Anders Widmark

Professor, senior vid Institutionen för strålningsvetenskaper Enhet: Onkologi

27C, Målpunkt QC11, NUS, NUS Umeå universitet, 901 87 Umeå

I min forskning vill jag föbättra behandling av prostatacancer. SPCG-7 studien visar att tillägget av strålbehandling vid lokal högrisktumör halverar risken att avlida i prostatacancer.

Senaste publikationer

2019

Erectile Dysfunction and Absorbed Dose to Penile Base Structures in a Randomized Trial Comparing Ultrahypofractionated and Conventionally Fractionated Radiotherapy for Prostate Cancer

International Journal of Radiation Oncology, Biology, Physics, Elsevier 2019, Vol. 105, (1) : S133-S134

Rasmusson, E.; Gunnlaugsson, A.; Wieslander, E.; et al.

2019

Gene expression profiles define molecular subtypes of prostate cancer bone metastases with different outcomes and morphology traceable back to the primary tumor

Molecular Oncology, John Wiley & Sons 2019, Vol. 13, (8) : 1763-1777

Thysell, Elin; Vidman, Linda; Bovinder Ylitalo, Erik; et al.

2019

Radiation dosimetry of [Ga-68]PSMA-11 in low-risk prostate cancer patients

EJNMMI Physics, Springer 2019, Vol. 6

Sandgren, Kristina; Johansson, Lennart; Axelsson, Jan; et al.

2019

Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial

The Lancet, Elsevier 2019, Vol. 394, (10196) : 385-395

Widmark, Anders; Gunnlaugsson, Adalsteinn; Beckman, Lars; et al.

2018

Bone Cell Activity in Clinical Prostate Cancer Bone Metastasis and Its Inverse Relation to Tumor Cell Androgen Receptor Activity

International Journal of Molecular Sciences, MDPI 2018, Vol. 19, (4)

Nordstrand, Annika; Bovinder Ylitalo, Erik; Thysell, Elin; et al.

2018

Bone remodeling in relation to androgen receptor activity in prostate cancer bone metastases

Cancer Research, American Association for Cancer Research 2018, Vol. 78, (16) : 50-50

Bovinder Ylitalo, Erik; Nordstrand, Annika; Thysell, Elin; et al.

2018

Clinically relevant molecular subgroups of prostate cancer bone metastases

Cancer Research, American Association for Cancer Research 2018, Vol. 78, (16) : 123-123

Thysell, Elin; Bovinder Ylitalo, Erik; Jernberg, Emma; et al.

2018

Histology correlation of in vivo [68Ga]PSMA-PET/MRI data of the prostate

Radiotherapy and Oncology, Elsevier 2018, Vol. 127 : S541-S541

Sandgren, Kristina; Jonsson, Joakim; Nyholm, Tufve; et al.

2018

Osteoblast-derived factors promote metastatic potential in human prostate cancer cells, in part via non-canonical transforming growth factor β (TGFβ) signaling

The Prostate, Vol. 78, (6) : 446-456

Karlsson, Terese; Sundar, Reshma; Widmark, Anders; et al.

2018

Phase 3 Assessment of the Automated Bone Scan Index as a Prognostic Imaging Biomarker of Overall Survival in Men With Metastatic Castration-Resistant Prostate Cancer: A Secondary Analysis of a Randomized Clinical Trial

JAMA Oncology, Vol. 4, (7) : 944-951

Armstrong, Andrew J.; Anand, Aseem; Edenbrandt, Lars; et al.

2018

Platelets harbor prostate cancer biomarkers and the ability to predict therapeutic response to abiraterone in castration resistant patients

The Prostate, Wiley-Blackwell 2018, Vol. 78, (1) : 48-53

Tjon-Kon-Fat, Lee-Ann; Lundholm, Marie; Schröder, Mona; et al.

2018

Prostate Cancer Death After Radiotherapy or Radical Prostatectomy: A Nationwide Population-based Observational Study

European Urology, Elsevier 2018, Vol. 73, (4) : 502-511

Robinson, David; Garmo, Hans; Lissbrant, Ingela Franck; et al.

2018

The proteome of prostate cancer bone metastases

Cancer Research, American Association for Cancer Research 2018, Vol. 78, (16) : 91-92

Iglesias-Gato, Diego; Thysell, Elin; Crnalic, Sead; et al.

2018

The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications

Clinical Cancer Research, American Association for Cancer Research 2018, Vol. 24, (21) : 5433-5444

Iglesias-Gato, Diego; Thysell, Elin; Tyanova, Stefka; et al.

2018

Three-year Safety of Radium-223 Dichloride in Patients with Castration-resistant Prostate Cancer and Symptomatic Bone Metastases from Phase 3 Randomized Alpharadin in Symptomatic Prostate Cancer Trial

European Urology, Elsevier 2018, Vol. 73, (3) : 427-435

Parker, Christopher C.; Coleman, Robert E.; Sartor, Oliver; et al.

2018

Ultrahypofractionation for prostate cancer: Outcome from the Scandinavian phase 3 HYPO-RT-PC trial

Radiotherapy and Oncology, Elsevier 2018, Vol. 127 : S314-S314

Widmark, Anders; Gunnlaugsson, A.; Beckman, Lars; et al.

2017

Cabazitaxel followed by androgen deprivation therapy (ADT) significantly improves time to progression in patients with newly diagnosed metastatic hormone sensitive prostate cancer (mHSPC): A randomized, open label, phase III, multicenter trial

Annals of Oncology, OXFORD UNIV PRESS 2017, Vol. 28

Andren, O.; Widmark, Anders; Falt, A.; et al.

2017

Hematologic Safety of Radium-223 Dichloride: Baseline Prognostic Factors Associated With Myelosuppression in the ALSYMPCA Trial

Clinical Genitourinary Cancer, CIG MEDIA GROUP, LP 2017, Vol. 15, (1) : 42-52

Vogelzang, Nicholas J.; Coleman, Robert E.; Michalski, Jeff M.; et al.

2017

High Levels of the AR-V7 Splice Variant and Co-Amplification of the Golgi Protein Coding YIPF6 in AR Amplified Prostate Cancer Bone Metastases

The Prostate, Wiley-Blackwell Publishing Inc. 2017, Vol. 77, (6) : 625-638

Djusberg, Erik; Jernberg, Emma; Thysell, Elin; et al.

2017

Inhibition of the insulin-like growth factor-1 receptor potentiates acute effects of castration in a rat model for prostate cancer growth in bone

Clinical and Experimental Metastasis, Springer 2017, Vol. 34, (3-4) : 261-271

Nordstrand, Annika; Halin Bergström, Sofia; Thysell, Elin; et al.

2017

Metastatic spinal cord compression as the first sign of malignancy: Outcome after surgery in 69 patients

Acta Orthopaedica, Taylor & Francis 2017, Vol. 88, (4) : 457-462

Wänman, Johan; Grabowski, Pawel; Nyström, Helena; et al.

2017

Prostate Cancer Radiation Therapy and Risk of Thromboembolic Events

International Journal of Radiation Oncology, Biology, Physics, Elsevier 2017, Vol. 97, (5) : 1026-1031

Bosco, Cecilia; Garmo, Hans; Adolfsson, Jan; et al.

2017

Subgroups of castration-resistant prostate cancer bone metastases defined through an inverse relationship between androgen receptor activity and immune response

European Urology, Vol. 71, (5) : 776-787

Bovinder Ylitalo, Erik; Thysell, Elin; Jernberg, Emma; et al.

2017

Survival Among Men at High Risk of Disseminated Prostate Cancer Receiving Initial Locally Directed Radical Treatment or Initial Androgen Deprivation Therapy

European Urology, Elsevier 2017, Vol. 72, (3) : 345-351

Sooriakumaran, Prasanna; Nyberg, Tommy; Akre, Olof; et al.

2016

ATLAS: A phase 3 trial evaluating the efficacy of apalutamide (ARN-509) in patients with high-risk localized or locally advanced prostate cancer receiving primary radiation therapy

Annals of Oncology, Vol. 27

Bossi, A.; Dearnaley, D.; McKenzie, M.; et al.

2016

Extratumoral Heme Oxygenase-1 (HO-1) Expressing Macrophages Likely Promote Primary and Metastatic Prostate Tumor Growth

PLoS ONE, Vol. 11, (6)

Halin Bergström, Sofia; Nilsson, Maria; Adamo, Hanibal; et al.

2016

Extreme Hypofractionation versus Conventionally Fractionated Radiotherapy for Intermediate Risk Prostate Cancer: Early Toxicity Results from the Scandinavian Randomized Phase III Trial "HYPO-RT-PC"

International Journal of Radiation Oncology, Biology, Physics, Elsevier 2016, Vol. 96, (5) : 938-939

Widmark, Anders; Gunnlaugsson, A.; Beckman, L.; et al.

2016

Long-term adverse effects after curative radiotherapy and radical prostatectomy: population-based nationwide register study

Scandinavian journal of urology, Vol. 50, (5) : 338-345

Fridriksson, Jón O.; Folkvaljon, Yasin; Nilsson, Per; et al.

2016

Population-based study of long-term functional outcomes after prostate cancer treatment

BJU International, John Wiley & Sons 2016, Vol. 117, (6B) : E36-E45

Carlsson, Sigrid; Drevin, Linda; Loeb, Stacy; et al.

2016

Ten- and 15-yr Prostate Cancer-specific Mortality in Patients with Nonmetastatic Locally Advanced or Aggressive Intermediate Prostate Cancer, Randomized to Lifelong Endocrine Treatment Alone or Combined with Radiotherapy: Final Results of The Scandinavian Prostate Cancer Group-7

European Urology, Vol. 70, (4) : 684-691

Fossa, Sophie D.; Wiklund, Fredrik; Klepp, Olbjorn; et al.

2016

The Proteome of Primary Prostate Cancer

European Urology, Vol. 69, (5) : 942-952

Iglesias-Gato, Diego; Wikström, Pernilla; Tyanova, Stefka; et al.

2016

Tumor Cell-Derived Exosomes from the Prostate Cancer Cell Line TRAMP-C1 Impair Osteoclast Formation and Differentiation

PLoS ONE, Vol. 11, (11)

Karlsson, Terese; Lundholm, Marie; Widmark, Anders; et al.

2015

External-beam radiation therapy (EBRT) use and safety with Radium-223 dichloride (Ra) in patients (pts) with castration-resistant prostate cancer (CRPC) and symptomatic bone metastases (mets) from the ALSYMPCA trial

Oncology Research and Treatment, Vol. 38 : 82-82

Stroelin, P.; O'Sullivan, J.; Sartor, O.; et al.

2015

Lag time to adverse events after radical prostatectomy and curative radiotherapy

Journal of Clinical Oncology, Vol. 33, (7 S)

Thellenberg-Karlsson, Camilla; Fridriksson, Jon; Folkvaljon, Yasin; et al.

2015

Patient-reported gastrointestinal and genitourinary toxicity after prostate cancer treatment: A comparison between radiotherapy including pelvic nodes and prostate-only radiotherapy

Journal of Clinical Oncology, Vol. 33, (7 S)

Fransson, Per; Olofsson, Sebastian; Widmark, Anders; et al.

2015

Prospective assessment of urinary, gastrointestinal and sexual symptoms before, during and after image-guided volumetric modulated arc therapy for prostate cancer

Scandinavian journal of urology, Taylor & Francis 2015, Vol. 49, (1) : 58-69

Sveistrup, Joen; Widmark, Anders; Fransson, Per; et al.

2014

Change in prostate volume during extreme hypo-fractionation analysed with MRI

Radiation Oncology, Vol. 9 : 22-

Gunnlaugsson, Adalsteinn; Kjellen, Elisabeth; Hagberg, Oskar; et al.

2014

Effect of radium-223 dichloride on symptomatic skeletal events in patients with castration-resistant prostate cancer and bone metastases: results from a phase 3, double-blind, randomised trial

The Lancet Oncology, Vol. 15, (7) : 738-746

Sartor, Oliver; Coleman, Robert; Nilsson, Sten; et al.

2014

EXTERNAL-BEAM RADIATION THERAPY (EBRT) USE AND SAFETY WITH RADIUM-223 DICHLORIDE (RA) IN PATIENTS (PTS) WITH CASTRATION-RESISTANT PROSTATE CANCER (CRPC) AND SYMPTOMATIC BONE METASTASES (METS) FROM THE ALSYMPCATRIAL

Annals of Oncology, Vol. 25, (suppl 4) : 768P-

O'Sullivan, J. M.; Sartor, O.; Parker, C.; et al.

2014

Prostate Tumor-Derived Exosomes Down-Regulate NKG2D Expression on Natural Killer Cells and CD8(+) T Cells: Mechanism of Immune Evasion

PLoS ONE, Vol. 9, (9) : e108925-

Lundholm, Marie; Schröder, Mona; Nagaeva, Olga; et al.

2014

Svensk medicinsk forskning behöver inte mer styrning

Läkartidningen, Vol. 111, (22-23) : 980-981

Andersén, Peter; Bäckström, Torbjörn; Dahlquist, Gisela; et al.

2014

Ten-and 15-year prostate cancer-specific survival in patients with nonmetastatic high-risk prostate cancer randomized to lifelong hormone treatment alone or combined with radiotherapy (SPCG VII)

Journal of Clinical Oncology, Vol. 32, (4)

Fossa, Sophie D.; Widmark, Anders; Klepp, Olbjørn Harald; et al.

2013

Alpha Emitter Radium-223 and Survival in Metastatic Prostate Cancer

New England Journal of Medicine, Vol. 369, (3) : 213-223

Parker, C.; Nilsson, S.; Heinrich, D.; et al.

2013

Characterization of prostate cancer bone metastases according to expression levels of steroidogenic enzymes and androgen receptor splice variants

PLoS ONE, Public Library of Science 2013, Vol. 8, (11) : e77407-

Jernberg, Emma; Thysell, Elin; Bovinder Ylitalo, Erik; et al.

2013

Cohort Profile: The National Prostate Cancer Register of Sweden and Prostate Cancer data Base Sweden 2.0

International Journal of Epidemiology, Oxford: Oxford University Press 2013, Vol. 42, (4) : 956-967

Van Hemelrijck, Mieke; Wigertz, Annette; Sandin, Fredrik; et al.

2013

Early diagnosis and treatment is crucial for neurological recovery after surgery for metastatic spinal cord compression in prostate cancer

Acta Oncologica, London: Informa Healthcare 2013, Vol. 52, (4) : 809-815

Crnalic, Sead; Hildingsson, Christer; Bergh, Anders; et al.

2013

Hematologic safety of radium-223 dichloride (Ra-223) in the phase 3 ALSYMPCA trial in castration-resistant prostate cancer (CRPC) patients with bone metastases: baseline prognostic factor subgroup analysis

European Journal of Cancer, Elsevier 2013, Vol. 49, (Supplement 2) : S688-S688, Meeting Abstract: 2877

O'Sullivan, J.; Johannessen, D. C.; Widmark, Anders; et al.

2013

Hematologic Safety Profile of Radium-223 Dichloride (Ra-223) From the Phase 3 ALSYMPCA Trial in Castration-Resistant Prostate Cancer (CRPC) Patients With Bone Metastases

European Journal of Nuclear Medicine and Molecular Imaging, Springer-Verlag New York 2013, Vol. 40, (Supplement 2) : S189-S190

Widmark, Anders; Helle, S. I.; James, N.; et al.

2013

Inhibition of the insulin-like growth factor-1 receptor enhances effects of Simvastatin on prostate cancer cells in co-culture with bone

Cancer Microenvironment, Springer 2013, Vol. 6, (3) : 231-240

Nordstrand, Annika; Lundholm, Marie; Larsson, Andreas; et al.

2013

Late radiation effects to the rectum and anus after treatment for prostate cancer; validity of the LENT/SOMA score

Acta Oncologica, Taylor & Francis 2013, Vol. 52, (4) : 727-735

Lund, Jo-Å; Kaasa, Stein; Wibe, Arne; et al.

Visa publikationer i DiVA Fäll ihop
Forskningsprojekt

1 januari 2018 till 31 december 2028

Kostnadseffektivitet för ultra-hypofraktionerad strålbehandlingsteknik jämfört med konventionell strålbehandling för prostatacancer (PROCORT)

Forskningsämne: Cancer och onkologi, Vårdvetenskap

1 januari 1991

Prospektiv livskvalitetsstudie hos män som behandlats för prostatacancer (PCSS)

Forskningsämne: Cancer och onkologi, Vårdvetenskap

Fäll ihop

Anders Widmark

Senaste publikationer

Forskningsprojekt