Umeå universitet
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Personalbild Johan Trygg

Johan Trygg

Forskningen fokuserar på att utveckla avancerad data analys och kemometri på storskaliga 'omics' dataset för att förstå, förebygga och behandla sjukdomar och därigenom förbättra global hälsa. 

Kontakt

E-post
johan.trygg@umu.se
Telefon
090-786 69 17, 0730-64 71 37

Verksam vid

Anknytning
Professor vid Kemiska institutionen
Plats
KB.B4, Linnaeus väg 10, (rum: C4.13.19) Umeå universitet, 901 87 Umeå
Towards better process management in wastewater treatment plants: Process analytics based on SHAP values for tree-based machine learning methods
Journal of Environmental Management, Elsevier 2022, Vol. 301
Wang, Dong; Thunéll, Sven; Lindberg, Ulrika; et al.
A machine learning framework to improve effluent quality control in wastewater treatment plants
Science of the Total Environment, Elsevier 2021, Vol. 784
Wang, Dong; Thunéll, Sven; Lindberg, Ulrika; et al.
A robust and precise convnet for small non-coding rna classification (rpc-snrc)
IEEE Access, Vol. 9 : 19379-19390
Asim, Muhammad Nabeel; Malik, Muhammad Imran; Zehe, Christoph; et al.
DeepCeNS: An end-to-end Pipeline for Cell and Nucleus Segmentation in Microscopic Images
Proceedings of the International Joint Conference on Neural Networks
Khalid, Nabeel; Munir, Mohsin; Edlund, Christoffer; et al.
L2S-MirLoc: A Lightweight Two Stage MiRNA Sub-Cellular Localization Prediction Framework
Proceedings of the International Joint Conference on Neural Networks
Asim, Muhammad Nabeel; Ibrahim, Muhammad Ali; Zehe, Christoph; et al.
LIVECell: a large-scale dataset for label-free live cell segmentation
Nature Methods, Nature Publishing Group 2021, Vol. 18, (9) : 1038-1045
Edlund, Christoffer; Jackson, Timothy R.; Khalid, Nabeel; et al.
Multiblock variable influence on orthogonal projections (MB-VIOP) for enhanced interpretation of total, global, local and unique variations in OnPLS models
BMC Bioinformatics, BioMed Central 2021, Vol. 22, (1)
Galindo-Prieto, Beatriz; Geladi, Paul; Trygg, Johan
Out-of-Distribution Example Detection in Deep Neural Networks using Distance to Modelled Embedding
Sjögren, Rickard; Trygg, Johan
Overexpression of vesicle-associated membrane protein PttVAP27-17 as a tool to improve biomass production and the overall saccharification yields in Populus trees
Biotechnology for Biofuels, BioMed Central 2021, Vol. 14, (1)
Gandla, Madhavi Latha; Mähler, Niklas; Escamez, Sacha; et al.
Statistical analysis in metabolic phenotyping
Nature Protocols, Nature Publishing Group 2021, Vol. 16, (9) : 4299-4326
Blaise, Benjamin J.; Correia, Gonçalo D. S.; Haggart, Gordon A.; et al.
A whole-genome sequenced control population in northern Sweden reveals subregional genetic differences
PLOS ONE, Public Library Science 2020, Vol. 15, (9)
Svensson, Daniel; Rentoft, Matilda; Dahlin, Anna M.; et al.
Application of multiblock analysis on a small metabolomic multi-tissue dataset
Metabolites, MDPI 2020, Vol. 10, (7)
Torell, Frida; Skotare, Tomas; Trygg, Johan
MirLocPredictor: A ConvNet-Based Multi-Label MicroRNA Subcellular Localization Predictor by Incorporating k-Mer Positional Information
Genes, MDPI 2020, Vol. 11, (12)
Asim, Muhammad Nabeel; Malik, Muhammad Imran; Zehe, Christoph; et al.
Multivariate patent analysis: using chemometrics to analyze collections of chemical and pharmaceutical patents
Journal of Chemometrics, John Wiley & Sons 2020, Vol. 34, (1)
Sjögren, Rickard; Stridh, Kjell; Skotare, Tomas; et al.
Overexpression of VviPGIP1 and NtCAD14 in Tobacco Screened Using Glycan Microarrays Reveals Cell Wall Reorganisation in the Absence of Fungal Infection
Vaccines, MDPI 2020, Vol. 8, (3)
Weiller, Florent; Gerber, Lorenz; Trygg, Johan; et al.
Subspace Based Model Identification for an Industrial Bioreactor: Handling Infrequent Sampling Using Missing Data Algorithms
Processes, MDPI 2020, Vol. 8, (12)
Patel, Nikesh; Corbett, Brandon; Trygg, Johan; et al.
Visualization of descriptive multiblock analysis
Journal of Chemometrics, John Wiley & Sons 2020, Vol. 34, (1)
Skotare, Tomas; Sjögren, Rickard; Surowiec, Izabella; et al.
A geographically matched control population efficiently limits the number of candidate disease-causing variants in an unbiased whole-genome analysis
PLOS ONE, Public Library of Science 2019, Vol. 14, (3)
Rentoft, Matilda; Svensson, Daniel; Sjödin, Andreas; et al.
Cytokine Profiles in Autoantibody Defined Subgroups of Systemic Lupus Erythematosus
Journal of Proteome Research, American Chemical Society (ACS) 2019, Vol. 18, (3) : 1208-1217
Torell, Frida; Eketjäll, Susanna; Idborg, Helena; et al.
doepipeline: a systematic approach to optimizing multi-level and multi-step data processing workflows
BMC Bioinformatics, BioMed Central 2019, Vol. 20, (1)
Svensson, Daniel; Sjögren, Rickard; Sundell, David; et al.
Joint and unique multiblock analysis for integration and calibration transfer of NIR instruments
Analytical Chemistry, Washington: American Chemical Society (ACS) 2019, Vol. 91, (5) : 3516-3524
Skotare, Tomas; Nilsson, David; Xiong, Shaojun; et al.
Joint and unique multiblock analysis of biological data: multiomics malaria study
Faraday discussions (Online), Cambridge: Royal Society of Chemistry 2019, Vol. 218 : 268-283
Surowiec, Izabella; Skotare, Tomas; Sjögren, Rickard; et al.
Metabolic profiling of zebrafish embryo development from blastula period to early larval stages
PLOS ONE, San Francisco: Public Library of Science 2019, Vol. 14, (5)
Dhillon, Sundeep S.; Torell, Frida; Donten, Magdalena; et al.
Ultrasound imaging of dorsal neck muscles with speckle tracking analyses: the relationship between muscle deformation and force
Scientific Reports, Nature Publishing Group 2019, Vol. 9
Peterson, Gunnel; O'Leary, Shaun; Nilsson, David; et al.
A multi-omics approach reveals function of Secretory Carrier-Associated Membrane Proteins in wood formation of​ ​​Populus​​ ​trees
BMC Genomics, Springer Publishing Company 2018, Vol. 19
Obudulu, Ogonna; Mähler, Niklas; Skotare, Tomas; et al.
Alterations in the Mechanical Response of Deep Dorsal Neck Muscles in Individuals Experiencing Whiplash-Associated Disorders Compared to Healthy Controls: An Ultrasound Study
American Journal of Physical Medicine & Rehabilitation, LIPPINCOTT WILLIAMS & WILKINS 2018, Vol. 97, (2) : 75-82
Rahnama, Leila; Peterson, Gunnel; Kazemnejad, Anoshirvan; et al.
Kynurenine pathway is altered in patients with SLE and associated with severe fatigue
Lupus Science and Medicine, BMJ Publishing Group Ltd 2018, Vol. 5, (1)
Åkesson, Karolina; Pettersson, Susanne; Stahl, Sara; et al.
Metabolic Profiling of Multiorgan Samples: Evaluation of MODY5/RCAD Mutant Mice
Journal of Proteome Research, American Chemical Society (ACS) 2018, Vol. 17, (7) : 2293-2306
Torell, Frida; Bennet, Kate; Cereghini, Silvia; et al.
Neck-specific exercise improves impaired interactions between ventral neck muscles in chronic whiplash: A randomized controlled ultrasound study
Scientific Reports, Nature Publishing Group 2018, Vol. 8
Peterson, Gunnel; Nilsson, David; Trygg, Johan; et al.
OnPLS-Based Multi-Block Data Integration: A Multivariate Approach to Interrogating Biological Interactions in Asthma
Analytical Chemistry, AMER CHEMICAL SOC 2018, Vol. 90, (22) : 13400-13408
Reinke, Stacey N.; Galindo-Prieto, Beatriz; Skotare, Tomas; et al.
Quantification of run order effect on chromatography: mass spectrometry profiling data
Journal of Chromatography A, Vol. 1568 : 229-234
Surowiec, Izabella; Johansson, Erik; Stenlund, Hans; et al.
A new approach for variable influence on projection (VIP) in O2PLS models
Chemometrics and Intelligent Laboratory Systems, Elsevier 2017, Vol. 160 : 110-124
Galindo-Prieto, Beatriz; Trygg, Johan; Geladi, Paul
Association between pathology and texture features of multi parametric MRI of the prostate
Physics in Medicine and Biology, Vol. 62, (19) : 7833-7854
Kuess, Peter; Andrzejewski, Piotr; Nilsson, David; et al.
Dysregulations in circulating sphingolipids associate with disease activity indices in female patients with systemic lupus erythematosus: a cross-sectional study
Lupus, SAGE PUBLICATIONS LTD 2017, Vol. 26, (10) : 1023-1033
Checa, A.; Idborg, H.; Zandian, A.; et al.
Generalized Subset Designs in Analytical Chemistry
Analytical Chemistry, American Chemical Society (ACS) 2017, Vol. 89, (12) : 6491-6497
Surowiec, Izabella; Vikström, Ludvig; Hector, Gustaf; et al.
Haralick texture features from apparent diffusion coefficient (ADC) MRI images depend on imaging and pre-processing parameters
Scientific Reports, Nature Publishing Group 2017, Vol. 7
Brynolfsson, Patrik; Nilsson, David; Torheim, Turid; et al.
Lipid response patterns in acute phase paediatric Plasmodium falciparum malaria
Metabolomics, Vol. 13, (4)
Orikiiriza, Judy; Surowiec, Izabella; Lindquist, Elisabeth; et al.
Multivariate strategy for the sample selection and integration of multi-batch data in metabolomics
Metabolomics, SPRINGER 2017, Vol. 13, (10)
Surowiec, Izabella; Johansson, Erik; Torell, Frida; et al.
Protein expression in tension wood formation monitored at high tissue resolution in Populus
Journal of Experimental Botany, Oxford University Press 2017, Vol. 68, (13) : 3405-3417
Bygdell, Joakim; Srivastava, Vaibhav; Obudulu, Ogonna; et al.
The effects of thawing on the plasma metabolome: evaluating differences between thawed plasma and multi-organ samples
Metabolomics, Springer 2017, Vol. 13, (6)
Torell, Frida; Bennett, Kate; Rännar, Stefan; et al.
The oxylipin and endocannabidome responses in acute phase Plasmodium falciparum malaria in children
Malaria Journal, BIOMED CENTRAL LTD 2017, Vol. 16
Surowiec, Izabella; Gouveia-Figueira, Sandra; Orikiiriza, Judy; et al.
Altered mechanical deformation of the trapezius and multifidus muscles registered with ultrasonography in women with chronic whiplash-associated disorders
Manual Therapy, Vol. 25 : e58-
Peolsson, A.; Peterson, G.; Trygg, Johan; et al.
Changes in dorsal neck muscle function in individuals with chronic whiplash-associated disorders: a real-time ultrasound case-control study
Ultrasound in Medicine and Biology, Vol. 42, (5) : 1090-1102
Peterson, Gunnel; Nilsson, David; Peterson, Simon; et al.
Chemometric Analysis of Bacterial Peptidoglycan Reveals Atypical Modifications That Empower the Cell Wall against Predatory Enzymes and Fly Innate Immunity
Journal of the American Chemical Society, American Chemical Society (ACS) 2016, Vol. 138, (29) : 9193-9204
Espaillat, Akbar; Forsmo, Oskar; El Biari, Khouzaima; et al.
Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance
Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, (17) : 4723-4728
Rentoft, Matilda; Lindell, Kristoffer; Tran, Phong; et al.
Mechanical properties of the trapezius during scapular elevation in people with chronic whiplash associated disorders: A case-control ultrasound speckle tracking analysis
Manual Therapy, Vol. 21 : 177-182
Landén Ludvigsson, Maria; Peterson, Gunnel; Jull, Gwendolen; et al.
Metabolic Profiling of Systemic Lupus Erythematosus and Comparison with Primary Sjögren’s Syndrome and Systemic Sclerosis
PLOS ONE, Vol. 11, (7)
Bengtsson, Anders A.; Trygg, Johan; Wuttge, Dirk M.; et al.
Metabolite and Lipid Profiling of Biobank Plasma Samples Collected Prior to Onset of Rheumatoid Arthritis
PLOS ONE, Vol. 11, (10)
Surowiec, Izabella; Ärlestig, Lisbeth; Rantapää-Dahlqvist, Solbritt; et al.
Metabolomics study of fatigue in patients with rheumatoid arthritis na < ve to biological treatment
Rheumatology International, Vol. 36, (5) : 703-711
Surowiec, Izabella; Gjesdal, Clara Gram; Jonsson, Grete; et al.
Multi-platform metabolomics assays for human lung lavage fluids in an air pollution exposure study
Analytical and Bioanalytical Chemistry, Vol. 408, (17) : 4751-4764
Surowiec, Izabella; Karimpour, Masoumeh; Gouveia-Figueira, Sandra; et al.
Visa publikationer i DiVA

Forskargrupper

Forskningsledare
Johan Trygg Chemometrics Lab