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Umeå universitet
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Huvudmenyn dold.
Personalbild Anna Södergren

Anna Södergren

Universitetslektor och överläkare i reumatologi

Vetenskaplig meritering: Docent
0000-0002-7436-7900

Kontakt

E-post
anna.sodergren@umu.se
Telefon
090-786 58 20

Verksam som

Anknytning
Universitetslektor, överläkare vid Institutionen för folkhälsa och klinisk medicin Enhet: Reumatologi
Plats
Byggnad 1A, plan 4, målpunkt B41, Norrlands universitetssjukhus

Inflammatoriska reumatologiska sjukdomar uppträder hos flera procent av befolkningen. Reumatoid artrit (RA) är den vanligaste, med en prevalens på 0,5-1%. För spondartriter, som bland annat innefattar psoriasisartrit (PsA) och ankyloserande spondylit (AS), beräknas prevalensen vara omkring 0,5% för varje sjukdom. Idag är en ökad förekomst av samsjuklighet såsom kardiovaskulär sjukdom och lungsjukdom hos patienter med reumatologiska sjukdomar välkänd. Hur utvecklingen skiljer sig från den i den allmänna befolkningen har inte fastställts.

Syftet med mina vidare studier är att studera epidemiologin bakom, patogenetiska faktorer för och utfallet efter denna samsjuklighet hos patienter med inflammatoriska reumatologiska sjukdomar. Vidare ingår i min forskning studier på behandling av den reumatologiska sjukdomen samt hur livsstilsfaktorer såsom kost och motion kan påverka hälsan hos patienter med reumatologiska sjukdomar. Sammantaget kan dessa studier öka möjligheten till förebyggande av samsjuklighet och därmed minskat lidande och ökad livskvalitet hos dessa patienter.

Cohort study of serological biomarkers for interstitial lung disease in patients with rheumatoid arthritis
Scandinavian Journal of Rheumatology, Taylor & Francis 2024, Vol. 53, (6) : 386-395
Colmenares, Vania; Hedman, A.; Hesslow, A.; et al.
The serological immunogenicity of the third and fourth doses of COVID-19 vaccine in patients with inflammatory rheumatic diseases on different biologic or targeted DMARDs: a Swedish nationwide study (COVID-19-REUMA)
Microbiology Spectrum, Vol. 12, (4)
Frodlund, Martina; Nived, Per; Chatzidionysiou, Katerina; et al.
Associations between serological biomarkers and subclinical atherosclerosis in patients with rheumatoid arthritis after 11 years of follow-up
Clinical and Experimental Rheumatology, Clinical and Experimental Rheumatology 2024, Vol. 42, (5) : 967-973
Hofstedt, Oscar E.; Wahlin, Bengt; Södergren, Anna
Heart rate variability and cardiovascular risk factors in patients with rheumatoid arthritis: a longitudinal study
Autonomic Neuroscience: Basic & Clinical, Elsevier 2023, Vol. 249
Erelund, Sofia; Södergren, Anna; Wiklund, Urban; et al.
The impact of immunomodulating treatment on the immunogenicity of COVID-19 vaccines in patients with immune-mediated inflammatory rheumatic diseases compared to healthy controls. A Swedish nationwide study (COVID19-REUMA)
Vaccine, Elsevier 2023, Vol. 41, (20) : 3247-3257
Frodlund, Martina; Nived, Per; Chatzidionysiou, Aikaterini; et al.
Individual regression modelling of spinal mobility measurements in long-term ankylosing spondylitis: In-depth analyses with comparison to norm data
Arthritis care & research, John Wiley & Sons 2023, Vol. 75, (4) : 793-800
Hörnberg, Kristina; Ljung, Lotta; Södergren, Anna; et al.
Time trends of cardiovascular disease in the general population and inflammatory arthritis
Rheumatic Disease Clinics of North America, Elsevier 2023, Vol. 49, (1) : 1-17
Södergren, Anna; Rantapää-Dahlqvist, Solbritt; Ljung, Lotta
Rheumatoid cachexia in early rheumatoid arthritis: prevalence and associated variables
Scandinavian Journal of Rheumatology, Taylor & Francis 2023, Vol. 52, (1) : 10-16
Ångström, Lars; Hörnberg, Kristina; Sundström, Björn; et al.
Isotemporal Substitution of Time Between Sleep and Physical Activity: Associations With Cardiovascular Risk Factors in Early Rheumatoid Arthritis
ACR Open Rheumatology, John Wiley & Sons 2021, Vol. 3, (3) : 138-146
Hörnberg, Kristina; Pomeroy, Jeremy; Sandberg, Camilla; et al.
Characteristics and outcome of a first acute myocardial infarction in patients with ankylosing spondylitis
Clinical Rheumatology, Springer 2021, Vol. 40 : 1321-1329
Södergren, Anna; Askling, Johan; Bengtsson, Karin; et al.
Atherosclerosis in rheumatoid arthritis: associations between anti-cytomegalovirus IgG antibodies, CD4+CD28null T-cells, CD8+CD28null T-cells and intima-media thickness
Clinical and Experimental Rheumatology, Clinical and Experimental Rheumatology S.A.S. 2021, Vol. 39, (3) : 578-586
Wahlin, Bengt; Fasth, Andreas; Karp, Kjell; et al.
Osteoprotegerin and osteocalcin are associated with atherosclerosis in patients with rheumatoid arthritis: a prospective cohort study
Clinical and Experimental Rheumatology, Vol. 39, (6) : 1402-1409
Wahlin, Bengt; Ramnemark, Anna; Rantapää-Dahlqvist, Solbritt; et al.
Response to: "Influence of changes in cholesterol levels and disease activity on the 10-year cardiovascular risk estimated with different algorithms in rheumatoid arthritis patients" by Fornaro et al
Annals of the Rheumatic Diseases, BMJ Publishing Group Ltd 2020, Vol. 79, (9)
Agca, Rabia; Heslinga, Sjoerd C.; Rollefstad, S.; et al.
Extent of atherosclerosis after 11-year prospective follow-up in patients with early rheumatoid arthritis was affected by disease severity at diagnosis
Scandinavian Journal of Rheumatology, Taylor & Francis 2020, Vol. 49, (6) : 443-451
Björsenius, I; Rantapää-Dahlqvist, Solbritt; Berglin, Ewa; et al.
Physical activity in rheumatoid arthritis: relationship to cardiovascular risk factors, subclinical atherosclerosis, and disease activity
Scandinavian Journal of Rheumatology, Taylor & Francis Group 2020, Vol. 49, (2) : 112-121
Hörnberg, Kristina; Pomeroy, J.; Sandberg, Camilla; et al.
Aerobic capacity is associated with disease activity and cardiovascular risk factors in early rheumatoid arthritis
Physiotherapy Research International, John Wiley & Sons 2020, Vol. 25, (3)
Ångström, Lars; Hörnberg, Kristina; Sundström, Björn; et al.
Biomarkers associated with cardiovascular disease in patients with early rheumatoid arthritis
PLOS ONE, Public Library of Science 2019, Vol. 14, (8)
Södergren, Anna; Karp, Kjell; Bengtsson, Christine; et al.
Increased progression of atherosclerosis in patients with rheumatoid arthritis is partially reflected by disease severity at the time of diagnosis: 11-year prospective follow-up
Scandinavian Journal of Rheumatology, Taylor & Francis 2018, Vol. 47 : 20-21
Bjorsenius, I.; Rantapää-Dahlqvist, Solbritt; Wållberg-Jonsson, Solveig; et al.
Case fatality over 365 days after first acute coronary syndrome in patients with ankylosing spondylitis
Annals of the Rheumatic Diseases, BMJ Publishing Group Ltd 2018, Vol. 77 : 341-341
Södergren, Anna; Askling, J.; Bengtsson, K.; et al.
EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update
Annals of the Rheumatic Diseases, Vol. 76, (1) : 17-28
Agca, R.; Heslinga, S. C.; Rollefstad, S.; et al.
High concentrations of Angiopoietin-like Protein 4 detected in serum from patients with rheumatoid arthritis can be explained by non-specific antibody reactivity
PLOS ONE, Vol. 12, (1)
Makoveichuk, Elena; Ruge, Toralph; Nilsson, Solveig; et al.
Cd8+cd28- t-lymphocytes are associated with subclinical atherosclerosis in patients with rheumatoid arthritis
Annals of the Rheumatic Diseases, BMJ PUBLISHING GROUP 2017, Vol. 76 : 250-250
Wahlin, Bengt; Fasth, A. E.; Karp, Kjell; et al.
Co-morbidity in patients with early rheumatoid arthritis - inflammation matters
Arthritis Research & Therapy , BioMed Central 2016, Vol. 18
Innala, Lena; Sjöberg, Clara; Möller, Bozena; et al.
The Extent of Subclinical Atherosclerosis Is Partially Predicted by the Inflammatory Load: A Prospective Study over 5 Years in Patients with Rheumatoid Arthritis and Matched Controls
Journal of Rheumatology, Vol. 42, (6) : 935-942
Södergren, Anna; Karp, Kjell; Bengtsson, Christine; et al.
Is Lipoprotein-Associated Phospholipase A2a Link between Inflammation and Subclinical Atherosclerosis inRheumatoid Arthritis?
BioMed Research International
Södergren, Anna; Karp, Kjell; Bengtsson, Christine; et al.
Age at onset determines severity and choice of treatment in early rheumatoid arthritis: a prospective study
Arthritis Research & Therapy , BioMed Central 2014, Vol. 16, (2) : R94-
Innala, Lena; Berglin, Ewa; Möller, Bozena; et al.
Comorbidity in early rheumatoid arthritis - which is the role of inflammation?
Annals of the Rheumatic Diseases, Vol. 73 : 406-406
Innala, Lena; Sjöberg, C.; Berglin, Eva; et al.
Screening and simple counselling affect traditional cardiovascular risk factors in patients with early rheumatoid arthritis
Scandinavian Journal of Rheumatology, Informa Healthcare 2014, Vol. 43, (Suppl. 127 Meeting Abstract PP234) : 76-76
Isaksson, J.; Wållberg-Jonsson, Solveig; Alenius, Gerd-Marie; et al.
Circulating plasma levels of cathepsin S and L are not associated with disease severity in patients with rheumatoid arthritis
Scandinavian Journal of Rheumatology, Vol. 43, (5) : 371-373
Ruge, Toralph; Södergren, Anna; Wallberg-Jonsson, Solveig; et al.
Comorbidity in early rheumatoid arthritis: does inflammation matter?
Arthritis and Rheumatism, Wiley-Blackwell 2013, Vol. 65, (Special issue, Supplement 10) : S176-S176, Meeting Abstract: 408
Innala, Lena; Sjöberg, Clara; Berglin, Ewa H; et al.
Age at onset determines severity and choice of treatment in early rheumatoid arthritis
Arthritis and Rheumatism, John Wiley & Sons 2012, Vol. 64, (10) : S908-S908
Innala, Lena; Möller, Bozena; Ljung, Lotta; et al.
Progression of subclinical atherosclerosis over 5 years in patients with early rheumatoid arthritis
Annals of the Rheumatic Diseases, Vol. 71 : A92-A92
Wållberg-Jonsson, Solveig; Karp, Kjell; Boman, Kurt; et al.
Cardiovascular events in early rheumatoid arthritis (RA) are a result of inflammatory burden and traditional risk factors: a five year prospective study
Arthritis Research & Therapy , Vol. 13, (4) : R131-
Innala, Lena; Möller, Bozena; Ljung, Lotta; et al.
Atherosclerosis in early rheumatoid arthritis: very early endothelial activation and rapid progression of intima media thickness
Arthritis Research & Therapy , Vol. 12, (4) : R158-
Södergren, Anna; Karp, Kjell; Boman, Kurt; et al.
Atherothrombotic events in rheumatoid arthritis are predicted by homocysteine: a six-year follow-up study
Clinical and Experimental Rheumatology, Vol. 27, (5) : 822-825
Berglund, S; Södergren, Anna; Wållberg Jonsson, Solveig; et al.
Increased incidence of stroke and impaired prognosis after stroke among patients with seropositive rheumatoid arthritis
Clinical and Experimental Rheumatology, Vol. 27, (4) : 641-644
Södergren, Anna; Stegmayr, Birgitta; Öhman, Marie-Louise; et al.
Increased incidence of and impaired prognosis after acute myocardial infarction among patients with seropositive rheumatoid arthritis.
Annals of the Rheumatic Diseases, BMJ Publishing Group Ltd & European League Against Rheumatism 2007, Vol. 66, (2) : 263-266
Södergren, Anna; Stegmayr, Birgitta; Lundberg, Vivan; et al.
Comorbidity in patients with early rheumatoid arthritis: does inflammation matter?
Innala, Lena; Sjöberg, C; Möller, B; et al.
Significant Increase of intima media thickness in eighteen months among patients with newly diagnosed rheumatoid arthritis
Södergren, Anna; Karp, K.; Boman, K.; et al.
No signs of premature atherosclerosis in early rheumatoid arthritis albeit endothelial biomarkers are upregulated
Södergren, Anna; Karp, K.; Boman, K.; et al.
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Ämnesansvarig för reumatologi

Undervisar huvudsakligen på läkarprogrammets termin 8 men även på andra utbildningar såsom arbetsterapeutprogrammet

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Sjuka leder och sjukt hjärta - har de något gemensamt?

Anna Södergren berättar om vad ledgångsreumatism har gemensamt med stroke och hjärtinfarkt.