Fatima Pedrosa-Domellöf

Jag är professor i ögonsjukdomar och forskar på ögonmusklerna. Forskning är min passion och orsaken till att jag kom till Sverige från Portugal för 30 år sen.

Vetenskaplig meritering: Docent

0000-0002-0648-4996

Kontakt

fatima.pedrosa-domellof@umu.se

090-786 55 94, 090-785 13 52

Verksam som

Professor, överläkare vid Institutionen för klinisk vetenskap Enhet: Oftalmiatrik

4, 7 tr, Norrlands Universitetssjukhus, Ögonkliniken Umeå universitet, Klinisk vetenskap, 901 85 Umeå

Anknuten som professor till Institutionen för medicinsk och translationell biologi Enhet: Grupp Per Stål, Lärare A-flygeln

Umeå universitet, 901 87 Umeå

Min forskning handlar om ”Ögonmusklernas molekylära uppbyggnad: ledtrådar till behandling av muskelsjukdomar och skelning”. Mer om detta kan du läsa under rubriken Forskning.

Jag driver podden Ögonvrån som fokuserar på just synen, ögon och ögonsjukdomar och lite till, riktad till allmänheten.

fhl2b mediates extraocular muscle protection in zebrafish models of muscular dystrophies and its ectopic expression ameliorates affected body muscles

Nature Communications, Springer Nature 2024, Vol. 15, (1)

Dennhag, Nils; Kahsay, Abraha; Nissen, Itzel; et al.

Obscurin maintains myofiber identity in extraocular muscles

Investigative Ophthalmology and Visual Science, Association for Research in Vision and Ophthalmology 2024, Vol. 65, (2)

Kahsay, Abraha; Dennhag, Nils; Liu, Jing-Xia; et al.

Myofiber type shift in extraocular muscles in amyotrophic lateral sclerosis

Investigative Ophthalmology and Visual Science, Association for Research in Vision and Ophthalmology (ARVO) 2023, Vol. 64, (5)

Behzadi, Arvin; Tjust, Anton Erik; Liu, Jing-Xia; et al.

Genetic compensation between Pax3 and Pax7 in zebrafish appendicular muscle formation

Developmental Dynamics, John Wiley & Sons 2022, Vol. 251, (9) : 1423-1438

Nord, Hanna; Kahsay, Abraha; Dennhag, Nils; et al.

Histochemistry and Cell Biology, Springer 2022, Vol. 158, (2) : 169-180

Vicente, André; Sloniecka, Marta; Liu, Jing-Xia; et al.

Long-term safety and efficacy of patisiran for hereditary transthyretin-mediated amyloidosis with polyneuropathy: 12-month results of an open-label extension study

Lancet Neurology, Elsevier 2021, Vol. 20, (1) : 49-59

Adams, David; Polydefkis, Michael; Gonzalez-Duarte, Alejandra; et al.

Cytoskeletal Proteins in Myotendinous Junctions of Human Extraocular Muscles

Investigative Ophthalmology and Visual Science, ARVO journals 2021, Vol. 62, (2) : 1-10

Liu, Jing-Xia; Domellöf, Fatima Pedrosa

Absence of Desmin in Myofibers of the Zebrafish Extraocular Muscles

Translational Vision Science & Technology, Association for Research in Vision and Ophthalmology 2020, Vol. 9, (10)

Dennhag, Nils; Liu, Jing-Xia; Nord, Hanna; et al.

The cytoskeleton of myotendinous junctions in human extraocular muscles

Investigative Ophthalmology and Visual Science, The Association for Research in Vision and Ophthalmology (ARVO) 2020, Vol. 61, (7)

Domellöf, Fatima Pedrosa; Liu, Jing-Xiu

Understanding the extraocular muscles: Connective tissue, motor endplates and the cytoskeleton

The Biochemist, Portland Press 2020, Vol. 42, (5) : 52-57

Liu, Jing-Xia; Dennhag, Nils; Domellöf, Fatima Pedrosa

Complex Correlations Between Desmin Content, Myofiber Types, and Innervation Patterns in the Human Extraocular Muscles

Investigative Ophthalmology and Visual Science, The Association for Research in Vision and Ophthalmology, Inc. (ARVO) 2020, Vol. 61, (3)

Liu, Jing-Xia; Domellöf, Fatima Pedrosa

The Extraocular Muscles Are Selectively Spared in ALS

Amyotrophic Lateral Sclerosis: Recent Advances and Therapeutic Challenges

Pedrosa Domellöf, Fatima

Sulfated Glycosaminoglycans as Viral Decoy Receptors for Human Adenovirus Type 37

Viruses, MDPI 2019, Vol. 11, (3)

Chandra, Naresh; Liu, Yan; Liu, Jing-Xia; et al.

Gene expression profile of extraocular muscles following resection strabismus surgery

Experimental Eye Research, Elsevier 2019, Vol. 182 : 182-193

Rodríguez, Maria Angels; Sandgren Hochhard, Karin; Vicente, André; et al.

Notch1 Signaling Pathway in Aniridia- Related Keratopathy, Normal Fetal and Adult Human Corneas

Investigative Ophthalmology and Visual Science, The Association for Research in Vision and Ophthalmology, Inc. 2018, Vol. 59, (9)

Byström, Berit; Vicente, André; Domellöf, Fatima Pedrosa

Chromatic pupillometry in children

Frontiers in Neurology, Frontiers Media S.A. 2018, Vol. 9

Crippa, Sylvain, V; Domellöf, Fatima Pedrosa; Kawasaki, Aki

Sarcomere remodelling and gene expression profile changes following strabismus surgery

Investigative Ophthalmology and Visual Science, The Association for Research in Vision and Ophthalmology, Inc. 2018, Vol. 59, (9)

Domellöf, Fatima Pedrosa; Rodriguez Garcia, Maria Angels; Vicente, André; et al.

A novel type of multiterminal motor endplate in human extraocular muscles

Investigative Ophthalmology and Visual Science, Rockville: The Association for Research in Vision and Ophthalmology 2018, Vol. 59, (1) : 539-548

Liu, Jing-Xia; Pedrosa-Domellöf, Fatima

Composition, architecture, and functional implications of the connective tissue network of the extraocular muscles

Investigative Ophthalmology and Visual Science, Rockville: The Association for Research in Vision and Ophthalmology 2018, Vol. 59, (1) : 322-329

McLoon, Linda K.; Vicente, André; Fitzpatrick, Krysta R.; et al.

Ryanodine receptor type 3 (RYR3) as a novel gene associated with a myopathy with nemaline bodies

European Journal of Neurology, Vol. 25, (6) : 841-847

Nilipour, Y.; Nafissi, S.; Tjust, Anton E.; et al.

The Cytoskeleton in the Extraocular Muscles of Desmin Knockout Mice

Investigative Ophthalmology and Visual Science, Vol. 59, (12) : 4847-4855

Rodríguez, Maria Angels; Liu, Jing-Xia; Parkkonen, Kimmo; et al.

Vivinex© toric lenses refractive results after cataract surgery, preliminary study including 50 eyes

Acta Ophthalmologica, Wiley-Blackwell 2018, Vol. 96, (S261) : 135-135

Vicente, André; Byström, B.; Domellöf, Fatima Pedrosa

Altered Signaling Pathways in Aniridia-Related Keratopathy

Investigative Ophthalmology and Visual Science, The Association for Research in Vision and Ophthalmology 2018, Vol. 59, (13) : 5531-5541

Vicente, André; Byström, Berit; Domellöf, Fatima Pedrosa

PLOS ONE, Public Library of Science 2018, Vol. 13, (6)

Vicente, André; Byström, Berit; Lindström, Mona; et al.

Exophiala phaeomuriformis keratitis in a subarctic climate region: a case report

Acta Ophthalmologica, John Wiley & Sons 2018, Vol. 96 : 425-428

Vicente, André; Pedrosa Domellöf, Fátima; Byström, Berit

Human Adenovirus Type 37 Uses αVβ1 and α3β1 Integrins for Infection of Human Corneal Cells

Journal of Virology, Vol. 91, (5)

Storm, Rickard J; Persson, David B; Skalman, Lars Nygård; et al.

Impact of Amyotrophic Lateral Sclerosis on Slow Tonic Myofiber Composition in Human Extraocular Muscles

Investigative Ophthalmology and Visual Science, ASSOC RESEARCH VISION OPHTHALMOLOGY INC 2017, Vol. 58, (9) : 3708-3715

Tjust, Anton E.; Danielsson, Adam; Andersen, Peter M.; et al.

Unchanged neurotrophic factors and their receptors correlate with sparing in extraocular muscles in amyotrophic lateral sclerosis

Investigative Ophthalmology and Visual Science, Rockville: The association for research in vision and ophthalmology 2016, Vol. 57, (15) : 6831-6842

Harandi, Vahid M; Gaied, Aida RN; Brännström, Thomas; et al.

A sturdy connective tissue network surrounds all the extraocular muscle fibers

Investigative Ophthalmology and Visual Science, ASSOC RESEARCH VISION OPHTHALMOLOGY INC 2016, Vol. 57, (12)

Pedrosa-Domellöf, Fatima; McLoon, Linda K.; Lindström, Mona

Loss of myofibers containing MyHC Slow tonic in extraocular muscles of terminal ALS patients with bulbar onset

Investigative Ophthalmology and Visual Science, ASSOC RESEARCH VISION OPHTHALMOLOGY INC 2016, Vol. 57, (12)

Tjust, Anton E.; Danielsson, Adam; Andersen, Peter M.; et al.

Desmin in extraocular muscles

Investigative Ophthalmology and Visual Science, ASSOC RESEARCH VISION OPHTHALMOLOGY 2015, Vol. 56, (7)

Domellöf, Fatima Pedrosa; Parkkonen, Kimmo; Lindström, Mona; et al.

Pax7-Positive Cells/Satellite Cells in Human Extraocular Muscles

Investigative Ophthalmology and Visual Science, Vol. 56, (10) : 6132-6143

Lindström, Mona; Tjust, Anton E.; Domellöf, Fatima Pedrosa

Sympathetic innervation of human muscle spindles

Journal of Anatomy, Vol. 226, (6) : 542-548

Radovanovic, Dina; Peikert, Kevin; Lindström, Mona; et al.

Fibre typing of intrafusal fibres

Journal of Anatomy, John Wiley & Sons 2015, Vol. 227, (2) : 136-156

Thornell, Lars-Eric; Carlsson, Lena; Eriksson, Per-Olof; et al.

Intermediate Filaments in the Human Extraocular Muscles

Investigative Ophthalmology and Visual Science, Vol. 55, (8) : 5151-5159

Janbaz, Adrihan H.; Lindström, Mona; Liu, Jingxia; et al.

Distinct changes in synaptic protein composition at neuromuscular junctions of extraocular muscles versus limb muscles of ALS donors

PLOS ONE, Vol. 8, (2) : e57473-

Liu, Jing-Xia; Brännström, Thomas; Andersen, Peter M; et al.

Extraocular muscles: Response to neuromuscular diseases and specific pathologies

Craniofacial Muscles: A New Framework for Understanding the Effector Side of Craniofacial Muscle Control, New York: Springer-Verlag New York 2013 : 75-90

Pedrosa-Domellöf, Fatima

Extraocular muscles: response to neuromusculardiseases and specific pathologies

Craniofacial muscles: A new framework for understanding the effector side of craniofacial muscle control, New York: Springer-Verlag New York 2012 : 75-90

Pedrosa Domellöf, Fatima

Unaffected motor endplate occupancy in eye muscles of ALS G93A mouse model

Frontiers in bioscience (Scholar edition), Frontiers in Bioscience 2012, Vol. 4 : 1547-1555

Tjust, Anton E; Brännstrom, Thomas; Pedrosa Domellöf, Fatima

Protein differences between human trapezius and vastus lateralis muscles determined with a proteomic approach

BMC Musculoskeletal Disorders, BioMed Central 2011, Vol. 12, (181) : 11-

Hadrevi, Jenny; Hellström, Fredrik; Kieselbach, Thomas; et al.

Different impact of ALS on laminin isoforms in human extraocular muscles versus limb muscles

Investigative Ophthalmology and Visual Science, Association for Research in Vision and Ophthalmology 2011, Vol. 52, (7) : 4842-4852

Liu, Jing-Xia; Brännström, Thomas; Andersen, Peter M; et al.

A continuum of myofibers in adult rabbit extraocular muscle: force, shortening velocity, and patterns of myosin heavy chain colocalization

Journal of applied physiology, Bethesda, Md.: American Physiological Society 2011, Vol. 111, (4) : 1178-1189