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Umeå Centre for Electron Microscopy (UCEM)

Research infrastructure Umeå Centre for Electron Microscopy (UCEM) is a university and national resource for research and higher education in electron microscopy techniques.

Electron microscopy is used for the structural, physical, chemical, and functional characterisation at micro- and nanometre scales. UCEM supports research projects from all research disciplines. Medical, biological and soft samples are prepared specifically for electron microscopy imaging and analysis. Structural biology projects are addressed by cryogenic electron microscopy (cryo-EM) and advanced computational image processing. Electron tomography and volume imaging capabilities at UCEM bridge from sample preparation, multi-instrument data collection, computational reconstruction, to visualisation.

UCEM hosts the SciLifeLab Cellular and Molecular Imaging platform in Umeå. Together with the Biochemical Imaging Centre Umeå (BICU) and researchers, UCEM supports correlative light and electron microscopy (CLEM) projects and method development.

Aims of the centre are:

• Provide high-quality research project support and service for sample preparation, scanning electron microscopy (SEM), transmission electron microscopy (TEM), as well as computational image processing.
• Offer basic and advanced practical courses, workshops, and training in electron microscopy.
• Assist interdisciplinary research activities and develop advanced methodologies for applications and projects with electron microscopy.

SEM

Scanning Electron Microscopy

TEM

Transmission Electron Microscopy

Leica Ultra microtomes
Sample preparation

Sample preparation equipment

Cryo-EM

Cryo-Electron Microscopy

CLEM

Correlative Light and Electron Microscopy

Diffraction pattern of sugar from a Glacios electron microscope at UCEM, Umeå Center for Electron Microscopy.
MicroED

3D structure determination using electron diffraction

Latest update: 2025-04-28