Michael Druzin

Vetenskaplig meritering: Docent

Pedagogisk meritering: Meriterad lärare

Kontakt

michael.druzin@umu.se

090-786 54 96

Verksam som

Universitetslektor vid Institutionen för medicinsk och translationell biologi Enhet: Grupp Michael Druzin

hus H, Johan Bures väg 12, Biologihuset Umeå universitet, 901 87 Umeå

Vi studerar synaptisk signalering i hypotalamiska nervkretsar med hjälp av patch-clamp-elektrofysiologi, avancerad mikroskopi och molekylärbiologi för att förstå de mekanismer som reglerar hjärnans funktion i hälsa och sjukdom.

O-GlcNAc transferase couples nutrient availability to synaptic plasticity in paraventricular neurons to regulate satiety

Journal of Biological Chemistry, Elsevier 2026, Vol. 302, (2)

Pérez-del-Pozo, Mario; Bhattacharjee, Manish; Tripathi, Anushree; et al.

Presynaptic chloride-dependent regulation of spontaneous glutamate release in the rat medial preoptic nucleus

Frontiers in Cellular Neuroscience, Frontiers Media S.A. 2026, Vol. 20

Pérez-del-Pozo, Mario; Kuznetsova, Tatiana; Johansson, Staffan; et al.

Shunting effect of synaptic channels located on presynaptic terminal

Advances in neural computation, machine learning, and cognitive research VI: Selected papers from the XXIV International Conference on Neuroinformatics, October 17-21, 2022, Moscow, Russia, Springer Science and Business Media Deutschland GmbH 2023 : 223-230

Kotikova, Marie R.; Druzin, Michael; Chizhov, Anton V.

Heparan sulfates regulate axonal excitability and context generalization through CA2+/Calmodulin-dependent protein kinase II

Cells, MDPI 2023, Vol. 12, (5)

Song, Inseon; Kuznetsova, Tatiana; Baidoe-Ansah, David; et al.

Medroxyprogesterone acetate positively modulates specific GABAA-receptor subtypes - affecting memory and cognition

Psychoneuroendocrinology, Elsevier 2022, Vol. 141

Das, Roshni; Ragagnin, Gianna; Sjöstedt, Jessica; et al.

Choosing the optimal rat stock as a model for research into pharmacological correction of male sexual dysfunction

Sovremennye Tehnologii v Medicine, Privolzhsky Research Medical University 2021, Vol. 13, (6) : 36-41

Zhuravleva, Z.D.; Titova, N.A.; Mukhina, I.V.; et al.

Effects of Glycine Receptors of the Medial Preoptic Nucleus on Sexual Behavior of Male Wistar Rats

Bulletin of experimental biology and medicine, Springer 2020, Vol. 169, (3) : 299-301

Zhuravleva, Z. D.; Mogutina, M. A.; Mukhina, I. V.; et al.

Contribution of Resting Conductance, GABA(A)-Receptor Mediated Miniature Synaptic Currents and Neurosteroid to Chloride Homeostasis in Central Neurons

eNeuro, Vol. 4, (2)

Yelhekar, Tushar D.; Druzin, Michael; Johansson, Staffan

Preoptic glycine receptors: possible mediators of neuron-glial interaction affecting social behavior in male rats

Glia, John Wiley & Sons 2017, Vol. 65 : E298-E299

Zhuravleva, Z.; Titova, N.; Mukhina, I.; et al.

2-aminoethyl diphenylborinate blocks GABAA-receptor-mediated currents in rat medial preoptic neurons

Opera Medica Et Physiologica, Nizhni Novgorod: Lobachevsky State University of Nizhny Novgorod 2016, Vol. 2, (1) : 63-68

Druzin, Michael; Johansson, Staffan

Commentary: Chloride Regulation: a Dynamic Equilibrium Crucial for Synaptic Inhibition

Frontiers in Cellular Neuroscience, Vol. 10

Johansson, Staffan; Yelhekar, Tushar D.; Druzin, Michael

Mechanism of hypothalamus glycine receptor involvement in regulation of sexual behavior

Acta Physiologica, Vol. 217 : 95-95

Lebedeva, Albina; Zhuravleva, Zoya; Denisov, Pavel; et al.

How to Properly Measure a Current-Voltage Relation? -Interpolation vs. Ramp Methods Applied to Studies of GABA(A) Receptors

Frontiers in Cellular Neuroscience, Vol. 10

Yelhekar, Tushar D.; Druzin, Michael; Karlsson, Urban; et al.

Setting neuronal chloride gradient: a new role for extracellular matrix

Acta Physiologica, Vol. 215 : 45-45

Druzin, Michael

Regulation of neuronal chloride homeostasis: a new role for extracellular matrix

Opera Medica et Physiologica, Lobachevsky State University of Nizhny Novgorod 2015, Vol. 1, (S 1) : 10-10

Druzin, Michael

The effect of glycine microinjections in the medial preoptic area of the hypothalamus on the sexual behavior of male rats

Neurochemical Journal, Vol. 9, (2) : 141-145

Zhuravleva, Z. D.; Lebedeva, A. V.; Volnova, A. B.; et al.

The role of the medial preoptic area glycinergic system in the social types of behavior regulation

Opera Medica et Physiologica, Vol. 1 : 21-22

Zhuravleva, Z.D.; Denisov, P.A.; Urazov, M.D.; et al.

Firing clamp: a novel method for single-trial estimation of excitatory and inhibitory synaptic neuronal conductances.

Frontiers in Cellular Neuroscience, Vol. 8, (86) : 86-

Chizhov, Anton V; Malinina, Evgenia; Druzin, Michael; et al.

Hypoxia on a chip: a novel approach for patch-clamp studies in a microfluidic system with full oxygen control

World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China, Springer Berlin/Heidelberg 2013 : 313-316

Alrifaiy, Ahmed; Bitaraf, Nazanin; Druzin, Michael; et al.

Mechanism of estradiol-induced block of voltage-gated K+ currents in rat medial preoptic neurons.

PLOS ONE, San Francisco: Public Library of Science 2011, Vol. 6, (5) : e20213-

Druzin, Michael; Malinina, Evgenya; Grimsholm, Ola; et al.

Cl⁻ concentration changes and desensitization of GABA_A and glycine receptors

The Journal of General Physiology, Vol. 138, (6) : 609-626

Karlsson, Urban; Druzin, Michael; Johansson, Staffan

Spontaneous ryanodine-receptor-dependent Ca2+-activated K+ currents and hyperpolarizations in rat medial preoptic neurons

Journal of Neurophysiology, Vol. 103, (5) : 2900-2911

Klement, Göran; Druzin, Michael; Haage, David; et al.

Differential control of spontaneous and evoked GABA release by presynaptic L-type Ca(2+) channels in the rat medial preoptic nucleus

Journal of Neurophysiology, Vol. 104, (1) : 200-209

Malinina, Evgenya; Druzin, Michael; Johansson, Staffan

Development of a multifunctional microfluidic system for studies of nerve cell activity during hypoxic and anoxic conditions

International Federation for Medical and Biological Engineering Proceedings; 25 : 176-179

Bitaraf, Nazanin; Ahmed, Ahmed; Druzin, Michael; et al.

Short-term plasticity in excitatory synapses of the rat medial preoptic nucleus.

Brain Research, Vol. 1110, (1) : 128-35

Malinina, Evgenya; Druzin, Michael; Johansson, Staffan

Fast neurotransmission in the rat medial preoptic nucleus.

Brain Research, Vol. 1040, (1-2) : 157-68

Malinina, Evgenya; Druzin, Michael; Johansson, Staffan

Bicuculline free base blocks voltage-activated K+ currents in rat medial preoptic neurons.

Neuropharmacology, Vol. 46, (2) : 285-95

Druzin, Michael; Haage, David; Johansson, Staffan

Dual and opposing roles of presynaptic Ca2+ influx for spontaneous GABA release from rat medial preoptic nerve terminals.

Journal of Physiology, Vol. 542, (Pt 1) : 131-46

Druzin, Michael; Haage, David; Malinina, Evgenya; et al.

Allopregnanolone modulates spontaneous GABA release via presynaptic Cl- permeability in rat preoptic nerve terminals

Brain Research, Elsevier 2002, Vol. 958, (2) : 405-413

Haage, David; Druzin, Michael; Johansson, Staffan

O-GlcNAc transferase regulates GABAergic synapse organization and receptor composition

Bhattacharjee, Manish; Han, Linkun; Elenska, Petya; et al.

Differential control of spontaneous and evoked GABA release by presynaptic L-type Ca²⁺ channels in the rat medial preoptic nucleus

Malinina, Evgenya; Druzin, Michael; Johansson, Staffan

Extracellular Matrix Regulates Neuronal Chloride Concentration via K⁺-Cl^--cotransporter 2

Yelhekar, Tushar; Kuznetsova, Tatiana; Malinina, Evgenya; et al.

Visa publikationer i DiVA

Forskargrupper

Forskningsledare

Michael Druzin

Gruppmedlem

Staffan Johansson

Jag undervisar studenter på läkar-, tandläkar- och kognitionsvetenskapsprogrammen i neurovetenskap och fysiologi.

Jag är också kursansvarig för fyra kurser vid Umeå universitet.

Läkarprogrammet:

Organens struktur och funktion (OSoF, 46,5 hp)

Kandidatprogrammet i kognitionsvetenskap:

Handling (9 hp)
NeuroKogVet I (9 hp)
NeuroKogVet II (9 hp)