Madeleine Ramstedt

Min forskning studerar interaktioner mellan bakterier och material

Kontakt

090-786 63 28

Verksam vid

Universitetslektor vid Kemiska institutionen Roll: Biträdande prefekt

KB.C6, Linnaeus väg 10, (rum: B6.27.07) Umeå universitet, 901 87 Umeå

Bakteriefilmer på olika ytor kan skapa problem inom ett flertal områden i vårt samhälle, men även vara oss till nytta. I min forskning fokuserar vi på att förstå hur bakterier koloniserar ytor och bildar så kallade biofilmer. Vi försöker därefter använda denna kunskap för att försöka förhindra bakterie-påväxt på olika engångsprodukter inom sjukvården. Vi hoppas på detta sätt kunna bidra till att på sikt minska så kallade främmande-kropps-infektioner. Vi bedriver även forskning där vi undersöker hur naturliga biofilmer i vattendrag påverkar läkemedel som spridits i miljön.

Forskningen i min grupp är mycket tvärvetenskaplig och vi samarbetar bland annat med kollegor i England och Brasilien. Mer information om detta samarbete finns (på engelska) via denna länk.

Denna länk leder till mer detaljerad beskrivning av några projekt (på engelska).

Antimicrobial peptide induced colloidal transformations in bacteria-mimetic vesicles: combining in silico tools and experimental methods

Journal of Colloid and Interface Science, Elsevier 2021, Vol. 596 : 352-363

Freire, Rafael V.M.; Pillco-Valencia, Yeny; da Hora, Gabriel C.A.; et al.

Do environmental pharmaceuticals affect the composition of bacterial communities in a freshwater stream?: A case study of the Knivsta river in the south of Sweden

Science of the Total Environment, Elsevier 2021, Vol. 763

Hagberg, Aleksandra; Gupta, Shashank; Rzhepishevska, Olena I; et al.

Comparative Study of NAP-XPS and Cryo-XPS for the Investigation of Surface Chemistry of the Bacterial Cell-Envelope

Frontiers in Chemistry, Frontiers Media S.A. 2021, Vol. 9

KjÃŠrvik, Marit; Ramstedt, Madeleine; Schwibbert, Karin; et al.

Activity of airway antimicrobial peptides against cystic fibrosis pathogens

Pathogens and Disease, Oxford University Press 2020, Vol. 78, (7)

Cabak, Andrea; Hovold, Gisela; Petersson, Ann-Cathrine; et al.

Cryogenic X-ray photoelectron spectroscopy determines surface composition of algal cells and gives insights into their spontaneous sedimentation

Algal Research, Elsevier 2020, Vol. 47

Gojkovic, Zivan; Shchukarev, Andrey; Ramstedt, Madeleine; et al.

Surface analysis of bacterial systems using cryo-X-ray photoelectron spectroscopy

Surface and Interface Analysis, John Wiley & Sons 2020, Vol. 52 : 792-801

Hagberg, Aleksandra; Rzhepishevska, Olena I; Semenets, Anastasiia; et al.

Cryo-XPS analysis reveals surface composition of microalgae

Applied Surface Science, Elsevier 2020, Vol. 526

Shchukarev, Andrey; Gojkovic, Zivan; Funk, Christiane; et al.

Bacterial surfaces in geochemistry: how can x-ray photoelectron spectroscopy help?

Analytical geomicrobiology: a handbook of instrumental techniques, Cambridge: Cambridge University Press 2019 : 262-287

Ramstedt, Madeleine; Leone, Laura; Shchukarev, Andrey

Evaluating Efficacy of Antimicrobial and Antifouling Materials for Urinary Tract Medical Devices: Challenges and Recommendations

Macromolecular Bioscience, John Wiley & Sons 2019, Vol. 19, (5)

Ramstedt, Madeleine; Ribeiro, Isabel A. C.; Bujdakova, Helena; et al.

Conformational Dynamics and Responsiveness of Weak and Strong Polyelectrolyte Brushes: Atomistic Simulations of Poly(dimethyl aminoethyl methacrylate) and Poly(2-(methacryloyloxy)ethyl trimethylammonium chloride)

Langmuir, Washington: American Chemical Society (ACS) 2019, Vol. 35, (14) : 5037-5049

Santos, Denys E. S.; Li, Danyang; Ramstedt, Madeleine; et al.

Biofilm formation – what we can learn from recent developments

Journal of Internal Medicine, Wiley-Blackwell 2018, Vol. 284, (4) : 332-345

Bjarnsholt, T.; Buhlin, K.; Dufrêne, Y. F.; et al.

Functionalization of zwitterionic polymer brushes, do they remain antifouling?

Surface and Interface Analysis, John Wiley & Sons 2018, Vol. 50, (11) : 1001-1006

Hakobyan, Shoghik; Rzhepishevska, Olena; Barbero, David R.; et al.

Protein nanosheet mechanics controls cell adhesion and expansion on low-viscosity liquids

Nano letters (Print), Washington: American Chemical Society (ACS) 2018, Vol. 18, (3) : 1946-1951

Kong, Dexu; Megone, William; Nguyen, Khai D. Q.; et al.

Characterization of clinically relevant model bacterial strains of Pseudomonas aeruginosa for anti-biofilm testing of materials

Acta Biomaterialia, Elsevier 2018, Vol. 76 : 99-107

Rzhepishevska, Olena I.; Limanska, Nataliia; Galkin, Mykola; et al.

In vitro methods for the evaluation of antimicrobial surface designs

Acta Biomaterialia, Vol. 70 : 12-24

Sjollema, Jelmer; Zaat, Sebastian A.J.; Fontaine, Veronique; et al.

Levofloxacin-loaded bone cement delivery system: highly effective against intracellular bacteria and Staphylococcus aureus biofilms

International Journal of Pharmaceutics, Elsevier 2017, Vol. 532, (1) : 241-248

Ferreira, Magda; Rzhepishevska, Olena; Grenho, Liliana; et al.

Polymer Brushes and Microorganisms

Polymer and Biopolymer Brushes: for Materials Science and Biotechnology, John Wiley & Sons 2017 : 515-552

Ramstedt, Madeleine

Cryo-XPS: probing intact interfaces in nature and life

Surface and Interface Analysis, John Wiley & Sons 2017, Vol. 49, (4) : 349-356

Shchukarev, Andrey; Ramstedt, Madeleine

Influence of Chelation Strength and Bacterial Uptake of Gallium Salicylidene Acylhydrazide on Biofilm Formation and Virulence by Pseudomonas aeruginosa

Journal of Inorganic Biochemistry, Elsevier 2016, Vol. 160 : 24-32

Hakobyan, Shoghik; Rzhepishevska, Olena; Björn, Erik; et al.

Rethinking chemistry in higher education towards technology-enhanced problem-based learning

Education Inquiry, Vol. 7, (2) : 115-135

Ramstedt, Madeleine; Hedlund, Tomas; Björn, Erik; et al.

Analysis of bacterial cell surface chemical composition using cryogenic X-ray photoelectron spectroscopy

Bacterial cell wall homeostasis: methods and protocols, New York, NY: Humana Press 2016 : 215-223

Ramstedt, Madeleine; Shchukarev, Andrey

Study of thiol-ene chemistry on polymer brushes and application to surface patterning and protein adsorption

Polymer Chemistry, Vol. 7, (4) : 979-990

Tan, Khooi Y.; Ramstedt, Madeleine; Colak, Burcu; et al.

Detecting Bacterial Surface Organelles on Single Cells using Optical Tweezers

Langmuir, American Chemical Society (ACS) 2016, Vol. 32, (18) : 4521-4529

Zakrisson, Johan; Singh, Bhupender; Svenmarker, Pontus; et al.

A multivariate approach to correlate bacterial surface properties to biofilm formation by lipopolysaccharide mutants of Pseudomonas aeruginosa

Colloids and Surfaces B: Biointerfaces, Elsevier 2015, Vol. 127, (0) : 182-191

Ruhal, Rohit; Antti, Henrik; Rzhepishevska, Olena; et al.

Natural green coating inhibits adhesion of clinically important bacteria

Scientific Reports, Nature Publishing Group 2015, Vol. 5 : 8287-

Trentin, Danielle S; Silva, Denise B; Frasson, Amanda P; et al.

Nano-engineering of SWNT networks for enhanced charge transport at ultralow nanotube loading

Advanced Materials, John Wiley & Sons 2014, Vol. 26, (19) : 3111-3117

Barbero, David; Boulanger, Nicolas; Ramstedt, Madeleine; et al.

Carbon nanotube networks: nano-engineering of SWNT networks for enhanced charge transport at ultralow nanotube loading

Advanced Materials, Wiley-VCH Verlagsgesellschaft 2014, Vol. 26, (19) : 3164-

Barbero, David; Boulanger, Nicolas; Ramstedt, Madeleine; et al.

Outer Membrane Remodeling: The Structural Dynamics and Electrostatics of Rough Lipopolysaccharide Chemotypes

Journal of Chemical Theory and Computation, Vol. 10, (6) : 2488-2497

Dias, Roberta P.; da Hora, Gabriel C. A.; Ramstedt, Madeleine; et al.

Proton and gallium(III) binding properties of a biologically active salicylidene acylhydrazide

Journal of Inorganic Biochemistry, Elsevier 2014, Vol. 138 : 9-15

Hakobyan, Shoghik; Boily, Jean-François; Ramstedt, Madeleine

Surface-initiated polymer brushes in the biomedical field: applications in membrane science, biosensing, cell culture, regenerative medicine and antibacterial coatings

Chemical Reviews, American Chemical Society (ACS) 2014, Vol. 114, (21) : 10976-11026

Krishnamoorthy, Mahentha; Hakobyan, Shoghik; Ramstedt, Madeleine; et al.

Cell wall composition of Bacillus subtilis changes as a function of pH and Zn²⁺ exposure: insights from cryo-XPS measurements

Langmuir, Vol. 30, (15) : 4367-4374

Ramstedt, Madeleine; Leone, Laura; Persson, Per; et al.

The gallium(III)-salicylidene acylhydrazide complex shows synergistic anti-biofilm effect and inhibits toxin production by Pseudomonas aeruginosa

Journal of Inorganic Biochemistry, Elsevier 2014, Vol. 138 : 1-8

Rzhepishevska, Olena; Hakobyan, Shoghik; Ekstrand-Hammarström, Barbro; et al.

Type III secretion system expression in oxygen-limited Pseudomonas aeruginosa cultures is stimulated by isocitrate lyase activity

Open Biology, Royal Society of Chemistry 2013, Vol. 3

Chung, Jade C. S.; Rzhepishevska, Olena; Ramstedt, Madeleine; et al.

Universal soldier: Pseudomonas aeruginosa - an opportunistic generalist

Frontiers in Biology, Springer 2013, Vol. 8, (4) : 387-394

Gross, Jeremy; Passmore, Ian J; Chung, Jade Cs; et al.

The surface charge of anti-bacterial coatings alters motility and biofilm architecture

Journal of Biomaterials Science. Polymer Edition, RSC Publishing 2013, Vol. 1, (6) : 589-602

Rzhepishevska, Olena; Hakobyan, Shoghik; Ruhal, Rohit; et al.

Decoupling geometrical and chemical cues directing epidermal stem cell fate on polymer brush-based cell micro-patterns

Integrative Biology, RSC Publishing 2013, Vol. 5, (6) : 899-910

Tan, Khooi Y; Lin, Hui; Ramstedt, Madeleine; et al.

Simple Dip-Coating Process for the Synthesis of Small Diameter Single-Walled Carbon Nanotubes-Effect of Catalyst Composition and Catalyst Particle Size on Chirality and Diameter

The Journal of Physical Chemistry C, Vol. 116, (22) : 12232-12239

Barzegar, Hamid R.; Nitze, Florian; Sharifi, Tiva; et al.

Enhanced biofilm formation by Escherichia coli LPS mutants defective in hep biosynthesis

PLoS ONE, Public library of science 2012, Vol. 7, (12) : e51241-

Nakao, Ryoma; Ramstedt, Madeleine; Wai, Sun Nyunt; et al.

NOD-like receptor activation by outer-membrane vesicles (OMVs) from non-O1 non-O139 Vibrio cholerae is modulated by the quorum sensing regulator HapR

Infection and Immunity, American Society for Microbiology 2011, Vol. 79, (4) : 1418-1427

Bielig, H; Rompikuntal, Pramod Kumar; Mitesh, Dongre; et al.

Monitoring surface chemistry changes in the bacterial cell wall: multivariate analysis of Cryo-X-ray photoelectron spectroscopy data

Journal of Biological Chemistry, Vol. 286, (14) : 12389-12396

Ramstedt, Madeleine; Nakao, Ryoma; Nyunt Wai, Sun; et al.

The antibacterial activity of Ga3+ is influenced by Llgand complexation as well as the bacterial carbon source

Antimicrobial Agents and Chemotherapy, Washington, D. C.: American Society for Microbiology 2011, Vol. 55, (12) : 5568-5580

Rzhepishevska, Olena; Ekstrand-Hammarström, Barbro; Popp, Maximilian; et al.

Protein-Resistant NTA-Functionalized Polymer Brushes for Selective and Stable Immobilization of Histidine-Tagged Proteins

Applied Materials & Interfaces, ACS 2010, Vol. 2, (1) : 193-202

Gautrot, Julien E; Huck, Wilhelm T S; Welch, Martin; et al.

Difficulties in determining valence for Ag⁰ nanoparticles using XPS—characterization of nanoparticles inside poly (3-sulphopropyl methacrylate) brushes

Surface and Interface Analysis, John Wiley & Sons, Ltd 2010, Vol. 42, (6-7) : 855-858

Ramstedt, Madeleine; Franklyn, Paul

Towards quorum-quenching catalytic antibodies

Chemical Communications, RSC Publishing 2009, (5) : 538-540

Kapadnis, Prashant B; Hall, Evan; Ramstedt, Madeleine; et al.

Bacterial and mammalian cell response to poly(3-sulfopropyl methacrylate) brushes loaded with silver halide salts

Biomaterials, Vol. 30, (8) : 1524-31

Ramstedt, Madeleine; Ekstrand-Hammarström, Barbro; Shchukarev, Andrey; et al.

Biofunctionalized protein resistant oligo(ethylene glycol)-derived polymer brushes as selective immobilization and sensing platforms

Biomacromolecules, American Chemical Society 2009, Vol. 10, (10) : 2885-94

Trmcic-Cvitas, Jelena; Hasan, Erol; Ramstedt, Madeleine; et al.

Surface modification of PDMS via self-organization of vinyl-terminated small molecules

Soft Matter, RSC Publishing 2009, Vol. 5, (11) : 2286-2293

van Poll, Maaike L; Khodabakhsh, Saghar; Brewer, Paul J; et al.

Synthesis and characterization of poly(3-sulfopropylmethacrylate) brushes for potential antibacterial applications

Langmuir, Vol. 23, (6) : 3314-21

Ramstedt, Madeleine; Cheng, Nan; Azzaroni, Omar; et al.

Wet chemical silver treatment of endotracheal tubes to produce antibacterial surfaces

Journal of biomedical materials research. Part B, Applied biomaterials, Vol. 83, (1) : 169-80

Ramstedt, Madeleine; Houriet, Raymond; Mossialos, Dimitris; et al.

A self-assembly approach to chemical micropatterning of poly(dimethylsiloxane)

Angewandte Chemie International Edition, Wiley 2007, Vol. 46, (35) : 6634-7

van Poll, Maaike L; Zhou, Feng; Ramstedt, Madeleine; et al.

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