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Umeå universitet
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Huvudmenyn dold.
Personalbild Anders Widmark

Anders Widmark

I min forskning vill jag förbättra behandling av prostatacancer. SPCG-7 studien visar att tillägget av strålbehandling vid lokal högrisktumör halverar risken att avlida i prostatacancer. 

Kontakt

E-post
anders.widmark@umu.se
Telefon
090-785 28 57, 070-584 43 30

Verksam vid

Anknytning
Professor vid Institutionen för strålningsvetenskaper Enhet: Onkologi
Plats
27C, Målpunkt QC11, NUS, NUS Umeå universitet, 901 87 Umeå
Hyaluronic acid spacer in prostate cancer radiotherapy: dosimetric effects, spacer stability and long-term toxicity and PRO in a phase II study
Radiation Oncology, BioMed Central (BMC) 2023, Vol. 18, (1)
Björeland, Ulrika; Notstam, Kristina; Fransson, Per; et al.
Effect of docetaxel added to bicalutamide in Hormone-Naïve non-metastatic prostate cancer with rising PSA, a randomized clinical trial (SPCG-14)
Acta Oncologica
Josefsson, Andreas; Jellvert, Åsa; Holmberg, Erik; et al.
Clinical and biological relevance of the transcriptomic-based prostate cancer metastasis subtypes MetA-C
Molecular Oncology, John Wiley & Sons 2022, (4)
Thysell, Elin; Köhn, Linda; Semenas, Julius; et al.
Epithelial and stromal characteristics of primary tumors predict the bone metastatic subtype of prostate cancer and patient survival after androgen-deprivation therapy
Cancers, MDPI 2022, Vol. 14, (21)
Wikström, Pernilla; Halin Bergström, Sofia; Josefsson, Andreas; et al.
A novel DNA methylation signature is associated with androgen receptor activity and patient prognosis in bone metastatic prostate cancer
Clinical Epigenetics, BioMed Central 2021, Vol. 13, (1)
Bovinder Ylitalo, Erik; Thysell, Elin; Landfors, Mattias; et al.
Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer (HYPO-RT-PC): patient-reported quality-of-life outcomes of a randomised, controlled, non-inferiority, phase 3 trial
The Lancet Oncology, Elsevier 2021, Vol. 22, (2) : 235-245
Fransson, Per; Nilsson, Per; Gunnlaugsson, Adalsteinn; et al.
Inhibition of STAT3 prevents bone metastatic progression of prostate cancer in vivo
The Prostate, John Wiley & Sons 2021, Vol. 81, (8) : 452-462
Hagberg Thulin, Malin; Määttä, Jorma; Linder, Anna; et al.
Registration of histopathology to magnetic resonance imaging of prostate cancer
Physics and Imaging in Radiation Oncology, Elsevier 2021, Vol. 18 : 19-25
Sandgren, Kristina; Nilsson, Erik; Keeratijarut Lindberg, Angsana; et al.
High monocyte count and expression of s100a9 and s100a12 in peripheral blood mononuclear cells are associated with poor outcome in patients with metastatic prostate cancer
Cancers, MDPI 2021, Vol. 13, (10)
Åberg, Anna-Maja; Halin Bergström, Sofia; Thysell, Elin; et al.
In Reply to Sari et al
International Journal of Radiation Oncology, Biology, Physics, Elsevier 2020, Vol. 107, (2) : 388-389
Aksnessaether, Bjorg Y.; Myklebus, Tor Age; Solberg, Arne; et al.
Second Cancers in Patients With Locally Advanced Prostate Cancer Randomized to Lifelong Endocrine Treatment With or Without Radical Radiation Therapy: Long-Term Follow-up of the Scandinavian Prostate Cancer Group-7 Trial
International Journal of Radiation Oncology, Biology, Physics, Elsevier 2020, Vol. 106, (4) : 706-714
Aksnessaether, Bjorg Y.; Myklebust, Tor Age; Solberg, Arne; et al.
Assessing Radiographic Response to 223Ra with an Automated Bone Scan Index in Metastatic Castration-Resistant Prostate Cancer Patients
Journal of Nuclear Medicine, Society of Nuclear Medicine and Molecular Imaging 2020, Vol. 61, (5) : 671-675
Anand, Aseem; Tragardh, Elin; Edenbrandt, Lars; et al.
Radical radiotherapy for prostate cancer: patterns of care in Sweden 1998-2016
Acta Oncologica, Taylor & Francis 2020, Vol. 59, (5) : 549-557
Beckmann, Kerri; Garmo, Hans; Nilsson, Per; et al.
Marked response to cabazitaxel in prostate cancer xenografts expressing androgen receptor variant 7 and reversion of acquired resistance by anti-androgens
The Prostate, John Wiley & Sons 2020, Vol. 80, (2) : 214-224
Bovinder Ylitalo, Erik; Thysell, Elin; Thellenberg-Karlsson, Camilla; et al.
Comparative Effectiveness of Different Radical Radiotherapy Treatment Regimens for Prostate Cancer: A Population-Based Cohort Study
JNCI CANCER SPECTRUM, Oxford University Press 2020, Vol. 4, (2)
Pettersson, Andreas; Alm, Daniel; Garmo, Hans; et al.
Erectile Dysfunction and Absorbed Dose to Penile Base Structures in a Randomized Trial Comparing Ultrahypofractionated and Conventionally Fractionated Radiation Therapy for Prostate Cancer
International Journal of Radiation Oncology, Biology, Physics, Elsevier 2020, Vol. 107, (1) : 143-151
Rasmusson, Elisabeth; Gunnlaugsson, Adalsteinn; Wieslander, Elinore; et al.
Tumor-educated platelets for early prostate cancer diagnosis, and therapy stratification in patients with metastasized castration resistant prostate cancer
Clinical Cancer Research, American Association for Cancer Research 2020, Vol. 26, (11) : 73-74
Tjon-Kon-Fat, Lee-Ann; Köhn, Linda; Best, Myron; et al.
Editorial Comment: Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial
International Brazilian Journal of Urology, Vol. 46, (6) : 1100-1101
Widmark, Anders; Gunnlaugsson, Adalsteinn; Beckman, Lars; et al.
Erectile Dysfunction and Absorbed Dose to Penile Base Structures in a Randomized Trial Comparing Ultrahypofractionated and Conventionally Fractionated Radiotherapy for Prostate Cancer
International Journal of Radiation Oncology, Biology, Physics, Elsevier 2019, Vol. 105, (1) : S133-S134
Rasmusson, E.; Gunnlaugsson, A.; Wieslander, E.; et al.
Radiation dosimetry of [Ga-68]PSMA-11 in low-risk prostate cancer patients
EJNMMI Physics, Springer 2019, Vol. 6
Sandgren, Kristina; Johansson, Lennart; Axelsson, Jan; et al.
Gene expression profiles define molecular subtypes of prostate cancer bone metastases with different outcomes and morphology traceable back to the primary tumor
Molecular Oncology, John Wiley & Sons 2019, Vol. 13, (8) : 1763-1777
Thysell, Elin; Vidman, Linda; Bovinder Ylitalo, Erik; et al.
Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial
The Lancet, Elsevier 2019, Vol. 394, (10196) : 385-395
Widmark, Anders; Gunnlaugsson, Adalsteinn; Beckman, Lars; et al.
Phase 3 Assessment of the Automated Bone Scan Index as a Prognostic Imaging Biomarker of Overall Survival in Men With Metastatic Castration-Resistant Prostate Cancer: A Secondary Analysis of a Randomized Clinical Trial
JAMA Oncology, Vol. 4, (7) : 944-951
Armstrong, Andrew J.; Anand, Aseem; Edenbrandt, Lars; et al.
Bone remodeling in relation to androgen receptor activity in prostate cancer bone metastases
Cancer Research, American Association for Cancer Research 2018, Vol. 78, (16) : 50-50
Bovinder Ylitalo, Erik; Nordstrand, Annika; Thysell, Elin; et al.
The proteome of prostate cancer bone metastases
Cancer Research, American Association for Cancer Research 2018, Vol. 78, (16) : 91-92
Iglesias-Gato, Diego; Thysell, Elin; Crnalic, Sead; et al.
The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications
Clinical Cancer Research, American Association for Cancer Research 2018, Vol. 24, (21) : 5433-5444
Iglesias-Gato, Diego; Thysell, Elin; Tyanova, Stefka; et al.
Osteoblast-derived factors promote metastatic potential in human prostate cancer cells, in part via non-canonical transforming growth factor β (TGFβ) signaling
The Prostate, Vol. 78, (6) : 446-456
Karlsson, Terese; Sundar, Reshma; Widmark, Anders; et al.
Bone Cell Activity in Clinical Prostate Cancer Bone Metastasis and Its Inverse Relation to Tumor Cell Androgen Receptor Activity
International Journal of Molecular Sciences, MDPI 2018, Vol. 19, (4)
Nordstrand, Annika; Bovinder Ylitalo, Erik; Thysell, Elin; et al.
Three-year Safety of Radium-223 Dichloride in Patients with Castration-resistant Prostate Cancer and Symptomatic Bone Metastases from Phase 3 Randomized Alpharadin in Symptomatic Prostate Cancer Trial
European Urology, Elsevier 2018, Vol. 73, (3) : 427-435
Parker, Christopher C.; Coleman, Robert E.; Sartor, Oliver; et al.
Prostate Cancer Death After Radiotherapy or Radical Prostatectomy: A Nationwide Population-based Observational Study
European Urology, Elsevier 2018, Vol. 73, (4) : 502-511
Robinson, David; Garmo, Hans; Lissbrant, Ingela Franck; et al.
Histology correlation of in vivo [68Ga]PSMA-PET/MRI data of the prostate
Radiotherapy and Oncology, Elsevier 2018, Vol. 127 : S541-S541
Sandgren, Kristina; Jonsson, Joakim; Nyholm, Tufve; et al.
Clinically relevant molecular subgroups of prostate cancer bone metastases
Cancer Research, American Association for Cancer Research 2018, Vol. 78, (16) : 123-123
Thysell, Elin; Bovinder Ylitalo, Erik; Jernberg, Emma; et al.
Platelets harbor prostate cancer biomarkers and the ability to predict therapeutic response to abiraterone in castration resistant patients
The Prostate, Wiley-Blackwell 2018, Vol. 78, (1) : 48-53
Tjon-Kon-Fat, Lee-Ann; Lundholm, Marie; Schröder, Mona; et al.
Ultrahypofractionation for prostate cancer: Outcome from the Scandinavian phase 3 HYPO-RT-PC trial
Radiotherapy and Oncology, Elsevier 2018, Vol. 127 : S314-S314
Widmark, Anders; Gunnlaugsson, A.; Beckman, Lars; et al.
Cabazitaxel followed by androgen deprivation therapy (ADT) significantly improves time to progression in patients with newly diagnosed metastatic hormone sensitive prostate cancer (mHSPC): A randomized, open label, phase III, multicenter trial
Annals of Oncology, Elsevier 2017, Vol. 28, (S5) : v281-v281
Andren, O.; Widmark, Anders; Falt, A.; et al.
Prostate Cancer Radiation Therapy and Risk of Thromboembolic Events
International Journal of Radiation Oncology, Biology, Physics, Elsevier 2017, Vol. 97, (5) : 1026-1031
Bosco, Cecilia; Garmo, Hans; Adolfsson, Jan; et al.
Subgroups of castration-resistant prostate cancer bone metastases defined through an inverse relationship between androgen receptor activity and immune response
European Urology, Vol. 71, (5) : 776-787
Bovinder Ylitalo, Erik; Thysell, Elin; Jernberg, Emma; et al.
High Levels of the AR-V7 Splice Variant and Co-Amplification of the Golgi Protein Coding YIPF6 in AR Amplified Prostate Cancer Bone Metastases
The Prostate, Wiley-Blackwell Publishing Inc. 2017, Vol. 77, (6) : 625-638
Djusberg, Erik; Jernberg, Emma; Thysell, Elin; et al.
Inhibition of the insulin-like growth factor-1 receptor potentiates acute effects of castration in a rat model for prostate cancer growth in bone
Clinical and Experimental Metastasis, Springer 2017, Vol. 34, (3-4) : 261-271
Nordstrand, Annika; Halin Bergström, Sofia; Thysell, Elin; et al.
Survival Among Men at High Risk of Disseminated Prostate Cancer Receiving Initial Locally Directed Radical Treatment or Initial Androgen Deprivation Therapy
European Urology, Elsevier 2017, Vol. 72, (3) : 345-351
Sooriakumaran, Prasanna; Nyberg, Tommy; Akre, Olof; et al.
Hematologic Safety of Radium-223 Dichloride: Baseline Prognostic Factors Associated With Myelosuppression in the ALSYMPCA Trial
Clinical Genitourinary Cancer, CIG MEDIA GROUP, LP 2017, Vol. 15, (1) : 42-52
Vogelzang, Nicholas J.; Coleman, Robert E.; Michalski, Jeff M.; et al.
Metastatic spinal cord compression as the first sign of malignancy: Outcome after surgery in 69 patients
Acta Orthopaedica, Taylor & Francis 2017, Vol. 88, (4) : 457-462
Wänman, Johan; Grabowski, Pawel; Nyström, Helena; et al.
ATLAS: A phase 3 trial evaluating the efficacy of apalutamide (ARN-509) in patients with high-risk localized or locally advanced prostate cancer receiving primary radiation therapy
Annals of Oncology, Vol. 27
Bossi, A.; Dearnaley, D.; McKenzie, M.; et al.
Population-based study of long-term functional outcomes after prostate cancer treatment
BJU International, John Wiley & Sons 2016, Vol. 117, (6B) : E36-E45
Carlsson, Sigrid; Drevin, Linda; Loeb, Stacy; et al.
Ten- and 15-yr Prostate Cancer-specific Mortality in Patients with Nonmetastatic Locally Advanced or Aggressive Intermediate Prostate Cancer, Randomized to Lifelong Endocrine Treatment Alone or Combined with Radiotherapy: Final Results of The Scandinavian Prostate Cancer Group-7
European Urology, Vol. 70, (4) : 684-691
Fossa, Sophie D.; Wiklund, Fredrik; Klepp, Olbjorn; et al.
Long-term adverse effects after curative radiotherapy and radical prostatectomy: population-based nationwide register study
Scandinavian journal of urology, Vol. 50, (5) : 338-345
Fridriksson, Jón O.; Folkvaljon, Yasin; Nilsson, Per; et al.
Extratumoral Heme Oxygenase-1 (HO-1) Expressing Macrophages Likely Promote Primary and Metastatic Prostate Tumor Growth
PLOS ONE, Vol. 11, (6)
Halin Bergström, Sofia; Nilsson, Maria; Adamo, Hanibal; et al.
The Proteome of Primary Prostate Cancer
European Urology, Vol. 69, (5) : 942-952
Iglesias-Gato, Diego; Wikström, Pernilla; Tyanova, Stefka; et al.
Tumor Cell-Derived Exosomes from the Prostate Cancer Cell Line TRAMP-C1 Impair Osteoclast Formation and Differentiation
PLOS ONE, Vol. 11, (11)
Karlsson, Terese; Lundholm, Marie; Widmark, Anders; et al.
Extreme Hypofractionation versus Conventionally Fractionated Radiotherapy for Intermediate Risk Prostate Cancer: Early Toxicity Results from the Scandinavian Randomized Phase III Trial "HYPO-RT-PC"
International Journal of Radiation Oncology, Biology, Physics, Elsevier 2016, Vol. 96, (5) : 938-939
Widmark, Anders; Gunnlaugsson, A.; Beckman, L.; et al.
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