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English
Magnus Wolf-Watz
Kontakt
E-post
magnus.wolf-watz@umu.se
Telefon
090-786 76 90
Verksam vid
Anknytning
Professor vid
Kemiska institutionen
Roll: Biträdande prefekt
Plats
KB.A3, Linnaeus väg 10, (rum: A3.13.07)
Umeå universitet, 901 87 Umeå
Publikationer
Publikationer
Forskning
Forskning
Omnämnanden
Omnämnanden
2022
Insights into the evolution of enzymatic specificity and catalysis: from Asgard archaea to human adenylate kinases
Science Advances
, American Association for the Advancement of Science (AAAS) 2022, Vol. 8, (44)
Verma, Apoorv; Åberg-Zingmark, Emma; Sparrman, Tobias; et al.
2021
Dynamic Connection between Enzymatic Catalysis and Collective Protein Motions
Biochemistry
, American Chemical Society (ACS) 2021, Vol. 60, (28) : 2246-2258
Ojeda-May, Pedro; Ul Mushtaq, Ameeq; Rogne, Per; et al.
2021
Tracking the ATP-binding response in adenylate kinase in real time
Science Advances
, American Association for the Advancement of Science 2021, Vol. 7, (47)
Orädd, Fredrik; Ravishankar, Harsha; Goodman, Jack; et al.
2021
Milligram scale expression, refolding, and purification of Bombyx mori cocoonase using a recombinant E. coli system
Protein Expression and Purification
, Elsevier 2021, Vol. 186
Phoeurk, Chanrith; Ul Mushtaq, Ameeq; Rogne, Per; et al.
2020
Mapping the Adenylate Kinase Reaction by Time-Resolved X-ray Solution Scattering
Biophysical Journal
, Cell Press 2020, Vol. 118, (3) : 50A-50A
Ravishankar, Harsha; Goodman, Jack; Nors Pedersen, Martin; et al.
2020
Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3
Biochemistry
, American Chemical Society (ACS) 2020, Vol. 59, (38) : 3570-3581
Rogne, Per; Dulko-Smith, Beata; Goodman, Jack; et al.
2020
Principles of ATP and GTP Selectivity in NMP Kinases
Biophysical Journal
, Cell Press 2020, Vol. 118, (3) : 193A-193A
Rogne, Per; Sauer-Eriksson, Elisabeth; Sauer, Uwe H.; et al.
2019
Dynamic pH‐induced conformational changes of the PsbO protein in the fluctuating acidity of the thylakoid lumen
Physiologia Plantarum
, John Wiley & Sons 2019, Vol. 166, (1) : 288-299
Carius, Anke B.; Rogne, Per; Duchoslav, Miloš; et al.
2019
Nucleation of an Activating Conformational Change by a Cation−Π Interaction
Biochemistry
, American Chemical Society (ACS) 2019, Vol. 58, (32) : 3408-3412
Rogne, Per; Andersson, David; Grundström, Christin; et al.
2019
Positive and Negative Substrate Interference Supported by Coinciding Enzyme Residues
Biophysical Journal
, CELL PRESS 2019, Vol. 116, (3) : 485A-485A
Wolf-Watz, Magnus; Rogne, Per; Sauer-Eriksson, A. Elisabeth; et al.
2018
Formation of a Secretion-Competent Protein Complex by a Dynamic Wrap-around Binding Mechanism
Journal of Molecular Biology
, Elsevier 2018, Vol. 430, (18, Part B) : 3157-3169
Gupta, Arun A.; Reinartz, Ines; Karunanithy, Gogulan; et al.
2018
Molecular mechanism of ATP versus GTP selectivity of adenylate kinase
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 115, (12) : 3012-3017
Rogne, Per; Rosselin, Marie; Grundström, Christin; et al.
2017
Characterization of the Ruler Protein Interaction Interface on the Substrate Specificity SwitchProtein in the
Yersinia
Type III Secretion System
Journal of Biological Chemistry
, Vol. 292, (8) : 3299-3311
Ho, Oanh; Rogne, Per; Edgren, Tomas; et al.
2017
Structural basis for ligand binding to an enzyme by a conformational selection pathway
Proceedings of the National Academy of Sciences of the United States of America
, National Academy of Sciences 2017, Vol. 114, (24) : 6298-6303
Kovermann, Michael; Grundström, Christin; Sauer-Eriksson, A. Elisabeth; et al.
2016
Protein dynamics and function from solution state NMR spectroscopy
Quarterly reviews of biophysics (Print)
, Cambridge University Press 2016, Vol. 49
Kovermann, Michael; Rogne, Per; Wolf-Watz, Magnus
2016
Urea-Dependent Adenylate Kinase Activation following Redistribution of Structural States
Biophysical Journal
, Vol. 111, (7) : 1385-1395
Rogne, Per; Wolf-Watz, Magnus
2016
Linkage between Fitness of Yeast Cells and Adenylate Kinase Catalysis
PLOS ONE
, Vol. 11, (9)
Tükenmez, Hasan; Magnussen, Helge; Kovermann, Michael; et al.
2015
Structural basis for catalytically restrictive dynamics of a high-energy enzyme state
Nature Communications
, Macmillan Publishers Ltd. 2015, Vol. 6
Kovermann, Michael; Ådén, Jörgen; Grundström, Christin; et al.
2015
Direct Correlation Between Ligand-Induced alpha-Synuclein Oligomers and Amyloid-like Fibril Growth
Scientific Reports
, Springer 2015, Vol. 5
Perdersen, Martin Nors; Fodera, Vito; Horvath, Istvan; et al.
2015
Real-time 31P NMR investigation on the catalytic behavior of the enzyme Adenylate kinase in the matrix of a switchable ionic liquid
ChemSusChem
, John Wiley & Sons 2015, Vol. 8, (2) : 3764-3768
Rogne, Per; Sparrman, Tobias; Anugwom, Ikenna; et al.
2015
Dynamics of a Naturally Hidden State Restricts Adenylate Kinase Activity
Biophysical Journal
, Vol. 108, (2) : 30A-30A
Wolf-Watz, Magnus; Kovermann, Michael
2014
Correlated Inter-Domain Motions in Adenylate Kinase
PloS Computational Biology
, PLOS 2014, Vol. 10, (7) : e1003721-
Esteban-Martin, Santiago; Fenwick, Robert Bryn; Ådén, Jörgen; et al.
2014
Negatively charged lipid membranes promote a disorder-order transition in the Yersinia YscU protein
Biophysical Journal
, Cell Press 2014, Vol. 107, (8) : 1950-1961
Weise, Christoph F; Login, Frédéric H; Ho, Oanh; et al.
2013
Structural topology and activation of an initial adenylate kinase-substrate complex
Biochemistry
, Vol. 52, (6) : 1055-1061
Ådén, Jörgen; Weise, Christoph; Brännström, Kristoffer; et al.
2013
Genetic dissection of a motility-associated c-di-GMP signalling protein of
Pseudomonas putida
Environmental Microbiology Reports
, Hoboken: Wiley-Blackwell 2013, Vol. 5, (4) : 556-565
Österberg, Sofia; Åberg, Anna; Herrera Seitz, M. Karina; et al.
2012
Autoproteolysis and Intramolecular Dissociation of Yersinia YscU Precedes Secretion of Its C-Terminal Polypeptide YscU CC
PLOS ONE
, Vol. 7, (11)
Frost, Stefan; Ho, Oanh; Login, Frédéric H; et al.
2012
Mechanisms of Protein Oligomerization: Inhibitor of Functional Amyloids Templates α-Synuclein Fibrillation
Journal of the American Chemical Society
, American Chemical Society (ACS) 2012, Vol. 134, (7) : 3439-3444
Horvath, Istvan; Weise, Christoph F; Andersson, Emma K; et al.
2012
Modulation of a pre-existing conformational equilibrium tunes adenylate kinase activity
Journal of the American Chemical Society
, Washington: American Chemical Society (ACS) 2012, Vol. 134, (40) : 16562-16570
Ådén, Jörgen; Verma, Abhinav; Schug, Alexander; et al.
2011
Macromolecular crowding extended to a heptameric system: the co-chaperonin protein 10
Biochemistry
, American Chemical Society (ACS) 2011, Vol. 50, (14) : 3034-3044
Aguilar, Ximena; Weise, Christoph; Sparrman, Tobias; et al.
2011
The molecular and functional interaction between ICLN and HSPCo
38
modulates the regulation of cell volume
Journal of Biological Chemistry
, American Society for Biochemistry and Molecular Biology 2011, Vol. 286, (47) : 40659-40670
Dossena, Silvia; Gandini, Rosaria; Tamma, Grazia; et al.
2011
Cisplatin binds human copper chaperone Atox1 and promotes unfolding
in vitro
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 108, (17) : 6951-6956
Palm, Maria E; Weise, Christoph F; Lundin, Christina; et al.
2011
Novel "order-disorder-order" mechanism for adenylate kinase conformational change
Fifteenth Annual Conference of the Swedish Structural Biology Network, Tällberg 17-20 June, 2011
Wolf-Watz, Magnus
2011
Extraordinary μs-ms backbone dynamics in Arabidopsis thaliana peroxiredoxin Q
Biochimica et Biophysica Acta
, Elsevier 2011, Vol. 1814, (12) : 1880-1890
Ådén, Jörgen; Wallgren, Marcus; Storm, Patrik; et al.
2010
Dissecting the microscopic steps of the cyclophilin a enzymatic cycle on the biological substrate HIV-capsid by NMR
Journal of Molecular Biology
, Elsevier 2010, Vol. 403, (5) : 723-38
Bosco, Daryl A; Eisenmesser, Elan Zohar; Clarkson, Michael W; et al.
2010
Lability landscape and protease resistance of human insulin amyloid: a new insight into its molecular properties
Journal of Molecular Biology
, Elsevier 2010, Vol. 396, (1) : 60-74
Malisauskas, Mantas; Weise, Christoph; Yanamandra, Kiran; et al.
2010
Overlap between folding and functional energy landscapes for adenylate kinase conformational change
Nature communications
, Vol. 1, (8) : 111-
Olsson, Ulrika; Wolf-Watz, Magnus
2009
Transient Non-native Hydrogen Bonds Promote Activation of a Signaling Protein
Cell
, Vol. 139, (6) : 1109-18
Gardino, Alexandra K; Villali, Janice; Kivenson, Aleksandr; et al.
2009
Noncooperative folding of subdomains in Adenylate Kinase
Biochemistry
, ACS Publications 2009, Vol. 48, (9) : 1911-1927
Rundqvist, Louise; Ådén, Jörgen; Sparrman, Tobias; et al.
2008
Extreme temperature tolerance of a hyperthermophilic protein coupled to residual structure in the unfolded state
Journal of Molecular Biology
, Vol. 379, (4) : 845-858
Wallgren, Marcus; Ådén, Jörgen; Pylypenko, Olena; et al.
2007
Intrinsic motions along an enzymatic reaction trajectory.
Nature
, Vol. 450 : 838-44
Henzler-Wildman, Katherine A; Thai, Vu; Lei, Ming; et al.
2007
NMR identification of transient complexes critical to adenylate kinase catalysis
Journal of the American Chemical Society
, Vol. 129, (45) : 14003-12
Ådén, Jörgen; Wolf-Watz, Magnus
2005
Intrinsic dynamics of an enzyme underlies catalysis
Nature
, Vol. 438 : 117-21
Eisenmesser, Elan Z; Millet, Oscar; Labeikovsky, Wladimir; et al.
2004
AML1/Runx1 recruits calcineurin to regulate granulocyte macrophage colony-stimulating factor by Ets1 activation.
Journal of Biological Chemistry
, Vol. 279, (28) : 29398-29408
Liu, Hebin; Holm, Magnus; Xie, Xiao-Qi; et al.
2004
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair
Nature Structural & Molecular Biology
, Vol. 11 : 945-9
Wolf-Watz, Magnus; Thai, Vu; Henzler-Wildman, Katherine; et al.
2002
The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding.
J Mol Biol
, Vol. 322, (2) : 259-72
Bäckström, Stefan; Wolf-Watz, Magnus; Grundström, Christine; et al.
2001
Crystallization and preliminary studies of the DNA-binding runt domain of AML1.
Acta Crystallogr D Biol Crystallogr
, Vol. 57, (Pt 2) : 269-71
Bäckström, Stefan; Huang, Shenghua; Wolf-Watz, Magnus; et al.
2001
Chloride binding by the AML1/Runx1 transcription factor studied by NMR
FEBS Letters
, Vol. 488, (1-2) : 81-4
Wolf-Watz, Magnus; Bäckström, Stefan; Grundström, Thomas; et al.
The type III secretion regulatory proteins LcrV, LcrG and YopD, in Yersinia, form a tripartite complex
Rogne, Per; Ekestubbe, Sofie; Nordfelth, Roland; et al.
Arabidopsis thaliana peroxiredoxin Q is extraordinarily dynamic on the μs-ms timescale
Ådén, Jörgen; Wallgren, Marcus; Storm, Patrik; et al.
Visa publikationer i DiVA
Forskargrupper
Forskningsledare
Magnus Wolf-Watz lab
Forskningsprojekt
1 januari 2022 till 31 december 2025
Avkodning av fundamentala principer hos enzymatisk katalys
Publicerad: 07 nov, 2022
Spår av uråldriga organismer i mänskliga celler
Publicerad: 09 nov, 2021
VR-miljoner till forskning i naturvetenskap och teknik
Publicerad: 03 sep, 2021
Vetenskapligt samfund intervjuar professor Magnus Wolf-Watz
Publicerad: 20 jan, 2021
Nyinstallerade professorer vid Teknisk-naturvetenskaplig fakultet 2018
Publicerad: 30 sep, 2020
Drygt 58 miljoner till två forskningsprojekt vid Umeå universitet
Publicerad: 02 okt, 2019
Prestigefyllt amerikanskt forskningsanslag till Umeå universitet
Publicerad: 17 maj, 2019
Kempestiftelserna storsatsar på integrerad strukturbiologi
Publicerad: 13 dec, 2018
Proteindynamik – från mekanismer till funktion
Publicerad: 16 okt, 2018
Ny professor: Proteindynamik – från mekanismer till funktion
Publicerad: 20 aug, 2018
Växelverkan mellan proteiner hjälper Yersiniabakterien orsaka sjukdom
Publicerad: 02 nov, 2017
VR-medel till forskningsprojekt inom natur- och teknikvetenskap
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