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Umeå universitet
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Huvudmenyn dold.
Personalbild Ludvig Backman

Ludvig Backman

Docent, universitetslektor i fysioterapi och funktionell anatomi

Vetenskaplig meritering: Docent
Pedagogisk meritering: Excellent lärare

Kontakt

E-post
ludvig.backman@umu.se
Telefon
090-786 52 03, 070-233 87 09

Verksam som

Anknytning
Universitetslektor vid Institutionen för samhällsmedicin och rehabilitering Enhet: Fysioterapi
Plats
-, - Umeå universitet, 901 87 Umeå
Anknytning
Anknuten som universitetslektor till Institutionen för medicinsk och translationell biologi Enhet: Lärare A-flygeln, Lärare D1-flygeln, Grupp Patrik Danielson
Plats
hus H, Johan Bures väg 12, Biologihuset Umeå universitet, 901 87 Umeå

Ludvig Backman är docent i anatomi vid Umeå universitet

Publikationslista (Google Scholar-profil)

CURRICULUM VITAE LUDVIG BACKMAN

Född 1983

Akademiska meriter och anställningar
• 2017 | Docent i anatomi
• 2017 | Universitetslektorat i fysioterapi och funktionell anatomi
• 2013 | Medicine doktor, anatomi
• 2009 | Magisterexamen, Idrottsmedicin, Umeå universitet
• 2008 | Sjukgymnastexamen, Karolinska Institutet

Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling
Bioactive Materials, Elsevier 2025, Vol. 44 : 319-338
Chen, Jialin; Sheng, Renwang; Mo, Qingyun; et al.
Corneal strain influences keratocyte proliferation and migration through upregulation of ALDH3A1 expression
The FASEB Journal, John Wiley & Sons 2024, Vol. 38, (23)
Zhang, Qian; Zhou, Xin; Zhang, Wei; et al.
fhl2b mediates extraocular muscle protection in zebrafish models of muscular dystrophies and its ectopic expression ameliorates affected body muscles
Nature Communications, Springer Nature 2024, Vol. 15, (1)
Dennhag, Nils; Kahsay, Abraha; Nissen, Itzel; et al.
Mechanical loading modulates AMPK and mTOR signaling in muscle cells
Journal of Proteome Research, American Chemical Society (ACS) 2024, Vol. 23, (10) : 4286-4295
Zhou, Xin; Zhu, Shaochun; Li, Junhong; et al.
Hydroxycamptothecin and substratum stiffness synergistically regulate fibrosis of human corneal fibroblasts
ACS Biomaterials Science & Engineering, American Chemical Society (ACS) 2023, Vol. 9, (2) : 959-967
Chen, Jialin; Mo, Qingyun; Long, Qiuzi; et al.
Material stiffness in cooperation with macrophage paracrine signals determines the tenogenic differentiation of mesenchymal stem cells
Advanced Science, John Wiley & Sons 2023, Vol. 10, (17)
Sheng, Renwang; Liu, Jia; Zhang, Wei; et al.
Secretome from myoblasts statically loaded at low intensity promotes tenocyte proliferation via the IGF-1 receptor pathway
The FASEB Journal, John Wiley & Sons 2023, Vol. 37, (10)
Li, Junhong; Zhou, Xin; Chen, Jialin; et al.
Advances in Regulatory Strategies of Differentiating Stem Cells towards Keratocytes
Stem Cells International, Hindawi Publishing Corporation 2022, Vol. 2022
Zhang, Aini; Zhang, Wei; Backman, Ludvig J.; et al.
Effects of Zinc, Magnesium, and Iron Ions on Bone Tissue Engineering
ACS Biomaterials Science & Engineering, American Chemical Society (ACS) 2022, Vol. 8, (6) : 2321-2335
Chen, Zhixuan; Zhang, Wei; Wang, Mingyue; et al.
Keratocyte Differentiation Is Regulated by NF-κB and TGFβ Signaling Crosstalk
International Journal of Molecular Sciences, MDPI 2022, Vol. 23, (19)
Zhou, Xin; Li, Junhong; Backman, Ludvig J.; et al.
Microstructured collagen films for 3D corneal stroma modelling
Connective Tissue Research, Taylor & Francis Group 2022, Vol. 63, (5) : 443-452
Prittinen, Juha; Zhou, Xin; Bano, Fouzia; et al.
Regulation of osteogenic differentiation by the pro-inflammatory cytokines IL-1β and TNF-α: current conclusions and controversies
Human Cell, Springer 2022, Vol. 35 : 957-971
Mo, Qingyun; Zhang, Wei; Zhu, Aijing; et al.
Topographic Orientation of Scaffolds for Tissue Regeneration: Recent Advances in Biomaterial Design and Applications
Biomimetics, MDPI 2022, Vol. 7, (3)
Chi, Jiayu; Wang, Mingyue; Chen, Jialin; et al.
Activation of NF-κB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion
Scientific Reports, Nature Publishing Group 2021, Vol. 11, (1)
Zhou, Xin; Backman, Ludvig J.; Danielson, Patrik
Anti-apoptotic effect of adipose tissue-derived stromal vascular fraction in denervated rat muscle
Stem Cell Research & Therapy, BioMed Central (BMC) 2021, Vol. 12, (1)
El-Habta, Roine; Andersson, Gustav; Kingham, Paul J.; et al.
Secretome from in vitro mechanically loaded myoblasts induces tenocyte migration, transition to a fibroblastic phenotype and suppression of collagen production
International Journal of Molecular Sciences, MDPI 2021, Vol. 22, (23)
Zhou, Xin; Li, Junhong; Giannopoulos, Antonios; et al.
Regulation of Keratocyte Phenotype and Cell Behavior by Substrate Stiffness
ACS Biomaterials Science & Engineering, American Chemical Society (ACS) 2020, Vol. 6, (9) : 5162-5171
Chen, Jialin; Backman, Ludvig J.; Zhang, Wei; et al.
Sustained Release of TPCA-1 from Silk Fibroin Hydrogels Preserves Keratocyte Phenotype and Promotes Corneal Regeneration by Inhibiting Interleukin-1β Signaling
Advanced Healthcare Materials, Wiley-VCH Verlagsgesellschaft 2020, Vol. 9, (17)
Zhang, Wei; Chen, Jialin; Qu, Mingli; et al.
Tannic acid-mediated dual peptide-functionalized scaffolds to direct stem cell behavior and osteochondral regeneration
Chemical Engineering Journal, Elsevier 2020, Vol. 396
Zhang, Wei; Ling, Chen; Liu, Haoyang; et al.
The Application of Mechanical Stimulations in Tendon Tissue Engineering
Stem Cells International, Hindawi Publishing Corporation 2020, Vol. 2020
Sheng, Renwang; Jiang, Yujie; Backman, Ludvig J.; et al.
Adipose stem cells enhance myoblast proliferation via acetylcholine and extracellular signal-regulated kinase 1/2 signaling
Muscle and Nerve, WILEY 2018, Vol. 57, (2) : 305-311
El-Habta, Roine; Kingham, Paul J.; Backman, Ludvig J.
Mechanical stress potentiates the differentiation of periodontal ligament stem cells into keratocytes
British Journal of Ophthalmology, BMJ Publishing Group Ltd 2018, Vol. 102, (4) : 562-569
Chen, Jialin; Zhang, Wei; Backman, Ludvig J.; et al.
Tendinosis-like changes in denervated rat Achilles tendon
BMC Musculoskeletal Disorders, BMC 2018, Vol. 19
El-Habta, Roine; Chen, Jialin; Pingel, Jessica; et al.
The adipose tissue stromal vascular fraction secretome enhances the proliferation but inhibits the differentiation of myoblasts
Stem Cell Research & Therapy, BioMed Central 2018, Vol. 9
El-Habta, Roine; Sloniecka, Marta; Kingham, Paul J.; et al.
Ascorbic Acid Promotes the Stemness of Corneal Epithelial Stem/Progenitor Cells and Accelerates Epithelial Wound Healing in the Cornea
Stem Cells Translational Medicine, WILEY 2017, Vol. 6, (5) : 1356-1365
Chen, Jialin; Lan, Jie; Liu, Dongle; et al.
Fos Promotes Early Stage Teno-Lineage Differentiation of Tendon Stem/Progenitor Cells in Tendon
Stem Cells Translational Medicine, John Wiley & Sons 2017, Vol. 6, (11) : 2009-2019
Chen, Jialin; Zhang, Erchen; Zhang, Wei; et al.
Glutamate signaling through the NMDA receptor reduces the expression of scleraxis in plantaris tendon derived cells
BMC Musculoskeletal Disorders, Vol. 18
Spang, Christoph; Backman, Ludvig J.; Le Roux, Sandrine; et al.
Nerve distributions in insertional Achilles tendinopathy - a comparison of bone, bursae and tendon
Histology and Histopathology, Vol. 32, (3) : 263-270
Andersson, Gustav; Backman, Ludvig J.; Christensen, Jens; et al.
Substance P and patterned silk biomaterial stimulate periodontal ligament stem cells to form corneal stroma in a bioengineered three-dimensional model
Stem Cell Research & Therapy, BIOMED CENTRAL LTD 2017, Vol. 8
Chen, Jialin; Zhang, Wei; Kelk, Peyman; et al.
Surface Topography and Mechanical Strain Promote Keratocyte Phenotype and Extracellular Matrix Formation in a Biomimetic 3D Corneal Model
Advanced Healthcare Materials, Wiley-VCH Verlagsgesellschaft 2017, Vol. 6, (5)
Zhang, Wei; Chen, Jialin; Backman, Ludvig J.; et al.
The Effects of Substance P and Acetylcholine on Human Tenocyte Proliferation Converge Mechanistically via TGF-β1
PLOS ONE, Vol. 12, (3)
Fong, Gloria; Backman, Ludvig J.; Alfredson, Håkan; et al.
Antiapoptotic Effect of Acetylcholine in Fas-Induced Apoptosis in Human Keratocytes
Investigative Ophthalmology and Visual Science, Vol. 57, (14) : 5892-5902
Sloniecka, Marta; Backman, Ludvig J.; Danielson, Patrik
Characterization and comparison of post-natal rat Achilles tendon-derived stem cells at different development stages
Scientific Reports, Vol. 6
Chen, Jialin; Zhang, Wei; Liu, Zeyu; et al.
Ciliary Neurotrophic Factor Promotes the Migration of Corneal Epithelial Stem/progenitor Cells by Up-regulation of MMPs through the Phosphorylation of Akt
Scientific Reports, Vol. 6
Chen, Jialin; Chen, Peng; Backman, Ludvig J.; et al.
Fat pads adjacent to tendinopathy: more than a coincidence?
British Journal of Sports Medicine, Vol. 50, (24) : 1491-1492
Ward, Ella Rose; Andersson, Gustav; Backman, Ludvig J.; et al.
The tenocyte phenotype of human primary tendon cells in vitro is reduced by glucocorticoids
BMC Musculoskeletal Disorders, Vol. 17
Spang, Christoph; Chen, Jialin; Backman, Ludvig J.
Transforming Growth Factor Beta 1 Modulates the Functional Expression of the Neurokinin-1 Receptor in Human Keratocytes
Current Eye Research, Vol. 41, (8) : 1035-1043
Roux, Sandrine Le; Borbely, Gabor; Słoniecka, Marta; et al.
Acetylcholine enhances keratocyte proliferation through muscarinic receptor activation.
International Immunopharmacology, Vol. 29, (1) : 57-62
Słoniecka, Marta; Backman, Ludvig J; Danielson, Patrik
Dexamethasone decreases substance P expression in human tendon cells: an in vitro study
Rheumatology, Oxford University Press 2015, Vol. 54, (2) : 318-323
Mousavizadeh, Rouhollah; Backman, Ludvig; McCormack, Robert G; et al.
Mutations in Collagen, Type XVII, Alpha 1 (COL17A1) Cause Epithelial Recurrent Erosion Dystrophy (ERED)
Human Mutation, John Wiley & Sons 2015, Vol. 36, (4) : 463-473
Jonsson, Frida; Byström, Berit; Davidson, Alice E.; et al.
Tendinopathy: Update on Pathophysiology
Journal of Orthopaedic and Sports Physical Therapy, Vol. 45, (11) : 833-841
Scott, Alex; Backman, Ludvig J.; Speed, Cathy
Substance P reduces TNF-α-induced apoptosis in human tenocytes through NK-1 receptor stimulation
British Journal of Sports Medicine, BMJ Publishing Group Ltd 2014, Vol. 48, (19) : 1414-1420
Backman, Ludvig J.; Eriksson, Daniella E.; Danielson, Patrik
Akt-mediated anti-apoptotic effects of substance P in Anti-Fas-induced apoptosis of human tenocytes
Journal of Cellular and Molecular Medicine, Wiley-Blackwell 2013, Vol. 17, (6) : 723-733
Backman, Ludvig J; Danielson, Patrik
Alpha-2 adrenergic stimulation triggers Achilles tenocyte hypercellularity: comparison between two model systems
Scandinavian Journal of Medicine and Science in Sports, John Wiley & Sons 2013, Vol. 23, (6) : 687-696
Backman, Ludvig J; Andersson, Gustav; Fong, Gloria; et al.
Human tenocytes are stimulated to proliferate by acetylcholine through an EGFR signalling pathway
Cell and Tissue Research, Springer-Verlag New York 2013, Vol. 351, (3) : 465-475
Fong, Gloria; Backman, Ludvig; Andersson, Gustav; et al.
Substance P enhances collagen remodeling and MMP-3 expression by human tenocytes
Journal of Orthopaedic Research, HOBOKEN, NJ, USA: Wiley-Blackwell 2013, Vol. 31, (1) : 91-98
Fong, Gloria; Backman, Ludvig J.; Hart, David A.; et al.
Endogenous substance P production in the Achilles tendon increases with loading in an in vivo model of tendinopathy: peptidergic elevation preceding tendinosis-like tissue changes
Journal of Musculoskeletal and Neuronal Interactions - JMNI, International Society of Musculoskeletal and Neuronal Interactions 2011, Vol. 11, (2) : 133-140
Backman, Ludvig; Andersson, Gustav; Wennstig, Gabriel; et al.
Low range of ankle dorsiflexion predisposes for patellar tendinopathy in junior elite basketball players: a 1-year prospective study
American Journal of Sports Medicine, Vol. 39, (12) : 2626-2633
Backman, Ludvig J; Danielson, Patrik
Substance P accelerates hypercellularity and angiogenesis in tendon tissue and enhances paratendinitis in response to Achilles tendon overuse in a tendinopathy model
British Journal of Sports Medicine, Loughborough: British Assoc. of Sport and Medicine 2011, Vol. 45, (13) : 1017-1022
Andersson, Gustav; Backman, Ludvig; Scott, Alexander; et al.
Substance P is a mechanoresponsive, autocrine regulator of human tenocyte proliferation
PLOS ONE, San Francisco, USA: Public Library of Science 2011, Vol. 6, (11) : e27209-
Backman, Ludvig; Fong, Gloria; Andersson, Gustav; et al.
Visa publikationer i DiVA

Jag undervisar främst inom fysioterapiprogrammet och läkarprogrammet i anatomi både, topografisk och funktionell anatomi. Jag är kursansvarig för anatomi-kursen inom fysioterapiprogrammet och har modulansvar inom läkarprogrammet för topografisk anatomi i muskuloskeletala systemet, med fokus på nedre extremiteter.

Jag blev utsedd till koordinator för formerande av det nya forskarutbildningsprogrammet av Medicinska fakulteten. Jag har en central roll i programmet sedan dess implementering, både som lärare och som ordförande för forskarutbildningsprogrammets programråd och som biträdande studierektor för forskarutbildningen.

Pedagogisk meritering

-       Meriterad lärare 2019

-       Excellent lärare 2024