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Umeå universitet
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Personalbild Anders Widmark

Anders Widmark

I min forskning vill jag föbättra behandling av prostatacancer. SPCG-7 studien visar att tillägget av strålbehandling vid lokal högrisktumör halverar risken att avlida i prostatacancer. 

Kontakt

E-post
anders.widmark@umu.se
Telefon
090-785 28 57, 070-584 43 30

Verksam vid

Anknytning
Professor vid Institutionen för strålningsvetenskaper Enhet: Onkologi
Plats
27C, Målpunkt QC11, NUS, NUS Umeå universitet, 901 87 Umeå
2019
Marked response to cabazitaxel in prostate cancer xenografts expressing androgen receptor variant 7 and reversion of acquired resistance by anti-androgens
The Prostate
Bovinder Ylitalo, Erik; Thysell, Elin; Thellenberg-Karlsson, Camilla; et al.
2019
Erectile Dysfunction and Absorbed Dose to Penile Base Structures in a Randomized Trial Comparing Ultrahypofractionated and Conventionally Fractionated Radiotherapy for Prostate Cancer
International Journal of Radiation Oncology, Biology, Physics, Elsevier 2019, Vol. 105, (1) : S133-S134
Rasmusson, E.; Gunnlaugsson, A.; Wieslander, E.; et al.
2019
Radiation dosimetry of [Ga-68]PSMA-11 in low-risk prostate cancer patients
EJNMMI Physics, Springer 2019, Vol. 6
Sandgren, Kristina; Johansson, Lennart; Axelsson, Jan; et al.
2019
Gene expression profiles define molecular subtypes of prostate cancer bone metastases with different outcomes and morphology traceable back to the primary tumor
Molecular Oncology, John Wiley & Sons 2019, Vol. 13, (8) : 1763-1777
Thysell, Elin; Vidman, Linda; Bovinder Ylitalo, Erik; et al.
2019
Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial
The Lancet, Elsevier 2019, Vol. 394, (10196) : 385-395
Widmark, Anders; Gunnlaugsson, Adalsteinn; Beckman, Lars; et al.
2018
Phase 3 Assessment of the Automated Bone Scan Index as a Prognostic Imaging Biomarker of Overall Survival in Men With Metastatic Castration-Resistant Prostate Cancer: A Secondary Analysis of a Randomized Clinical Trial
JAMA Oncology, Vol. 4, (7) : 944-951
Armstrong, Andrew J.; Anand, Aseem; Edenbrandt, Lars; et al.
2018
Bone remodeling in relation to androgen receptor activity in prostate cancer bone metastases
Cancer Research, American Association for Cancer Research 2018, Vol. 78, (16) : 50-50
Bovinder Ylitalo, Erik; Nordstrand, Annika; Thysell, Elin; et al.
2018
The proteome of prostate cancer bone metastases
Cancer Research, American Association for Cancer Research 2018, Vol. 78, (16) : 91-92
Iglesias-Gato, Diego; Thysell, Elin; Crnalic, Sead; et al.
2018
The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications
Clinical Cancer Research, American Association for Cancer Research 2018, Vol. 24, (21) : 5433-5444
Iglesias-Gato, Diego; Thysell, Elin; Tyanova, Stefka; et al.
2018
Osteoblast-derived factors promote metastatic potential in human prostate cancer cells, in part via non-canonical transforming growth factor β (TGFβ) signaling
The Prostate, Vol. 78, (6) : 446-456
Karlsson, Terese; Sundar, Reshma; Widmark, Anders; et al.
2018
Bone Cell Activity in Clinical Prostate Cancer Bone Metastasis and Its Inverse Relation to Tumor Cell Androgen Receptor Activity
International Journal of Molecular Sciences, MDPI 2018, Vol. 19, (4)
Nordstrand, Annika; Bovinder Ylitalo, Erik; Thysell, Elin; et al.
2018
Three-year Safety of Radium-223 Dichloride in Patients with Castration-resistant Prostate Cancer and Symptomatic Bone Metastases from Phase 3 Randomized Alpharadin in Symptomatic Prostate Cancer Trial
European Urology, Elsevier 2018, Vol. 73, (3) : 427-435
Parker, Christopher C.; Coleman, Robert E.; Sartor, Oliver; et al.
2018
Prostate Cancer Death After Radiotherapy or Radical Prostatectomy: A Nationwide Population-based Observational Study
European Urology, Elsevier 2018, Vol. 73, (4) : 502-511
Robinson, David; Garmo, Hans; Lissbrant, Ingela Franck; et al.
2018
Histology correlation of in vivo [68Ga]PSMA-PET/MRI data of the prostate
Radiotherapy and Oncology, Elsevier 2018, Vol. 127 : S541-S541
Sandgren, Kristina; Jonsson, Joakim; Nyholm, Tufve; et al.
2018
Clinically relevant molecular subgroups of prostate cancer bone metastases
Cancer Research, American Association for Cancer Research 2018, Vol. 78, (16) : 123-123
Thysell, Elin; Bovinder Ylitalo, Erik; Jernberg, Emma; et al.
2018
Platelets harbor prostate cancer biomarkers and the ability to predict therapeutic response to abiraterone in castration resistant patients
The Prostate, Wiley-Blackwell 2018, Vol. 78, (1) : 48-53
Tjon-Kon-Fat, Lee-Ann; Lundholm, Marie; Schröder, Mona; et al.
2018
Ultrahypofractionation for prostate cancer: Outcome from the Scandinavian phase 3 HYPO-RT-PC trial
Radiotherapy and Oncology, Elsevier 2018, Vol. 127 : S314-S314
Widmark, Anders; Gunnlaugsson, A.; Beckman, Lars; et al.
2017
Cabazitaxel followed by androgen deprivation therapy (ADT) significantly improves time to progression in patients with newly diagnosed metastatic hormone sensitive prostate cancer (mHSPC): A randomized, open label, phase III, multicenter trial
Annals of Oncology, OXFORD UNIV PRESS 2017, Vol. 28
Andren, O.; Widmark, Anders; Falt, A.; et al.
2017
Prostate Cancer Radiation Therapy and Risk of Thromboembolic Events
International Journal of Radiation Oncology, Biology, Physics, Elsevier 2017, Vol. 97, (5) : 1026-1031
Bosco, Cecilia; Garmo, Hans; Adolfsson, Jan; et al.
2017
Subgroups of castration-resistant prostate cancer bone metastases defined through an inverse relationship between androgen receptor activity and immune response
European Urology, Vol. 71, (5) : 776-787
Bovinder Ylitalo, Erik; Thysell, Elin; Jernberg, Emma; et al.
2017
High Levels of the AR-V7 Splice Variant and Co-Amplification of the Golgi Protein Coding YIPF6 in AR Amplified Prostate Cancer Bone Metastases
The Prostate, Wiley-Blackwell Publishing Inc. 2017, Vol. 77, (6) : 625-638
Djusberg, Erik; Jernberg, Emma; Thysell, Elin; et al.
2017
Inhibition of the insulin-like growth factor-1 receptor potentiates acute effects of castration in a rat model for prostate cancer growth in bone
Clinical and Experimental Metastasis, Springer 2017, Vol. 34, (3-4) : 261-271
Nordstrand, Annika; Halin Bergström, Sofia; Thysell, Elin; et al.
2017
Survival Among Men at High Risk of Disseminated Prostate Cancer Receiving Initial Locally Directed Radical Treatment or Initial Androgen Deprivation Therapy
European Urology, Elsevier 2017, Vol. 72, (3) : 345-351
Sooriakumaran, Prasanna; Nyberg, Tommy; Akre, Olof; et al.
2017
Hematologic Safety of Radium-223 Dichloride: Baseline Prognostic Factors Associated With Myelosuppression in the ALSYMPCA Trial
Clinical Genitourinary Cancer, CIG MEDIA GROUP, LP 2017, Vol. 15, (1) : 42-52
Vogelzang, Nicholas J.; Coleman, Robert E.; Michalski, Jeff M.; et al.
2017
Metastatic spinal cord compression as the first sign of malignancy: Outcome after surgery in 69 patients
Acta Orthopaedica, Taylor & Francis 2017, Vol. 88, (4) : 457-462
Wänman, Johan; Grabowski, Pawel; Nyström, Helena; et al.
2016
ATLAS: A phase 3 trial evaluating the efficacy of apalutamide (ARN-509) in patients with high-risk localized or locally advanced prostate cancer receiving primary radiation therapy
Annals of Oncology, Vol. 27
Bossi, A.; Dearnaley, D.; McKenzie, M.; et al.
2016
Population-based study of long-term functional outcomes after prostate cancer treatment
BJU International, John Wiley & Sons 2016, Vol. 117, (6B) : E36-E45
Carlsson, Sigrid; Drevin, Linda; Loeb, Stacy; et al.
2016
Ten- and 15-yr Prostate Cancer-specific Mortality in Patients with Nonmetastatic Locally Advanced or Aggressive Intermediate Prostate Cancer, Randomized to Lifelong Endocrine Treatment Alone or Combined with Radiotherapy: Final Results of The Scandinavian Prostate Cancer Group-7
European Urology, Vol. 70, (4) : 684-691
Fossa, Sophie D.; Wiklund, Fredrik; Klepp, Olbjorn; et al.
2016
Long-term adverse effects after curative radiotherapy and radical prostatectomy: population-based nationwide register study
Scandinavian journal of urology, Vol. 50, (5) : 338-345
Fridriksson, Jón O.; Folkvaljon, Yasin; Nilsson, Per; et al.
2016
Extratumoral Heme Oxygenase-1 (HO-1) Expressing Macrophages Likely Promote Primary and Metastatic Prostate Tumor Growth
PLoS ONE, Vol. 11, (6)
Halin Bergström, Sofia; Nilsson, Maria; Adamo, Hanibal; et al.
2016
The Proteome of Primary Prostate Cancer
European Urology, Vol. 69, (5) : 942-952
Iglesias-Gato, Diego; Wikström, Pernilla; Tyanova, Stefka; et al.
2016
Tumor Cell-Derived Exosomes from the Prostate Cancer Cell Line TRAMP-C1 Impair Osteoclast Formation and Differentiation
PLoS ONE, Vol. 11, (11)
Karlsson, Terese; Lundholm, Marie; Widmark, Anders; et al.
2016
Extreme Hypofractionation versus Conventionally Fractionated Radiotherapy for Intermediate Risk Prostate Cancer: Early Toxicity Results from the Scandinavian Randomized Phase III Trial "HYPO-RT-PC"
International Journal of Radiation Oncology, Biology, Physics, Elsevier 2016, Vol. 96, (5) : 938-939
Widmark, Anders; Gunnlaugsson, A.; Beckman, L.; et al.
2015
Patient-reported gastrointestinal and genitourinary toxicity after prostate cancer treatment: A comparison between radiotherapy including pelvic nodes and prostate-only radiotherapy
Journal of Clinical Oncology, Vol. 33, (7 S)
Fransson, Per; Olofsson, Sebastian; Widmark, Anders; et al.
2015
External-beam radiation therapy (EBRT) use and safety with Radium-223 dichloride (Ra) in patients (pts) with castration-resistant prostate cancer (CRPC) and symptomatic bone metastases (mets) from the ALSYMPCA trial
Oncology Research and Treatment, Vol. 38 : 82-82
Stroelin, P.; O'Sullivan, J.; Sartor, O.; et al.
2015
Prospective assessment of urinary, gastrointestinal and sexual symptoms before, during and after image-guided volumetric modulated arc therapy for prostate cancer
Scandinavian journal of urology, Taylor & Francis 2015, Vol. 49, (1) : 58-69
Sveistrup, Joen; Widmark, Anders; Fransson, Per; et al.
2015
Lag time to adverse events after radical prostatectomy and curative radiotherapy
Journal of Clinical Oncology, Vol. 33, (7 S)
Thellenberg-Karlsson, Camilla; Fridriksson, Jon; Folkvaljon, Yasin; et al.
2014
Svensk medicinsk forskning behöver inte mer styrning
Läkartidningen, Vol. 111, (22-23) : 980-981
Andersén, Peter; Bäckström, Torbjörn; Dahlquist, Gisela; et al.
2014
Ten-and 15-year prostate cancer-specific survival in patients with nonmetastatic high-risk prostate cancer randomized to lifelong hormone treatment alone or combined with radiotherapy (SPCG VII)
Journal of Clinical Oncology, Vol. 32, (4)
Fossa, Sophie D.; Widmark, Anders; Klepp, Olbjørn Harald; et al.
2014
Change in prostate volume during extreme hypo-fractionation analysed with MRI
Radiation Oncology, Vol. 9 : 22-
Gunnlaugsson, Adalsteinn; Kjellen, Elisabeth; Hagberg, Oskar; et al.
2014
Prostate Tumor-Derived Exosomes Down-Regulate NKG2D Expression on Natural Killer Cells and CD8(+) T Cells: Mechanism of Immune Evasion
PLoS ONE, Vol. 9, (9) : e108925-
Lundholm, Marie; Schröder, Mona; Nagaeva, Olga; et al.
2014
EXTERNAL-BEAM RADIATION THERAPY (EBRT) USE AND SAFETY WITH RADIUM-223 DICHLORIDE (RA) IN PATIENTS (PTS) WITH CASTRATION-RESISTANT PROSTATE CANCER (CRPC) AND SYMPTOMATIC BONE METASTASES (METS) FROM THE ALSYMPCATRIAL
Annals of Oncology, Vol. 25, (suppl 4) : 768P-
O'Sullivan, J. M.; Sartor, O.; Parker, C.; et al.
2014
Effect of radium-223 dichloride on symptomatic skeletal events in patients with castration-resistant prostate cancer and bone metastases: results from a phase 3, double-blind, randomised trial
The Lancet Oncology, Vol. 15, (7) : 738-746
Sartor, Oliver; Coleman, Robert; Nilsson, Sten; et al.
2013
Early diagnosis and treatment is crucial for neurological recovery after surgery for metastatic spinal cord compression in prostate cancer
Acta Oncologica, London: Informa Healthcare 2013, Vol. 52, (4) : 809-815
Crnalic, Sead; Hildingsson, Christer; Bergh, Anders; et al.
2013
Characterization of prostate cancer bone metastases according to expression levels of steroidogenic enzymes and androgen receptor splice variants
PLoS ONE, Public Library of Science 2013, Vol. 8, (11) : e77407-
Jernberg, Emma; Thysell, Elin; Bovinder Ylitalo, Erik; et al.
2013
Treatment with curative intent and survival in men with high-risk prostate cancer: A population-based study of 11 380 men with serum PSA level 20-100 ng/mL
BJU International, Vol. 111, (3) : 381-388
Ladjevardi, Sam; Berglund, Anders; Varenhorst, Eberhard; et al.
2013
Population-based study on use of chemotherapy in men with castration resistant prostate cancer
Acta Oncologica, Informa Healthcare 2013, Vol. 52, (8) : 1593-1601
Lissbrant, Ingela Franck; Garmo, Hans; Widmark, Anders; et al.
2013
Late radiation effects to the rectum and anus after treatment for prostate cancer; validity of the LENT/SOMA score
Acta Oncologica, Taylor & Francis 2013, Vol. 52, (4) : 727-735
Lund, Jo-Å; Kaasa, Stein; Wibe, Arne; et al.
2013
Inhibition of the insulin-like growth factor-1 receptor enhances effects of Simvastatin on prostate cancer cells in co-culture with bone
Cancer Microenvironment, Springer 2013, Vol. 6, (3) : 231-240
Nordstrand, Annika; Lundholm, Marie; Larsson, Andreas; et al.
2013
Hematologic safety of radium-223 dichloride (Ra-223) in the phase 3 ALSYMPCA trial in castration-resistant prostate cancer (CRPC) patients with bone metastases: baseline prognostic factor subgroup analysis
European Journal of Cancer, Elsevier 2013, Vol. 49, (Supplement 2) : S688-S688, Meeting Abstract: 2877
O'Sullivan, J.; Johannessen, D. C.; Widmark, Anders; et al.
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