol. 77, (4) : 386-394

Lorén, Christina E; Schrader, John W; Ahlgren, Ulf; et al.

High-resolution three-dimensional imaging of islet-infiltrate interactions based on optical projection tomography assessments of the intact adult mouse pancreas

Journal of Biomedical Optics, Bellingham, WA: SPIE--the International Society for Optical Engineering 2008, Vol. 13, (5) : 054070-

Alanentalo, Tomas; Lorén, Christina E; Larefalk, Asa; et al.

Imaging the pancreas: from ex vivo to non-invasive technology.

Diabetologia, Vol. 51, (12) : 2148-2154

Holmberg, Dan; Ahlgren, Ulf

Tomographic molecular imaging and 3D quantification within adult mouse organs.

Nature Methods, Vol. 4, (1) : 31-33

Alanentalo, Tomas; Asayesh, Amir; Morrison, Harris; et al.

Spleen versus pancreas: strict control of organ interrelationship revealed by analyses of Bapx1-/- mice.

Genes & Development, Vol. 20, (16) : 2208-2213

Asayesh, Amir; Sharpe, James; Watson, Robert P; et al.

Developmental expression of metalloproteases ADAM 9, 10, and 17 becomes restricted to divergent pancreatic compartments.

Developmental Dynamics, Vol. 232, (4) : 1105-1114

Asayesh, Amir; Alanentalo, Tomas; Khoo, Nelson K S; et al.

Nuclear factor-{kappa}B activity in {beta}-cells is required for glucose-stimulated insulin secretion.

Diabetes, Vol. 54, (1) : 125-32

Norlin, Stefan; Ahlgren, Ulf; Edlund, Helena

The splanchnic mesodermal plate directs spleen and pancreatic laterality, and is regulated by Bapx1/Nkx3.2.

Development, Vol. 131, (19) : 4665-75

Hecksher-Sørensen, Jacob; Watson, Robert P; Lettice, Laura A; et al.

Visa publikationer i DiVA

Forskargrupper

Forskningsledare

Ulf Ahlgren

Publicerad: 30 sep, 2020

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