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Umeå universitet
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Huvudmenyn dold.

Jurgen Schleucher

Mitt forskningsområde är biomolekylär funktion från molekylär till global skala.

Vetenskaplig meritering: Docent

Kontakt

E-post
jurgen.schleucher@umu.se
Telefon
070-549 46 64

Verksam vid

Anknytning
Professor vid Institutionen för medicinsk kemi och biofysik
Plats
KB. H6, Campus, Umeå Umeå universitet, 901 87 Umeå

Proteiner och nukleinsyror utför kroppens funktioner. Vi undersöker deras strukturer och dynamik, för att förstå hur de fungerar inom hälsa och sjukdom. Bilden visar epsilon-RNA av hepatit B-viruset, den innehåller nukleotider som är mobila (färgade) men bevarade, vilket indikerar att struktur och molekylär rörlighet är optimerade i evolutionen.

Stabila isotoper förekommer överallt i naturen. Vi använder dem som spårämnen av metabolisk reglering, från skalan av biokemiska vägar till den globala biosfären. Vilka enzymer reglerar vägar i ostörda organismer? Hur kommer den globala fotosyntesen att reagera på klimatförändringarna?

NMR:s metodutveckling är ett centralt komplement till bägge forskningsområden.

A model of photosynthetic CO2 assimilation in C3 leaves accounting for respiration and energy recycling by the plastidial oxidative pentose phosphate pathway
New Phytologist, John Wiley & Sons 2023, Vol. 239, (2) : 518-532
Wieloch, Thomas; Augusti, Angela; Schleucher, Jürgen
Organochemical characterization of peat reveals decomposition of specific hemicellulose structures as the main cause of organic matter loss in the acrotelm
Environmental Science and Technology, American Chemical Society (ACS) 2022, Vol. 56, (23) : 17410-17419
Serk, Henrik; Nilsson, Mats B.; Figueira, Joao; et al.
Soil phosphorus forms show only minor changes across a 5000-year-old boreal wildfire chronosequence
Biogeochemistry, Springer 2022, Vol. 159 : 15-32
Vincent, Andrea G.; Schleucher, Jürgen; Giesler, Reiner; et al.
Anaplerotic flux into the Calvin–Benson cycle: hydrogen isotope evidence for in vivo occurrence in C 3 metabolism
New Phytologist, John Wiley & Sons 2022, Vol. 234, (2) : 405-411
Wieloch, Thomas; Augusti, Angela; Schleucher, Jürgen
Metabolism is a major driver of hydrogen isotope fractionation recorded in tree‐ring glucose of Pinus nigra
New Phytologist, John Wiley & Sons 2022, Vol. 234, (2) : 449-461
Wieloch, Thomas; Grabner, Michael; Augusti, Angela; et al.
Intramolecular carbon isotope signals reflect metabolite allocation in plants
Journal of Experimental Botany, Oxford University Press 2022, Vol. 73, (8) : 2558-2575
Wieloch, Thomas; Sharkey, Thomas David; Werner, Roland Anton; et al.
Global CO2 fertilization of Sphagnum peat mosses via suppression of photorespiration during the twentieth century
Scientific Reports, Nature Publishing Group 2021, Vol. 11, (1)
Serk, Henrik; Nilsson, Mats B.; Bohlin, Elisabet; et al.
CO2 fertilization of Sphagnum peat mosses is modulated by water table level and other environmental factors
Plant, Cell and Environment, John Wiley & Sons 2021, Vol. 44, (6) : 1756-1768
Serk, Henrik; Nilsson, Mats B.; Figueira, Joao; et al.
Integrating the evidence for a terrestrial carbon sink caused by increasing atmospheric CO2
New Phytologist, John Wiley & Sons 2021, Vol. 229, (5) : 2413-2445
Walker, Anthony P.; De Kauwe, Martin G.; Bastos, Ana; et al.
Metabolism is the major driver of hydrogen isotope fractionation recorded in tree-ring glucose of Pinus nigra
Wieloch, Thomas; Grabner, Michael; Augusti, Angela; et al.
Carbon flux around leaf-cytosolic glyceraldehyde-3-phosphate dehydrogenase introduces a 13C signal in plant glucose
Journal of Experimental Botany, Oxford University Press 2021, Vol. 72, (20) : 7136-7144
Wieloch, Thomas; Werner, Roland Anton; Schleucher, Jürgen
Nitrogen dynamics of decomposing Scots pine needle litter depends on colonizing fungal species
FEMS Microbiology Ecology, Oxford University Press 2019, Vol. 95, (6)
Baskaran, Preetisri; Ekblad, Alf; Soucémarianadin, Laure N.; et al.
Microbial utilization of simple carbon substrates in boreal peat soils at low temperatures
Soil Biology and Biochemistry, Elsevier 2019, Vol. 135 : 438-448
Segura, Javier H.; Nilsson, Mats B.; Schleucher, Jürgen; et al.
Boreal tree species affect soil organic matter composition and saprotrophic mineralization rates
Plant and Soil, Springer 2019, Vol. 441, (1-2) : 173-190
Segura, Javier H.; Nilsson, Mats B.; Sparrman, Tobias; et al.
2H-fractionations during the biosynthesis of carbohydrates and lipids imprint a metabolic signal on the δ2H values of plant organic compounds
New Phytologist, Wiley-Blackwell 2018, Vol. 218, (2) : 479-491
Cormier, Marc-André; Werner, Roland A.; Sauer, Peter E.; et al.
Intramolecular stable isotope variation: Consequences for conventional isotope measurements and elucidation of new ecophysiological signals
Geophysical Research Abstracts
Schleucher, Jürgen; Wieloch, Thomas; Serk, Henrik; et al.
Tree-ring cellulose exhibits several interannual 13C signals on the intramolecular level
Geophysical Research Abstracts
Wieloch, Thomas; Ehlers, Ina; Yu, Jun; et al.
Intramolecular 13C analysis of tree rings provides multiple plant ecophysiology signals covering decades
Scientific Reports, Vol. 8
Wieloch, Thomas; Ehlers, Ina; Yu, Jun; et al.
Microbial mineralization of cellulose in frozen soils
Nature Communications, London: Nature Publishing Group 2017, Vol. 8, (1)
Segura, Javier H.; Nilsson, Mats B.; Haei, Mahsa; et al.
Two dimensional NMR spectroscopy for molecular characterization of soil organic matter: Application to boreal soils and litter
Organic Geochemistry, Vol. 113 : 184-195
Soucemarianadin, Laure N.; Erhagen, Björn; Nilsson, Mats B.; et al.
The effect of temperature and substrate quality on the carbon use efficiency of saprotrophic decomposition
Plant and Soil, Vol. 414, (1) : 113-125
Öquist, Mats G.; Erhagen, Björn; Haei, Mahsa; et al.
Detecting plant-climate interactions over decades-millennia using NMR isotopomer analysis
Geophysical Research Abstracts
Ehlers, Ina; Augusti, Angela; Köhler, Iris; et al.
Detecting long-term metabolic shifts using isotopomers: CO2-driven suppression of photorespiration in C-3 plants over the 20th century
Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, (51) : 15585-15590
Ehlers, Ina; Augusti, Angela; Betson, Tatiana R.; et al.
Compound-specific carbon, nitrogen, and hydrogen isotope analysis of N-nitrosodimethylamine in aqueous solutions
Analytical Chemistry, Vol. 87, (5) : 2916-2924
Spahr, Stephanie; Bolotin, Jakov; Schleucher, Jürgen; et al.
Interaction Studies of the Human and Arabidopsis thaliana Med25-ACID Proteins with the Herpes Simplex Virus VP16-and Plant-Specific Dreb2a Transcription Factors
PLOS ONE, Vol. 9, (5) : e98575-
Aguilar, Ximena; Blomberg, Jeanette; Brännström, Kristoffer; et al.
Elucidating Turnover Pathways of Bioactive Small Molecules by Isotopomer Analysis: The Persistent Organic Pollutant DDT
PLOS ONE, PLoS ONE 2014, Vol. 9, (10) : e110648-
Ehlers, Ina; Betson, Tatiana R.; Vetter, Walter; et al.
Enhanced photosynthetic efficiency in trees world-wide by rising atmospheric CO2 levels
EGU General Assembly 2014
Ehlers, Ina; Wieloch, Thomas; Groenendijk, Peter; et al.
Effect of Trees on Forms of Soil Phosphorus in an Agroforestry Parkland in Burkina Faso
Vestergren, Johan; Ouattara, Korodjouma; Schleucher, Jurgen; et al.
Site-specific C-13 content by quantitative isotopic C-13 nuclear magnetic resonance spectrometry: a pilot inter-laboratory study
Analytica Chimica Acta, Vol. 788 : 108-113
Chaintreau, Alain; Fieber, Wolfgang; Sommer, Horst; et al.
A Complex of Equine Lysozyme and Oleic Acid with Bactericidal Activity against Streptococcus pneumoniae
PLOS ONE, Public Library of Science 2013, Vol. 8, (11) : Article Number: UNSP e80649-
Clementi, Emily A.; Wilhelm, Kristina R.; Schleucher, Juergen; et al.
Temperature response of litter and soil organic matter decomposition is determined by chemical composition of organic material
Global Change Biology, Wiley-Blackwell 2013, Vol. 19, (12) : 3858-3871
Erhagen, Björn; Öquist, Mats; Sparrman, Tobias; et al.
Two-Dimensional P-31,H-1 NMR Spectroscopic Profiling of Phospholipids in Cheese and Fish
Journal of Agricultural and Food Chemistry, Vol. 61, (29) : 7061-7069
Kaffarnik, Stefanie; Ehlers, Ina; Gröbner, Gerhard; et al.
NMR for LifeA national research infrastructure: a new NMR infrastructure provides access to world-class instruments for users from a wide range of research fields.
Kemivärlden biotech / kemisk tidskrift, Journal of Chemistry and Biotechnology 2013, (3) : 35-37
Schleucher, Jürgen; Gröbner, Gerhard; Karlsson, Göran
Novel Approaches for Identifying Phosphorus Species in Terrestrial and Aquatic Ecosystems with P-31 NMR
Biophysical Journal, Vol. 104, (2) : 501A-502A
Vestergren, Johan E.; Vincent, Andrea G.; Persson, Per; et al.
Phosphorus in forest soils: disentangling the chemistry of an essential nutrient
Forest facts, SLU 2013, (4)
Vincent, Andrea G; Ilstedt, Ulrik; Vestergren, Johan; et al.
Soil organic phosphorus transformations in a boreal forest chronosequence
Plant and Soil, Dordrecht: Springer 2013, Vol. 367, (1-2) : 149-162
Vincent, Andrea G.; Vestergren, Johan; Gröbner, Gerhard; et al.
Solution structure, copper binding and backbone dynamics of recombinant Ber e 1: the major allergen from brazil nut
PLOS ONE, San Francisco: Public Library of Science 2012, Vol. 7, (10) : e46435-
Rundqvist, Louise; Tengel, Tobias; Zdunek, Janusz; et al.
High resolution characterization of organic phosphorus in soil extracts using 2D 1H-31P NMR correlation spectroscopy
Environmental Science and Technology, American Chemical Society (ACS) 2012, Vol. 46, (7) : 3950-3956
Vestergren, Johan; Vincent, Andrea G; Jansson, Mats; et al.
Changes in organic phosphorus composition in boreal forest humus soils: the role of iron and aluminium
Biogeochemistry, Springer 2012, Vol. 108, (1-3) : 485-499
Vincent, Andrea G; Schleucher, Jürgen; Gröbner, Gerhard; et al.
Both catabolic and anabolic heterotrophic microbial activity proceed in frozen soils
Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, (49) : 21046-21051
Drotz, Stina Harrysson; Sparrman, Tobias; Nilsson, Mats B; et al.
Effects of soil organic matter composition on unfrozen water content and heterotrophic CO2 production of frozen soils
Geochimica et Cosmochimica Acta, Elsevier Ltd 2010, Vol. 74, (8) : 2281-90
Drotz, Stina Harrysson; Sparrman, Tobias; Schleucher, Jürgen; et al.
Improved rapid authentication of vanillin using δ13C and δ2H values
European Food Research and Technology, Vol. 231, (6) : 933-941
Greule, Markus; Tumino, Luisa Dana; Kronewald, Tatjana; et al.
The interaction of equine lysozyme: oleic acid complexes with lipid membranes suggests a cargo off-loading mechanism
Journal of Molecular Biology, Elsevier 2010, Vol. 398, (2) : 351-361
Nielsen, Søren B; Wilhelm, Kristina; Vad, Brian; et al.
Biochemical and functional characterization of Helicobacter pylori vesicles
Molecular Microbiology, Wiley 2010, Vol. 77, (6) : 1539-1555
Olofsson, Annelie; Vallström, Anna; Petzold, Katja; et al.
TOCSY in ROESY and ROESY in TOCSY
Multidimensional NMR methods for the solution state, John Wiley & Sons 2010 : 259-276
Schleucher, Jürgen; Quant, Jens; Glaser, Steffen; et al.
Lipoprotein complex of equine lysozyme with oleic acid (ELOA) interactions with the plasma membrane of live cells
Langmuir, American Chemical Society 2010, Vol. 26, (18) : 14782-14787
Vukojevic, Vladana; Bowen, Alice M; Wilhelm, Kristina; et al.
Contributions of matric and osmotic potentials to the unfrozen water content of frozen soils
Geoderma, Elsevier B.V. 2009, Vol. 148, (3-4) : 392-8
Harrysson Drotz, Stina; Tilston, Emma L; Sparrman, Tobias; et al.
Semiconstant-Time P,H-COSY NMR: Analysis of Complex Mixtures of Phospholipids Originating from Helicobacter pylori
Journal of the American Chemical Society, ACS Publications ASAP 2009, Vol. 131, (40) : 14150-1
Petzold, Katja; Olofsson, Annelie; Arnqvist, Anna; et al.
EASY ROESY: reliable cross-peak integration in adiabatic symmetrized ROESY
Chemistry - A European Journal, Vol. 15, (3) : 585-588
Thiele, Christina Marie; Petzold, Katja; Schleucher, Jürgen
Protein oligomerization induced by oleic acid at the solidliquid interface: equine lysozyme cytotoxic complexes
The FEBS Journal, Vol. 276, (15) : 3975-3989
Wilhelm, Kristina; Darinskas, A; Noppe, W; et al.
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