Jan Malm

Professor Jan Malm är neurolog och överläkare. Forskningsintresset är fokuserat på olika aspekter av hydrocefalus, likvordynamik, blodflödesmätning, och intrakraniellt tryck hos astronauter.

Kontakt

jan.malm@umu.se

090-786 50 97

Verksam som

Professor vid Institutionen för klinisk vetenskap Enhet: Neurovetenskaper

Norrlands universitetssjukhus, Klinisk vetenskap/Neurovetenskaper, E14 By 10, Trappa E, vån1 Umeå universitet, Klinisk vetenskap, 901 85 Umeå

Relaxivity of gadobutrol and gadoteric acid in cerebrospinal fluid at 3T

Magnetic Resonance in Medicine, John Wiley & Sons 2026, Vol. 95, (6) : 3409-3415

Behndig, Sofia; Garpebring, Anders; Dahlgren Lindström, Daniel; et al.

CSF Aquaporin-4 levels in controls and in idiopathic normal pressure hydrocephalus before and after shunt surgery

Fluids and Barriers of the CNS, BioMed Central (BMC) 2026, Vol. 23, (1)

Eriksson De Ryst, Johan; Bergström, Sofia; Mravinacova, Sara; et al.

Intracranial pressure dynamics and cerebrospinal fluid outflow resistance in the elderly: associations with 10-year changes in cognitive function and ventricular volume

Neurosurgery

Hansson, William; Qvarlander, Sara; Eklund, Sanna Andrea; et al.

Quantifying cardiac, respiratory, and low frequency components of CSF motion from fMRI inflow effects

Magnetic Resonance in Medicine

Söderström, Pontus; Björnfot, Cecilia; Andersson, Britt M.; et al.

The next era of idiopathic normal pressure hydrocephalus

JAMA Neurology, American Medical Association (AMA) 2026, Vol. 83, (4) : 307-308

Williams, Michael A.; Luciano, Mark G.; Malm, Jan; et al.

Quantitative assessment of flow between cerebrospinal and interstitial fluid compartments in humans

Proceedings of the National Academy of Sciences of the United States of America, Proceedings of the National Academy of Sciences (PNAS) 2026, Vol. 123, (18)

Wåhlin, Anders; Behndig, Sofia; Eriksson De Ryst, Johan; et al.

qDESH: a method to quantify disproportionately enlarged subarachnoid space hydrocephalus

Fluids and Barriers of the CNS, Vol. 22, (1)

Behndig, Sofia; Lalou, Afroditi D.; Axelsson, Jan; et al.

Higher-level gait disorders: a population-based study on prevalence, quality of life, depression and confidence in gait and balance

BMJ Neurology Open, BMJ Publishing Group Ltd 2025, Vol. 7, (1)

Larsson, Jenny; Hansson, William; Israelsson Larsen, Hanna; et al.

A randomized trial of shunting for idiopathic normal-pressure hydrocephalus

New England Journal of Medicine, Massachusetts Medical Society 2025, Vol. 393, (22) : 2198-2209

Luciano, Mark G.; Williams, Michael A.; Hamilton, Mark G.; et al.

An optimized ensemble search approach for classification of higher-level gait disorder using brain magnetic resonance images

Computers in Biology and Medicine, Elsevier 2025, Vol. 184

Mogensen, Klara; Guarrasi, Valerio; Larsson, Jenny; et al.

Respiratory influence on cerebral blood flow and blood volume: a 4D flow MRI study

Journal of Cerebral Blood Flow and Metabolism, Sage Publications 2025, Vol. 45, (8) : 1531-1542

Söderström, Pontus; Eklund, Anders; Karalija, Nina; et al.

MRI contrast accumulation in features of cerebral small vessel disease: blood-brain barrier dysfunction or elevated vascular density?

Fluids and Barriers of the CNS, BioMed Central (BMC) 2025, Vol. 22, (1)

Vikner, Tomas; Garpebring, Anders; Björnfot, Cecilia; et al.

Non-invasive assessment of cerebral perfusion pressure: Applied towards preoperative planning of aortic arch surgery with selective antegrade cerebral perfusion

Journal of Biomechanics, Elsevier 2025, Vol. 179

Vikström, Axel; Eklund, Anders; Johannesdottir, Martha; et al.

Arterial-optimized 4D-flow MRI for quantifying flow and pulsatility in venous sinuses and large cerebral veins

Scientific Reports, Springer Nature 2025, Vol. 15, (1)

Westlund, Arvid; Wåhlin, Anders; Malm, Jan; et al.

Cerebral blood flow assessed with phase-contrast magnetic resonance imaging during blood pressure changes with noradrenaline and labetalol: a trial in healthy volunteers

Anesthesiology, Wolters Kluwer 2024, Vol. 140, (4) : 669-678

Birnefeld, Johan; Petersson, Karl; Wåhlin, Anders; et al.

Cerebral arterial stiffness is linked to white matter hyperintensities and perivascular spaces in older adults: a 4D flow MRI study

Journal of Cerebral Blood Flow and Metabolism, Sage Publications 2024, Vol. 44, (8) : 1343-1351

Björnfot, Cecilia; Eklund, Anders; Larsson, Jenny; et al.

Modeling CSF circulation and the glymphatic system during infusion using subject specific intracranial pressures and brain geometries

Fluids and Barriers of the CNS, BioMed Central (BMC) 2024, Vol. 21, (1)

Dreyer, Lars Willas; Eklund, Anders; Rognes, Marie E.; et al.

10-year mortality, causes of death and cardiovascular comorbidities in idiopathic normal pressure hydrocephalus

Journal of Neurology, Springer Nature 2024, Vol. 271 : 1311-1319

Eklund, Sanna; Israelsson, Hanna; Brunström, Mattias; et al.

Freezing of gait in idiopathic normal pressure hydrocephalus

Fluids and Barriers of the CNS, BioMed Central (BMC) 2024, Vol. 21, (1)

Kihlstedt, Carl-Johan; Malm, Jan; Fasano, Alfonso; et al.

CSF formation rate: a potential glymphatic flow parameter in hydrocephalus?

Fluids and Barriers of the CNS, BioMed Central (BMC) 2024, Vol. 21, (1)

Qvarlander, Sara; Sundström, Nina; Malm, Jan; et al.

Blood-brain barrier integrity is linked to cognitive function, but not to cerebral arterial pulsatility, among elderly

Scientific Reports, Springer Nature 2024, Vol. 14, (1)

Vikner, Tomas; Garpebring, Anders; Björnfot, Cecilia; et al.

Establishing the distribution of cerebrovascular resistance using computational fluid dynamics and 4D flow MRI

Scientific Reports, Springer Nature 2024, Vol. 14, (1)

Vikström, Axel; Holmlund, Petter; Holmgren, Madelene; et al.

Cerebral blood flow patterns in patients with low-flow carotid artery stenosis, a 4D-PCMRI assessment

Journal of Magnetic Resonance Imaging, John Wiley & Sons 2024, Vol. 60, (4) : 1521-1529

Zarrinkoob, Laleh; Myrnäs, Sanne; Wåhlin, Anders; et al.

Clinical features of idiopathic normal pressure hydrocephalus: critical review of objective findings

Movement Disorders Clinical Practice, John Wiley & Sons 2023, Vol. 10, (1) : 9-16

Bluett, Brent; Ash, Elissa; Farheen, Amtul; et al.

Vascular risk profiles for predicting outcome and long-term mortality in patients with idiopathic normal pressure hydrocephalus: comparison of clinical decision support tools

Journal of Neurosurgery, Journal of Neurosurgery Publishing Group (JNSPG) 2023, Vol. 138, (2) : 476-482

Eklund, Sanna A.; Israelsson, Hanna; Carlberg, Bo; et al.

Cerebral Microbleeds-Long-Term Outcome After Cerebrospinal Fluid Shunting in Idiopathic Normal Pressure Hydrocephalus

Neurosurgery, Wolters Kluwer 2023, Vol. 93, (2) : 300-308

Hansson, William; Johansson, Elias; Birgander, Richard; et al.

Placebo-controlled effectiveness of idiopathic normal pressure hydrocephalus shunting: a randomized pilot trial

Neurosurgery, Wolters Kluwer 2023, Vol. 92, (3) : 481-489

Luciano, Mark; Holubkov, Richard; Williams, Michael A.; et al.

Prediction of cerebral perfusion pressure during carotid surgery: A computational fluid dynamics approach

Clinical Biomechanics, Vol. 100

Holmgren, Madelene; Holmlund, Petter; Stoverud, Karen-Helene; et al.

5-year associations among cerebral arterial pulsatility, perivascular space dilation, and white matter lesions

Annals of Neurology, John Wiley & Sons 2022, Vol. 92, (5) : 871-881

Vikner, Tomas; Karalija, Nina; Eklund, Anders; et al.

4D flow MRI hemodynamic biomarkers for cerebrovascular diseases

Journal of Internal Medicine, John Wiley & Sons 2022, Vol. 291, (2) : 115-127

Wåhlin, Anders; Eklund, Anders; Malm, Jan

Assessing cerebral arterial pulse wave velocity using 4D flow MRI

Journal of Cerebral Blood Flow and Metabolism, Sage Publications 2021, Vol. 41, (10) : 2769-2777

Björnfot, Cecilia; Garpebring, Anders; Qvarlander, Sara; et al.

Risk factors for developing subdural hematoma: a registry-based study in 1457 patients with shunted idiopathic normal pressure hydrocephalus

Journal of Neurosurgery, American Association of Neurological Surgeons 2021, Vol. 134, (2) : 668-677

Gasslander, Johan; Sundström, Nina; Eklund, Anders; et al.

Middle cerebral artery pressure laterality in patients with symptomatic ICA stenosis

PLOS ONE, Public Library of Science 2021, Vol. 16, (1)

Holmgren, Madelene; Stoverud, Karen-Helene; Zarrinkoob, Laleh; et al.

Author Response: Posture-Dependent Collapse of the Optic Nerve Subarachnoid Space: A Combined MRI and Modeling Study

Investigative Ophthalmology and Visual Science, Vol. 62, (15)

Holmlund, Petter; Stoverud, Karen-Helene; Wahlin, Anders; et al.

Posture-dependent collapse of the optic nerve subarachnoid space: A combined MRI and modeling study

Investigative Ophthalmology and Visual Science, Association for Research in Vision and Ophthalmology 2021, Vol. 62, (4)

Holmlund, Petter; Stoverud, Karen-Helene; Wåhlin, Anders; et al.

Diagnosing carotid near-occlusion with phase-contrast MRI

American Journal of Neuroradiology, Vol. 42, (5) : 927-929

Johansson, Elias; Zarrinkoob, Laleh; Wåhlin, Anders; et al.

Falls and Fear of Falling in Shunted Idiopathic Normal Pressure Hydrocephalus: The Idiopathic Normal Pressure Hydrocephalus Comorbidity and Risk Factors Associated With Hydrocephalus Study

Neurosurgery, Oxford University Press 2021, Vol. 89, (1) : 122-128

Larsson, Jenny; Israelsson Larsen, Hanna; Eklund, Anders; et al.

Hemodynamic Disturbances in Posterior Circulation Stroke: 4D Flow Magnetic Resonance Imaging Added to Computed Tomography Angiography

Frontiers in Neuroscience, Frontiers Media S.A. 2021, Vol. 15

Malm, Jan; Birnefeld, Johan; Zarrinkoob, Laleh; et al.

Variability of Normal Pressure Hydrocephalus Imaging Biomarkers with Respect to Section Plane Angulation: How Wrong a Radiologist Can Be?

American Journal of Neuroradiology, American Society of Neuroradiology 2021, Vol. 42, (7) : 1201-1207

Ryska, P.; Slezak, O.; Eklund, A.; et al.

Cerebral arterial pulsatility is linked to hippocampal microvascular function and episodic memory in healthy older adults

Journal of Cerebral Blood Flow and Metabolism, Sage Publications 2021, Vol. 41, (7) : 1778-1790

Vikner, Tomas; Eklund, Anders; Karalija, Nina; et al.

Re: Wahlin et al.: Optic nerve length before and after spaceflight [REPLY]

Ophthalmology, Elsevier 2021, Vol. 128, (5) : E28-E28

Wahlin, Anders; Holmlund, Petter; Fellows, Abigail M.; et al.

Optic Nerve Length before and after Spaceflight

Ophthalmology, Elsevier 2021, Vol. 128, (2) : 309-316

Wåhlin, Anders; Holmlund, Petter; Fellows, Abigail M; et al.

Quantification and mapping of cerebral hemodynamics before and after carotid endarterectomy, using four-dimensional flow magnetic resonance imaging

Journal of Vascular Surgery, Elsevier 2021, Vol. 74, (3) : 910-920.e1

Zarrinkoob, Laleh; Wåhlin, Anders; Ambarki, Khalid; et al.

Cerebral arterial pulsatility is associated with features of small vessel disease in patients with acute stroke and TIA: a 4D flow MRI study

Journal of Neurology, Springer 2020, Vol. 267, (3) : 721-730

Birnefeld, Johan; Wåhlin, Anders; Eklund, Anders; et al.

Assessment of Cerebral Blood Flow Pulsatility and Cerebral Arterial Compliance With 4D Flow MRI

Journal of Magnetic Resonance Imaging, Wiley-Blackwell 2020, Vol. 51, (5) : 1516-1525

Holmgren, Madelene; Wåhlin, Anders; Dunås, Tora; et al.

Cerebrospinal Fluid Shunting Improves Long-Term Quality of Life in Idiopathic Normal Pressure Hydrocephalus

Neurosurgery, Oxford University Press 2020, Vol. 86, (4) : 574-582

Israelsson, Hanna; Eklund, Anders; Malm, Jan

Risk factors, comorbidities, quality of life, and complications after surgery in idiopathic normal pressure hydrocephalus: review of the INPH-CRasH study

Neurosurgical Focus, Rolling Meadows: American Association of Neurological Surgeons 2020, Vol. 49, (4)

Israelsson Larsen, Hanna; Larsson, Jenny; Eklund, Anders; et al.

Radiological markers of idiopathic normal pressure hydrocephalus: Relative comparison of their diagnostic performance

Journal of the Neurological Sciences, Elsevier 2020, Vol. 408

Ryska, Pavel; Slezak, Ondrej; Eklund, Anders; et al.

Characterizing pulsatility in distal cerebral arteries using 4D flow MRI

Journal of Cerebral Blood Flow and Metabolism, Sage Publications 2020, Vol. 40, (12) : 2429-2440

Vikner, Tomas; Nyberg, Lars; Holmgren, Madelene; et al.

Accuracy of blood flow assessment in cerebral arteries with 4D flow MRI: Evaluation with three segmentation methods

Journal of Magnetic Resonance Imaging, Vol. 50, (2) : 511-518

Dunås, Tora; Holmgren, Madelene; Wåhlin, Anders; et al.

Visa publikationer i DiVA

Forskningsprojekt

22 maj 2025 till 31 december 2035

Kan blodprover långt innan symtom avslöja vem som får normaltryckshydrocefalus?

1 januari 2014 till 31 december 2016

Fysiologiska studier av hur gravitation och hur dess hydrostatiska effekter påverkar hjärnans och ögats vätskesystem – med applikation att förstå astronauters synförändringar vid rymdresor

Publicerad: 11 maj, 2026

Ny metod mäter hjärnans ”städsystem”

Publicerad: 18 sep, 2025

Kirurgiskt ingrepp hjälp för vätskeflöde i hjärnan

Publicerad: 15 aug, 2022

Tre projekt får stöd av Hjärnfonden

Publicerad: 04 sep, 2019

Strategiska miljoner till forskning om hjärnflöden