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Erik Johansson
Kontakt
E-post
erik.tm.johansson@umu.se
Telefon
090-786 66 38
,
072-205 93 20
Verksam vid
Anknytning
Professor vid
Institutionen för medicinsk kemi och biofysik
Roll: Prefekt
Plats
KB. A5, Campus, Umeå
Umeå universitet, 901 87 Umeå
Publikationer
Publikationer
Forskning
Forskning
Omnämnanden
Omnämnanden
2021
Unchecked nick ligation can promote localized genome re-replication
Current Biology
, Elsevier 2021, Vol. 31, (11) : R710-R711
Johansson, Erik; Diffley, John F X
2021
The [4Fe4S] Cluster of Yeast DNA Polymerase ϵ Is Redox Active and Can Undergo DNA-Mediated Signaling
Journal of the American Chemical Society
, American Chemical Society (ACS) 2021, Vol. 143, (39) : 16147-16153
Pinto, Miguel N.; ter Beek, Josy; Ekanger, Levi A.; et al.
2021
Eukaryotic DNA replication with purified budding yeast proteins
The DNA replication-repair interface
, Elsevier 2021 : 1-33
Posse, Viktor; Johansson, Erik; Diffley, John F. X.
2020
A whole-genome sequenced control population in northern Sweden reveals subregional genetic differences
PLOS ONE
, Public Library Science 2020, Vol. 15, (9)
Svensson, Daniel; Rentoft, Matilda; Dahlin, Anna M.; et al.
2019
Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase epsilon
Nature Communications
, Nature Publishing Group 2019, Vol. 10
Parkash, Vimal; Kulkarni, Yashraj; ter Beek, Josy; et al.
2019
A geographically matched control population efficiently limits the number of candidate disease-causing variants in an unbiased whole-genome analysis
PLOS ONE
, Public Library of Science 2019, Vol. 14, (3)
Rentoft, Matilda; Svensson, Daniel; Sjödin, Andreas; et al.
2019
Structural evidence for an essential Fe–S cluster in the catalytic core domain of DNA polymerase ϵ
Nucleic Acids Research
, Oxford University Press 2019, Vol. 47, (11) : 5712-5722
ter Beek, Josy; Parkash, Vimal; Bylund, Göran; et al.
2018
A mechanism for preventing asymmetric histone segregation onto replicating DNA strands
Science
, American Association for the Advancement of Science 2018, Vol. 361, (6409) : 1386-+-
Yu, Chuanhe; Gan, Haiyun; Serra-Cardona, Albert; et al.
2016
Strand displacement synthesis by yeast DNA polymerase epsilon
Nucleic Acids Research
, Oxford University Press 2016, Vol. 44, (17) : 8229-8240
Ganai, Rais A.; Zhang, Xiao-Ping; Heyer, Wolf-Dietrich; et al.
2016
DNA Replication - A Matter of Fidelity
Molecular Cell
, Vol. 62, (5) : 745-755
Ganai, Rais Ahmad; Johansson, Erik
2016
Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 113, (17) : 4723-4728
Rentoft, Matilda; Lindell, Kristoffer; Tran, Phong; et al.
2015
Switching between polymerase and exonuclease sites in DNA polymerase ε
Nucleic Acids Research
, Oxford University Press 2015, Vol. 43, (2) : 932-942
Ganai, Rais Ahmad; Bylund, Göran; Johansson, Erik
2015
Yeast DNA Polymerase epsilon Catalytic Core and Holoenzyme Have Comparable Catalytic Rates
Journal of Biological Chemistry
, USA: 2015, Vol. 290, (6) : 3825-3835
Ganai, Rais Ahmad; Osterman, Pia; Johansson, Erik
2015
Mammalian POLQ, Chromosome Stability and DNA Double-Strand Break Repair
Environmental and Molecular Mutagenesis
, Vol. 56 : S48-S48
Yousefzadeh, M. J.; Wyatt, D. W.; Takata, K.; et al.
2014
Structural basis for processive DNA synthesis by yeast DNA polymerase ε
Nature Structural & Molecular Biology
, Nature Publishing Group 2014, Vol. 21, (1) : 49-56
Hogg, Matthew; Osterman, Pia; Bylund, Göran; et al.
2014
Mechanism of suppression of chromosomal instability by DNA polymerase POLQ
PLOS Genetics
, Public library science 2014, Vol. 10, (10) : e1004654-
Yousefzadeh, Matthew J; Wyatt, David W; Takata, Kei-Ichi; et al.
2013
DNA och cancerutveckling
Cancerforskning på nya vägar: en bok från Froskningens dag 2013, Medicinska fakulteten vid Umeå universitet
, Umeå: Umeå universitet 2013 : 15-22
Johansson, Erik
2013
Replicative DNA polymerases
Cold Spring Harbor Perspectives in Biology
, Vol. 5, (6) : a012799-
Johansson, Erik; Dixon, Nicholas
2012
DNA Polymerase ε
The eukaryotic replisome: a guide to protein structure and function
, Springer Science+Business Media B.V. 2012 : 237-57
Hogg, Matthew; Johansson, Erik
2012
Promiscuous DNA synthesis by human DNA polymerase θ
Nucleic Acids Research
, Vol. 40, (6) : 2611-2622
Hogg, Matthew; Sauer-Eriksson, A Elisabeth; Johansson, Erik
2012
The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability
Nucleic Acids Research
, Vol. 40, (22) : 11545-11553
Isoz, Isabelle; Persson, Ulf; Volkov, Kirill; et al.
2012
RNase H2-Initiated Ribonucleotide Excision Repair
Molecular Cell
, Vol. 47, (6) : 980-986
Sparks, Justin L; Chon, Hyongi; Cerritelli, Susana M; et al.
2012
Proofreading of ribonucleotides inserted into DNA by yeast DNA polymerase ɛ.
DNA Repair
, Vol. 11, (8) : 649-656
Williams, Jessica S; Clausen, Anders R; Nick McElhinny, Stephanie A; et al.
2011
A top-down view on DNA replication and recombination from 9,000 feet above sea level
Genome Biology
, BioMed Central 2011, Vol. 12, (4)
Johansson, Erik; Speck, Christian; Chabes, Andrei
2011
Replication of ribonucleotide-containing DNA templates by yeast replicative polymerases
DNA Repair
, Vol. 10, (8) : 897-902
Watt, Danielle L; Johansson, Erik; Burgers, Peter M; et al.
2010
Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε
PLoS genetics
, Public Library of Science 2010, Vol. 6, (11) : e1001209-
Aksenova, Anna; Volkov, Kirill; Maceluch, Jaroslaw; et al.
2010
The eukaryotic replicative DNA polymerases take shape.
TIBS -Trends in Biochemical Sciences. Regular ed.
, Elsevier 2010, Vol. 35, (6) : 339-347
Johansson, Erik; MacNeill, Stuart A
2010
Genome instability due to ribonucleotide incorporation into DNA
Nature Chemical Biology
, Vol. 6, (10) : 774-81
Nick McElhinny, Stephanie A; Kumar, Dinesh; Clark, Alan B; et al.
2010
Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases.
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 107, (11) : 4949-4954
Nick McElhinny, Stephanie A; Watts, Brian E; Kumar, Dinesh; et al.
2009
Translesion synthesis of abasic sites by yeast DNA polymerase epsilon
The Journal of biological chemistry
, Vol. 284, (46) : 31555-31563
Sabouri, Nasim; Johansson, Erik
2008
Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage
Nucleic Acids Research
, Vol. 36, (17) : 5660-5667
Sabouri, Nasim; Viberg, Jörgen; Kumar, Dinesh; et al.
2008
Uracil recognition by replicative DNA polymerases is limited to the archaea, not occurring with bacteria and eukarya.
Nucleic Acids Research
, Vol. 36, (3) : 705-711
Wardle, Josephine; Burgers, Peter M J; Cann, Isaac K O; et al.
2007
The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA.
Nucleic Acids Research
, Vol. 35, (19) : 6588-6597
Chilkova, Olga; Stenlund, Peter; Isoz, Isabelle; et al.
2007
Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon.
Nucleic Acids Research
, Vol. 35, (9) : 3076-3086
Pursell, Zachary F; Isoz, Isabelle; Lundström, Else-Britt; et al.
2007
Yeast DNA polymerase epsilon participates in leading-strand DNA replication.
Science
, Vol. 317, (5834) : 127-130
Pursell, Zachary F; Isoz, Isabelle; Lundström, Else-Britt; et al.
2006
Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy.
Nature Structural & Molecular Biology
, Vol. 13, (1) : 35-43
Asturias, Francisco J; Cheung, Iris K; Sabouri, Nasim; et al.
2005
Saccharomyces cerevisiae DNA polymerase delta: high fidelity for base substitutions but lower fidelity for single- and multi-base deletions.
Journal of biological chemistry
, Vol. 280, (33) : 29980-7
Fortune, John M; Pavlov, Youri I; Welch, Carrie M; et al.
2004
Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication.
Genes & Development
, Vol. 18, (22) : 2764-2773
Garg, Parie; Stith, Carrie M; Sabouri, Nasim; et al.
2004
The Pol32 subunit of DNA polymerase delta contains separable domains for processive replication and proliferating cell nuclear antigen (PCNA) binding.
Journal of biological chemistry
, Vol. 279, (3) : 1907-15
Johansson, Erik; Garg, Parie; Burgers, Peter M J
2004
Enzymatic switching for efficient and accurate translesion DNA replication.
Nucleic Acids Research
, Vol. 32, (15) : 4665-75
McCulloch, Scott D; Kokoska, Robert J; Chilkova, Olga; et al.
2003
The quaternary structure of DNA polymerase epsilon from Saccharomyces cerevisiae.
Journal of Biological Chemistry
, Vol. 278, (16) : 14082-14086
Chilkova, Olga; Jonsson, Bengt-Harald; Johansson, Erik
2003
Unique error signature of the four-subunit yeast DNA polymerase epsilon.
Journal of Biological Chemistry
, Vol. 278, (44) : 43770-43780
Shcherbakova, Polina V; Pavlov, Youri I; Chilkova, Olga; et al.
2001
Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites.
Genes & Development
, Vol. 15, (8) : 945-54
Haracska, L; Unk, I; Johnson, R E; et al.
2001
Structure of DNA polymerase delta from Saccharomyces cerevisiae.
Journal of Biological Chemistry
, Vol. 276, (47) : 43824-8
Johansson, Erik; Majka, J; Burgers, P M
2001
Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence.
Journal of Biological Chemistry
, Vol. 276, (19) : 16439-46
Kamath-Loeb, A S; Loeb, L A; Johansson, Erik; et al.
2000
Functional interaction between the Werner Syndrome protein and DNA polymerase delta.
Proceedings or the National Academy of Sciences U S A
, Vol. 97, (9) : 4603-8
Kamath-Loeb, A S; Johansson, Erik; Burgers, P M; et al.
1998
Two YY-1-binding proximal elements regulate the promoter strength of the TATA-less mouse ribonucleotide reductase R1 gene.
Journal of Biological Chemistry
, Vol. 273, (45) : 29816-21
Johansson, Erik; Hjortsberg, K; Thelander, Lars
1996
Induction of the mouse ribonucleotide reductase R1 and R2 genes in response to DNA damage by UV light.
Journal of Biological Chemistry
, Vol. 271, (39) : 23698-704
Filatov, D; Björklund, Stefan; Johansson, Erik; et al.
1995
The TATA-less promoter of mouse ribonucleotide reductase R1 gene contains a TFII-I binding initiator element essential for cell cycle-regulated transcription.
Journal of Biological Chemistry
, Vol. 270, (50) : 30162-7
Johansson, Erik; Skogman, E; Thelander, Lars
1994
Gene structure and regulation of the expression of the R1 and R2 subunits of mouse ribonucleotide reductase.
Advances in Experimental Medicine and Biology
, Vol. 370 : 721-4
Johansson, Erik; Björklund, Stefan; Thelander, Lars
Visa publikationer i DiVA
Forskargrupper
Forskningsledare
Erik Johansson lab
Forskningsprojekt
1 januari 2022 till 31 december 2024
Kopiering av arvsmassan hos celler
1 juli 2000 till 31 december 2021
Kopiering och reparation av cellens arvsmassa
Publicerad: 28 okt, 2021
VR-miljoner till medicinsk forskning i Umeå
Publicerad: 12 nov, 2020
Nya Cancerfondsmiljoner till forskning vid Umeå universitet
Publicerad: 01 apr, 2019
Norrländskt blod ger genombrott i jakt på sjukdomsgener
Publicerad: 22 jan, 2019
Orsak funnen till extrem mängd mutationer i tumörer
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