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Umeå universitet
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Huvudmenyn dold.
Personalbild Patrik Danielson
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Patrik Danielson

Prorektor  |  Rektors ställföreträdare

 

Professor i anatomi

Överläkare i ögonsjukdomar

 

Kontakt

E-post
patrik.danielson@umu.se
Plats
Besöksadress, se karta
Telefon
090-786 58 93, 070-336 80 30

Verksam som

Anknytning
Professor, överläkare vid Institutionen för medicinsk och translationell biologi Enhet: Grupp Ludvig Backman
Anknytning
Övrig/annan befattning vid Universitetsledningen Roll: Prorektor, Ställföreträdande rektor

Prorektors sekreterare:  Sara Rambe

_______________________________

 

Patrik Danielson är professor i anatomi vid Umeå universitet och överläkare i ögonsjukdomar vid Norrlands universitetssjukhus, samt prorektor för universitetet (dvs. rektors ställföreträdare).

Patrik finns på LinkedIn.

 

Prorektors ansvar och uppdrag


Prorektor ersätter rektor vid hennes bortavaro eller i övrigt på hennes uppdrag. Prorektor är utsedd av universitetsstyrelsen som rektors ställföreträdare på sex år (från 1 juli 2025), och har därutöver de ansvarsområden som rektor beslutar.

Vid Umeå universitet har rektor bestämt att prorektor arbetar brett med frågor på ledningsnivå inom både forskning och utbildning, och stöttar såväl rektor som vicerektorerna för dessa båda kärnområden. Några specifika områden som spänner över både forskning och utbildning och där prorektor av rektor fått ett särskilt ansvar är:

  • Samverkan, särskilt i Norra Sverige, inkl. innovationsfrågor och fundraising.
  • Campusutveckling
  • Etikfrågor, inkl. god forskningssed

Prorektor är även ansvarig i universitetsledningen för Kunskapsnoden.

Följande styrelser, nämnder och råd vid Umeå universitet leds av prorektor som ordförande:

Prorektor är därutöver ledamot i styrelsen för Umeå universitet Holding AB, Norrlands universitetssjukvårdsstyrelse samt ägarrådet för North Sweden European Office. 


_______________________________

 

Publikationslista:
Google Scholar-profil för Patrik Danielson

Forskningsprojekt:
Mekanismer för ärrbildning och vävnadsnedbrytning i kollagenrik vävnad


_______________________________



CV  |  Curriculum Vitae  |  PATRIK DANIELSON


Personligt

Född 1980, uppvuxen i Kramfors, Ångermanland.


Akademiska meriter och anställningar

  • 2016 | Professor/Överläkare, anatomi/specialist i ögonsjukdomar
  • 2014 | Professor i anatomi
  • 2012 | Docent i anatomi
  • 2009 | Universitetslektor i anatomi
  • 2007 | Medicine doktor (Med.dr), anatomi
  • 2007 | Leg. läkare
  • 2005 | Läkarexamen


Förtroendeuppdrag (urval)

  • Prorektor / Rektors ställföreträdare, Umeå universitet, 2025-
  • Ledamot, Regeringskansliets rådgivande grupp för life science, 2024-
  • Vice ordförande, Svenska Läkaresällskapet, 2024-
  • Dekan, Medicinska fakulteten, Umeå universitet, 2017-2025
  • Styrelseledamot, Svenska Sällskapet för Medicinsk Forskning (SSMF), 2019-2025
  • Ordförande, Nationella styrgruppen för ALF-avtalet, 2021
  • Ledamot (regeringsutsedd), Nationella styrgruppen för ALF-avtalet, 2015-18; 2019-2022 (adjungerad från 2023)
  • Ledamot (regeringsutsedd), Kommittén för kliniska studier, Vetenskapsrådet, 2018-2020
  • Ledamot, Svenska Läkaresällskapets nämnd, 2015-18
  • Prodekan, Medicinska fakulteten, Umeå universitet, 2014-17
  • Ledamot (lärarrepresentant), medicinska fakultetsnämnden, Umeå universitet, 2011-14
  • Ledamot (studeranderepresentant), universitetsstyrelsen, Umeå universitet, 2002-04
  • Ledamot (studeranderepresentant), medicinska fakultetsnämnden, Umeå universitet, 2001-04
  • Kårordförande, Umeå Medicinska Studentkår (tidigare Corpus), 2002-04


Nationella forskningsanslag (som huvudsökande; urval)

  • 2018-21 | Vetenskapsrådet: 4 800 tkr
  • 2014-17 | Vetenskapsrådet: 5 044 tkr
  • 2010-12 | Vetenskapsrådet: 2 100 tkr
  • 2017-23 | Ögonfonden: 1 160 tkr
  • 2011-15 | Svenska Läkaresällskapet: 1 200 tkr
  • 2011-17 | Cronqvists stiftelse: 900 tkr


Vetenskapliga publikationer

Länk till Google Scholar-profil


Priser och utmärkelser

  • European Society of Ophthalmology (SOE) Speaker of the Year på Svenska Ögonläkarföreningens Årsmöte 2017
  • Svenska Läkaresällskapets pris för bästa translationella forskning 2013
  • Umeå universitets karriärbidrag 2011
  • Kungl. Skytteanska Samfundets pris till yngre forskare vid Medicinska fakulteten 2010
  • Hedersmedlem på livstid i Umeå Medicinska Studentkår, 2007

 

 

 

 

Proteomic analysis of human corneal keratocytes reveals mechanical strain-dependent changes in cellular function
Investigative Ophthalmology and Visual Science, Association for Research in Vision and Ophthalmology (ARVO) 2026, Vol. 67, (4)
Zhang, Qian; Zhu, Shaochun; Mateus, André; et al.
Tissue architecture modulates compositional and structural properties of corneal myofibroblast-derived matrix
Translational Vision Science & Technology, Association for Research in Vision and Ophthalmology Inc. 2025, Vol. 14, (9)
Giannopoulos, Antonios; Backman, Ludvig J.; Danielson, Patrik
Nigericin Induces Paraptosis-Like Cell Death Instead of Pyroptosis in Corneal Keratocytes
The FASEB Journal, John Wiley & Sons 2025, Vol. 39, (12)
Mi, Xiangquan; Zhou, Xin; Zhu, Shaochun; et al.
Corneal strain influences keratocyte proliferation and migration through upregulation of ALDH3A1 expression
The FASEB Journal, John Wiley & Sons 2024, Vol. 38, (23)
Zhang, Qian; Zhou, Xin; Zhang, Wei; et al.
Microstructured collagen films for 3D corneal stroma modelling
Connective Tissue Research, Taylor & Francis Group 2022, Vol. 63, (5) : 443-452
Prittinen, Juha; Zhou, Xin; Bano, Fouzia; et al.
Keratocyte Differentiation Is Regulated by NF-κB and TGFβ Signaling Crosstalk
International Journal of Molecular Sciences, MDPI 2022, Vol. 23, (19)
Zhou, Xin; Li, Junhong; Backman, Ludvig J.; et al.
Activation of NF-κB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion
Scientific Reports, Nature Publishing Group 2021, Vol. 11, (1)
Zhou, Xin; Backman, Ludvig J.; Danielson, Patrik
Regulation of Keratocyte Phenotype and Cell Behavior by Substrate Stiffness
ACS Biomaterials Science & Engineering, American Chemical Society (ACS) 2020, Vol. 6, (9) : 5162-5171
Chen, Jialin; Backman, Ludvig J.; Zhang, Wei; et al.
Acetylcholine decreases formation of myofibroblasts and excessive extracellular matrix production in an in vitro human corneal fibrosis model
Journal of Cellular and Molecular Medicine, John Wiley & Sons 2020, Vol. 24, (8) : 4850-4862
Sloniecka, Marta; Danielson, Patrik
Sustained Release of TPCA-1 from Silk Fibroin Hydrogels Preserves Keratocyte Phenotype and Promotes Corneal Regeneration by Inhibiting Interleukin-1β Signaling
Advanced Healthcare Materials, Wiley-VCH Verlagsgesellschaft 2020, Vol. 9, (17)
Zhang, Wei; Chen, Jialin; Qu, Mingli; et al.
Substance P induces fibrotic changes through activation of the RhoA/ROCK pathway in an in vitro human corneal fibrosis model
Journal of Molecular Medicine, Springer Berlin/Heidelberg 2019, Vol. 97, (10) : 1477-1489
Sloniecka, Marta; Danielson, Patrik
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing
Investigative Ophthalmology and Visual Science, ASSOC RESEARCH VISION OPHTHALMOLOGY INC 2019, Vol. 60, (10) : 3669-3679
Wang, Xiaolei; Qu, Mingli; Li, Jing; et al.
Mechanical stress potentiates the differentiation of periodontal ligament stem cells into keratocytes
British Journal of Ophthalmology, BMJ Publishing Group Ltd 2018, Vol. 102, (4) : 562-569
Chen, Jialin; Zhang, Wei; Backman, Ludvig J.; et al.
Acetylcholine decreases formation of myofibroblasts and excessive extracellular matrix components production in an in vitro human corneal fibrosis model
Investigative Ophthalmology and Visual Science, The Association for Research in Vision and Ophthalmology, Inc. 2018, Vol. 59, (9)
Sloniecka, Marta; Danielson, Patrik
Substance P Promotes Fibrosis in Human Corneal Stroma
Wound Repair and Regeneration, Wound Healing Society 2018, Vol. 26, (1) : A22-A22
Sloniecka, Marta; Danielson, Patrik
Ascorbic Acid Promotes the Stemness of Corneal Epithelial Stem/Progenitor Cells and Accelerates Epithelial Wound Healing in the Cornea
Stem Cells Translational Medicine, WILEY 2017, Vol. 6, (5) : 1356-1365
Chen, Jialin; Lan, Jie; Liu, Dongle; et al.
Substance P and patterned silk biomaterial stimulate periodontal ligament stem cells to form corneal stroma in a bioengineered three-dimensional model
Stem Cell Research & Therapy, BIOMED CENTRAL LTD 2017, Vol. 8
Chen, Jialin; Zhang, Wei; Kelk, Peyman; et al.
Corneal Epithelium-Derived Neurotrophic Factors Promote Nerve Regeneration
Investigative Ophthalmology and Visual Science, ASSOC RESEARCH VISION OPHTHALMOLOGY INC 2017, Vol. 58, (11) : 4695-4702
Di, Guohu; Qi, Xia; Zhao, Xiaowen; et al.
The Effects of Substance P and Acetylcholine on Human Tenocyte Proliferation Converge Mechanistically via TGF-β1
PLOS ONE, Vol. 12, (3)
Fong, Gloria; Backman, Ludvig J.; Alfredson, Håkan; et al.
Acetylcholine regulates expression of lumican and collagen i in keratocytes in quiescent state and after transitioning to fibroblasts and myofibroblasts
Wound Repair and Regeneration, WILEY 2017, Vol. 25, (4) : A32-A32
Sloniecka, Marta U.; Danielson, Patrik
Glutamate signaling through the NMDA receptor reduces the expression of scleraxis in plantaris tendon derived cells
BMC Musculoskeletal Disorders, Vol. 18
Spang, Christoph; Backman, Ludvig J.; Le Roux, Sandrine; et al.
Surface Topography and Mechanical Strain Promote Keratocyte Phenotype and Extracellular Matrix Formation in a Biomimetic 3D Corneal Model
Advanced Healthcare Materials, Wiley-VCH Verlagsgesellschaft 2017, Vol. 6, (5)
Zhang, Wei; Chen, Jialin; Backman, Ludvig J.; et al.
Ciliary Neurotrophic Factor Promotes the Migration of Corneal Epithelial Stem/progenitor Cells by Up-regulation of MMPs through the Phosphorylation of Akt
Scientific Reports, Vol. 6
Chen, Jialin; Chen, Peng; Backman, Ludvig J.; et al.
Transforming Growth Factor Beta 1 Modulates the Functional Expression of the Neurokinin-1 Receptor in Human Keratocytes
Current Eye Research, Vol. 41, (8) : 1035-1043
Roux, Sandrine Le; Borbely, Gabor; Słoniecka, Marta; et al.
Antiapoptotic Effect of Acetylcholine in Fas-Induced Apoptosis in Human Keratocytes
Investigative Ophthalmology and Visual Science, Vol. 57, (14) : 5892-5902
Sloniecka, Marta; Backman, Ludvig J.; Danielson, Patrik
Substance P Enhances Keratocyte Migration and Neutrophil Recruitment through Interleukin-8
Molecular Pharmacology, Vol. 89, (2) : 215-225
Sloniecka, Marta; Le Roux, Sandrine; Zhou, Qingjun; et al.
The role of neurokinin A in corneal wound repair
Investigative Ophthalmology and Visual Science, Rockville, MD, USA: Assoc Research Vision Ophthalmology Inc 2015, Vol. 56, (7)
Borbely, Gabor; Löfgren, Filip; Sloniecka, Marta; et al.
Mutations in Collagen, Type XVII, Alpha 1 (COL17A1) Cause Epithelial Recurrent Erosion Dystrophy (ERED)
Human Mutation, John Wiley & Sons 2015, Vol. 36, (4) : 463-473
Jonsson, Frida; Byström, Berit; Davidson, Alice E.; et al.
Acetylcholine induces proliferation of keratocytes through activation of muscarinic receptors
Investigative Ophthalmology and Visual Science, Association for Research in Vision and Ophthalmology 2015, Vol. 56, (7)
Sloniecka, Marta; Backman, Ludvig J.; Danielson, Patrik
Expression Profiles of Neuropeptides, Neurotransmitters, and Their Receptors in Human Keratocytes In Vitro and In Situ
PLOS ONE, Public library science 2015, Vol. 10, (7)
Sloniecka, Marta; Le Roux, Sandrine; Boman, Peter; et al.
Substance P enhances keratocyte migration through activation of the phosphoinositide 3-kinase-Rac1/RhoA pathway
Wound Repair and Regeneration, Vol. 23, (2) : A40-A40
Sloniecka, Marta U.; Le Roux, S.; Danielson, Patrik
Acetylcholine enhances keratocyte proliferation through muscarinic receptor activation.
International Immunopharmacology, Vol. 29, (1) : 57-62
Słoniecka, Marta; Backman, Ludvig J; Danielson, Patrik
Substance P reduces TNF-α-induced apoptosis in human tenocytes through NK-1 receptor stimulation
British Journal of Sports Medicine, BMJ Publishing Group Ltd 2014, Vol. 48, (19) : 1414-1420
Backman, Ludvig J.; Eriksson, Daniella E.; Danielson, Patrik
Substance P promotes diabetic corneal epithelial wound healing through molecular mechanisms mediated via the neurokinin-1 receptor.
Diabetes, Vol. 63, (12) : 4262-4274
Yang, Lingling; Di, Guohu; Qi, Xia; et al.
Alpha-2 adrenergic stimulation triggers Achilles tenocyte hypercellularity: comparison between two model systems
Scandinavian Journal of Medicine and Science in Sports, John Wiley & Sons 2013, Vol. 23, (6) : 687-696
Backman, Ludvig J; Andersson, Gustav; Fong, Gloria; et al.
Akt-mediated anti-apoptotic effects of substance P in Anti-Fas-induced apoptosis of human tenocytes
Journal of Cellular and Molecular Medicine, Wiley-Blackwell 2013, Vol. 17, (6) : 723-733
Backman, Ludvig J; Danielson, Patrik
Teaming up to beat tendon pain: clinical and research excellence own the podium at ISTS (International Scientific Tendinopathy Symposium).
British Journal of Sports Medicine, London, England: British Medical Journal Publishing Group 2013, Vol. 47, (9) : 532-532
Danielson, Patrik; Scott, Alex
Human tenocytes are stimulated to proliferate by acetylcholine through an EGFR signalling pathway
Cell and Tissue Research, Springer-Verlag New York 2013, Vol. 351, (3) : 465-475
Fong, Gloria; Backman, Ludvig; Andersson, Gustav; et al.
Substance P enhances collagen remodeling and MMP-3 expression by human tenocytes
Journal of Orthopaedic Research, HOBOKEN, NJ, USA: Wiley-Blackwell 2013, Vol. 31, (1) : 91-98
Fong, Gloria; Backman, Ludvig J.; Hart, David A.; et al.
Sports and exercise-related tendinopathies: a review of selected topical issues by participants of the second International Scientific Tendinopathy Symposium (ISTS) Vancouver 2012
British Journal of Sports Medicine, London, England: BMJ Publishing Group 2013, Vol. 47, (9) : 536-+
Scott, Alex; Docking, Sean; Vicenzino, Bill; et al.
Trichostatin A Inhibits Transforming Growth Factor-beta-Induced Reactive Oxygen Species Accumulation and Myofibroblast Differentiation via Enhanced NF-E2-Related Factor 2-Antioxidant Response Element Signaling
Molecular Pharmacology, Vol. 83, (3) : 671-680
Yang, Lingling; Qu, Mingli; Wang, Yao; et al.
In situ hybridization studies favouring the occurrence of a local production of BDNF in the human Achilles tendon
Histology and Histopathology, Vol. 27, (9) : 1239-1246
Bagge, Johan; Danielson, Patrik; Forsgren, Sture
VGluT2 and NMDAR1 expression in cells in the inflammatory infiltrates in experimentally induced myositis: evidence of local glutamate signaling suggests autocrine/paracrine effects in an overuse injury model
Inflammation, Vol. 35, (1) : 39-48
Spang, Christoph; Scott, Alexander; Danielson, Patrik; et al.
Substance P accelerates hypercellularity and angiogenesis in tendon tissue and enhances paratendinitis in response to Achilles tendon overuse in a tendinopathy model
British Journal of Sports Medicine, Loughborough: British Assoc. of Sport and Medicine 2011, Vol. 45, (13) : 1017-1022
Andersson, Gustav; Backman, Ludvig; Scott, Alexander; et al.
Tenocyte hypercellularity and vascular proliferation in a rabbit model of tendinopathy: contralateral effects suggest the involvement of central neuronal mechanisms
British Journal of Sports Medicine, Vol. 45, (5) : 399-406
Andersson, Gustav; Forsgren, Sture; Scott, Alexander; et al.
Endogenous substance P production in the Achilles tendon increases with loading in an in vivo model of tendinopathy: peptidergic elevation preceding tendinosis-like tissue changes
Journal of Musculoskeletal and Neuronal Interactions - JMNI, International Society of Musculoskeletal and Neuronal Interactions 2011, Vol. 11, (2) : 133-140
Backman, Ludvig; Andersson, Gustav; Wennstig, Gabriel; et al.
Substance P is a mechanoresponsive, autocrine regulator of human tenocyte proliferation
PLOS ONE, San Francisco, USA: Public Library of Science 2011, Vol. 6, (11) : e27209-
Backman, Ludvig; Fong, Gloria; Andersson, Gustav; et al.
Low range of ankle dorsiflexion predisposes for patellar tendinopathy in junior elite basketball players: a 1-year prospective study
American Journal of Sports Medicine, Vol. 39, (12) : 2626-2633
Backman, Ludvig J; Danielson, Patrik
Physical activity level in Achilles tendinosis is associated with blood levels of pain-related factors: a pilot study
Scandinavian Journal of Medicine and Science in Sports, Vol. 21, (6) : E430-E438
Bagge, Johan; Gaida, JE; Danielson, Patrik; et al.
Mechanical force modulates scleraxis expression in bioartificial tendons
Journal of Musculoskeletal and Neuronal Interactions - JMNI, International Society of Musculoskeletal and Neuronal Interactions 2011, Vol. 11, (2) : 124-132
Scott, A; Danielson, Patrik; Abraham, T; et al.
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Framförallt deskriptiv och topografisk anatomi inom cirkulations- och respirationsorganens system för läkarstuderande termin 1, 2 och 3.