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Umeå universitet
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Personalbild Mattias Forsell

Mattias Forsell

Vi studerar kroppens immunförsvar och hur det reagerar för att skapa skyddande immunitet efter infektion eller vaccination. 

Kontakt

E-post
mattias.forsell@umu.se
Telefon
090-785 32 08

Verksam vid

Anknytning
Universitetslektor vid Institutionen för klinisk mikrobiologi Enhet: Avdelningen för infektion och immunologi
Plats
M, Universitetssjukhuset by 6, 6C106 Umeå universitet, 901 85 Umeå

Mer om forskargruppen Forsell

High prevalence of persistent symptoms and reduced health-related quality of life 6 months after COVID-19
Frontiers In Public Health, Frontiers Media S.A. 2023, Vol. 11
Ahmad, Irma; Edin, Alicia; Granvik, Christoffer; et al.
Risk factors for impaired respiratory function post COVID-19: a prospective cohort study of nonhospitalized and hospitalized patients
Journal of Internal Medicine
Björsell, Tove; Sundh, Josefin; Lange, Anna; et al.
Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages
Nature Communications, Springer Nature 2023, Vol. 14, (1)
Chernyshev, Mark; Sakharkar, Mrunal; Connor, Ruth I.; et al.
Extracellular galectin 4 drives immune evasion and promotes T-cell apoptosis in pancreatic cancer
Cancer immunology research, American Association for Cancer Research 2023, Vol. 11, (1) : 72-92
Lidström, Tommy; Cumming, Joshua; Gaur, Rahul; et al.
Vaccine-induced correlate of protection against fatal COVID-19 in older and frail adults during waves of neutralization-resistant variants of concern: an observational study
The Lancet Regional Health: Europe
Vikström, Linnea; Fjällström, Peter; Gwon, Yong-Dae; et al.
At-home sampling to meet geographical challenges for serological assessment of SARS-CoV-2 exposure in a rural region of northern Sweden, March to May 2021: a retrospective cohort study
Eurosurveillance, European Centre for Disease Control and Prevention (ECDC) 2023, Vol. 28, (13)
Wigren, Julia; Vikström, Linnea; Rosendal, Ebba; et al.
Seroprevalence of SARS-CoV-2 in Sweden, April 26 to May 9, 2021
Scientific Reports, Nature Publishing Group 2022, Vol. 12, (1)
Beser, Jessica; Galanis, Ilias; Enkirch, Theresa; et al.
Immune responses after omicron infection in triple-vaccinated health-care workers with and without previous SARS-CoV-2 infection
Lancet. Infectious diseases (Print), Vol. 22, (7) : 943-945
Blom, Kim; Marking, Ulrika; Havervall, Sebastian; et al.
Probabilistic classification of anti-SARS-CoV-2 antibody responses improves seroprevalence estimates
Clinical & Translational Immunology (CTI), John Wiley & Sons 2022, Vol. 11, (3)
Castro Dopico, Xaquin; Muschiol, Sandra; Grinberg, Nastasiya F.; et al.
Hierarchical Clustering and Trajectory Analyses Reveal Viremia-Independent B-Cell Perturbations in HIV-2 Infection
Cells, MDPI 2022, Vol. 11, (19)
Johansson, Emil; Kerkman, Priscilla; Scharf, Lydia; et al.
Recall of preexisting cross-reactive B cell memory after Omicron BA.1 breakthrough infection
Science immunology, American Association for the Advancement of Science 2022, Vol. 7, (73)
Kaku, Chengzi I.; Bergeron, Alan J.; Ahlm, Clas; et al.
Broad anti–SARS-CoV-2 antibody immunity induced by heterologous ChAdOx1/mRNA-1273 vaccination
Science, American Association for the Advancement of Science 2022, Vol. 375, (6584) : 1041-1047
Kaku, Chengzi I.; Champney, Elizabeth R.; Normark, Johan; et al.
Convalescent plasma treatment in severely immunosuppressed patients hospitalized with COVID-19: an observational study of 28 cases
Infectious Diseases, Taylor & Francis Group 2022, Vol. 54, (4) : 283-291
Ljungquist, Oskar; Lundgren, Maria; Iliachenko, Elena; et al.
Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses
Science Translational Medicine, American Association for the Advancement of Science 2022, Vol. 14, (636)
Mittler, Eva; Wec, Anna Z.; Tynell, Janne; et al.
Serine protease inhibitors restrict host susceptibility to SARS-CoV-2 infections
mBio, American Society for Microbiology 2022, Vol. 13, (3)
Rosendal, Ebba; Mihai, Ionut Sebastian; Becker, Miriam; et al.
Serum concentration of extracellular cold-inducible RNA-binding protein is associated with respiratory failure in COVID-19
Frontiers in Immunology, Frontiers Media S.A. 2022, Vol. 13
Schagatay, Felix; Diamant, Klara; Lidén, Mats; et al.
Clinical and genomic characterisation of a fatal Puumala orthohantavirus case with low levels of neutralising antibodies
Infectious Diseases, Vol. 54, (10) : 766-772
Tuiskunen-Bäck, Anne; Rasmuson, Johan; Thunberg, Therese; et al.
Single-Dilution COVID-19 Antibody Test with Qualitative and Quantitative Readouts
mSphere, American Society for Microbiology 2021, Vol. 6, (2)
Bortz, Robert H.; Florez, Catalina; Laudermilch, Ethan; et al.
Airway antibodies emerge according to COVID-19 severity and wane rapidly but reappear after SARS-CoV-2 vaccination
JCI Insight, American Society for Clinical Investigation 2021, Vol. 6, (22)
Cagigi, Alberto; Yu, Meng; Österberg, Björn; et al.
The Tonsil Lymphocyte Landscape in Pediatric Tonsil Hyperplasia and Obstructive Sleep Apnea
Frontiers in Immunology, Frontiers Media S.A. 2021, Vol. 12
Carrasco, Anna; Sjölander, Isabella; Van Acker, Aline; et al.
Regulation of Decay Accelerating Factor Primes Human Germinal Center B Cells for Phagocytosis
Frontiers in Immunology, Frontiers Media S.A. 2021, Vol. 11
Dernstedt, Andy; Leidig, Jana; Holm, Anna; et al.
Convalescence plasma treatment of COVID-19: results from a prematurely terminated randomized controlled open-label study in Southern Sweden
BMC Research Notes, BioMed Central 2021, Vol. 14, (1)
Holm, Karin; Lundgren, Maria N.; Kjeldsen-Kragh, Jens; et al.
Generation of plasma cells and CD27-IgD- B cells during hantavirus infection is associated with distinct pathological findings
Clinical & Translational Immunology (CTI), John Wiley & Sons 2021, Vol. 10
Kerkman, Priscilla; Dernstedt, Andy; Tadala, Lalitha; et al.
Evaluation of 11 SARS-CoV-2 antibody tests by using samples from patients with defined IgG antibody titers
Scientific Reports, Nature Publishing Group 2021, Vol. 11, (1)
Lagerqvist, Nina; Maleki, Kimia T.; Verner-Carlsson, Jenny; et al.
MAIT cell activation is associated with disease severity markers in acute hantavirus infection
Cell Reports Medicine, Saunders Elsevier 2021, Vol. 2, (3)
Maleki, Kimia T.; Tauriainen, Johanna; García, Marina; et al.
Heterologous ChAdOx1 nCoV-19 and mRNA-1273 Vaccination
New England Journal of Medicine, Massachusetts Medical Society 2021, Vol. 385, (11) : 1049-1051
Normark, Johan; Vikström, Linnea; Yong-Dae, Gwon; et al.
Platelets mediate serological memory to neutralize viruses in vitro and in vivo
Blood Advances, American Society of Hematology 2020, Vol. 4, (16) : 3971-3976
Waltraud, Schrottmaier C.; Salzmann, Manuel; Badrnya, Sigrun; et al.
Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine
Proceedings of the National Academy of Sciences of the United States of America, Washington: National Academy of Science 2020, Vol. 117, (12) : 6675-6685
Wec, Anna Z.; Haslwanter, Denise; Abdiche, Yasmina N.; et al.
Growth-inhibition of cell lines derived from B cell lymphomas through antagonism of serotonin receptor signaling
Scientific Reports, Nature Publishing Group 2019, Vol. 9
Kolan, Shrikant S; Lidström, Tommy; Mediavilla, Tomás; et al.
Platelet-stored antibodies potently diminish viral infection in vitro and in vivo
Acta Physiologica, John Wiley & Sons 2019, Vol. 227, (S718) : 187-187
Schrottmaier, Waltraud C.; Salzmann, M.; Badrnya, S.; et al.
B cell profiling in malaria reveals expansion and remodeling of CD11c+ B cell subsets
JCI Insight, American Society for Clinical Investigation 2019, Vol. 4, (9)
Sundling, Christopher; Ronnberg, Caroline; Yman, Victor; et al.
Regulation of Subunit-Specific Germinal Center B Cell Responses to the HIV-1 Envelope Glycoproteins by Antibody-Mediated Feedback
Frontiers in Immunology, Frontiers Media S.A. 2017, Vol. 8
Forsell, Mattias N. E.; Kvastad, Linda; Sedimbi, Saikiran K.; et al.
The B cell response towards Puumala virus infection: can B cells be infected?
Scandinavian Journal of Immunology, John Wiley & Sons 2017, Vol. 86, (4) : 260-260
Kerkman, Priscilla; Tuiskunen-Bäck, Anne; Dernstedt, Andy; et al.
Modulation of lymphoma growth by a selective serotonin receptor antagonist
Scandinavian Journal of Immunology, John Wiley & Sons 2017, Vol. 86, (4) : 343-343
Kolan, Shrikant S.; Lidström, Tommy; Björk, Karl; et al.
The Wiskott-Aldrich syndrome protein regulates antigen processing and presentation by dendritic cells
Scandinavian Journal of Immunology, WILEY 2017, Vol. 86, (4) : 254-255
Oliveira, Mariana; Baptista, Marisa; Keszei, Marton; et al.
Activation of circulating platelets leads to innate-like delivery of potent antiviral antibodies
Scandinavian Journal of Immunology, John Wiley & Sons 2017, Vol. 86, (4) : 278-278
Waltraud, Schrottmaier; Anna-Liisa, Luik; Manuel, Salzmann; et al.
Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells
Nature Communications, Vol. 7
Baptista, Marisa A. P.; Keszei, Marton; Oliveira, Mariana; et al.
Variable immune response to SARS-CoV-2 mRNA vaccination in multiple sclerosis after rituximab treatment interruption
Gröning, Remigius; Dernstedt, Andy; Gardfjäll, Jenny; et al.
Visa publikationer i DiVA

Forskargrupper

Forskningsledare
Mattias Forsell Lab
Gruppmedlem
Katarina Olofsson

Vidare läsning

Vaccinets livräddande molekyler

Den kunskap forskarna fått genom Covid-19, kan vara till nytta vid framtida pandemier.

Vad säger antikroppstest om vårt immunförsvar?

Antikroppar är protein som bildas mot främmande ämnen som virus, och kan skräddarsys mot nya infektioner.

Forskar kring immunförsvarets reaktion på covid-19

Mattias Forsell och hans kollegor har startat en biobank - där följs de som diagnostiserats med covid-19.

Forskning på ett ögonblick med Mattias Forsell

Mattias Forsell forskar på hur kroppens B-celler fungerar och hur de kan användas. (Video, 1:09 min, 2016)